Patents by Inventor Colin Parrish

Colin Parrish has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Live-attenuated vaccine having mutations in viral polymerase for the treatment and prevention of canine influenza virus
    Patent number: 11065326
    Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive.
    Type: Grant
    Filed: October 1, 2019
    Date of Patent: July 20, 2021
    Assignees: University of Rochester, Cornell University
    Inventors: Luis Martinez-Sobrido, Aitor Nogales-Gonzalez, Colin Parrish
  • NS1 truncated virus for the development of canine influenza vaccines
    Patent number: 10973903
    Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based on the development of mutant CIV, having one or more mutations in segment 8, which induces a CIV-specific immune response in a subject.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: April 13, 2021
    Assignees: University of Rochester, Cornell University
    Inventors: Luis Martinez-Sobrido, Aitor Nogales-Gonzalez, Colin Parrish
  • NS1 Truncated Virus for the Development of Canine Influenza Vaccines
    Publication number: 20200206341
    Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based on the development of mutant CIV, having one or more mutations in segment 8, which induces a CIV-specific immune response in a subject.
    Type: Application
    Filed: August 19, 2016
    Publication date: July 2, 2020
    Inventors: Luis Martinez-Sobrido, Aitor NOGALES-GONZALEZ, Colin PARRISH
  • Single-cycle virus for the development of canine influenza vaccines
    Patent number: 10548966
    Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that one or more mutations in segment 4 of the viral genome produces a single cycle infectious CIV (sciCIV). The sciCIV does not allow for the production of infectious progeny, but is able to induce a CIV-specific immune response.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: February 4, 2020
    Assignees: UNIVERSITY OF ROCHESTER, CORNELL UNIVERSITY
    Inventors: Luis Martinez-Sobrido, Aitor Nogales-Gonzalez, Colin Parrish
  • Live-Attenuated Vaccine Having Mutations in Viral Polymerase for the Treatment and Prevention of Canine Influenza Virus
    Publication number: 20200023055
    Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive.
    Type: Application
    Filed: October 1, 2019
    Publication date: January 23, 2020
    Inventors: Luis Martinez-Sobrido, Aitor Nogales-Gonzalez, Colin Parrish
  • Live-attenuated vaccine having mutations in viral polymerase for the treatment and prevention of canine influenza virus
    Patent number: 10478489
    Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: November 19, 2019
    Assignees: University of Rochester, Cornell University
    Inventors: Luis Martinez-Sobrido, Aitor Nogales-Gonzalez, Colin Parrish
  • Single-Cycle Virus for the Development of Canine Influenza Vaccines
    Publication number: 20180256703
    Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that one or more mutations in segment 4 of the viral genome produces a single cycle infectious CIV (sciCIV). The sciCIV does not allow for the production of infectious progeny, but is able to induce a CIV-specific immune response.
    Type: Application
    Filed: August 19, 2016
    Publication date: September 13, 2018
    Inventors: Luis Martinez-Sobrido, Aitor Nogales-Gonzalez, Colin Parrish
  • Live-Attenuated Vaccine Having Mutations in Viral Polymerase for the Treatment and Prevention of Canine Influenza Virus
    Publication number: 20180243401
    Abstract: The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive.
    Type: Application
    Filed: August 19, 2016
    Publication date: August 30, 2018
    Inventors: Luis Martinez-Sobrido, Aitor Nogales-Gonzalez, Colin Parrish
  • Method and system for determining the torque induced in a rotating shaft
    Patent number: 7860665
    Abstract: A rotating shaft has a torsional oscillation frequency that is dependent on the stiffness of the shaft. The torsional oscillation frequency and the stiffness are dependent upon the operating conditions of the shaft. The torque of the rotating shaft is determined by measuring the torsional oscillation frequency of the rotating shaft; measuring the twist induced in the rotating shaft by the torque; and using the measured value of the torsional oscillation frequency and the measured value of the induced twist to determine the torque induced in the shaft.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: December 28, 2010
    Assignee: Rolls-Royce plc
    Inventors: Colin Parrish, James Roberts, Leighton Tipton