Abstract: A method uses body images and computer hardware and software to collect and analyze clinical data in patients experiencing pain. Pain location information is obtained by the drawing of an outline of the pain on a paper copy or electronic display of the body image. Composite images are generated representing aggregate data for specified patient groups. The coordinates of common anatomic landmarks on differently designed body images are mapped to each other, permitting integrated analysis of pain data, e.g., pain shape, centroid, meta centroid, from multiple body image designs and display of all pain data on a single body image design. Differences and similarities between groups of patients are displayed visually and numerically, and are used to assign the probability of a given patient belonging to a particular diagnostic group or category of disease severity.

Abstract: A method and system use a processor, video display and relational database to format, define, generate, maintain, distribute and analyze sets of related documents. The process stores document-specific data in a relational database. A computer-controlled video display guides the document author through the creation and maintenance of the documents, while enforcing the document structure and dependency rules. The creation of documents that relate to activities that require multiple actions at specified time points is driven by a time/action electronic matrix that serves as a central control mechanism for each document set; an example is a document set for use in clinical research studies of drugs.

Abstract: A method and a system for evaluation of a human disease by recording body sounds for extended periods of time by a microphone placed in contact with the body of the patient and using computer processing of body sound data to provide frequency domain and time domain sound amplitudes. A computer reads out a converted measurement of a sound taken by the microphone and places the data on the computer data bus for further processing. The method and system provide a diagnostic information on diseases, such as certain diseases of the gastro-intestinal tract and the heart, which generate abnormal body sounds and provide assessment of patient progress during treatment of such disease entities.

Abstract: A method for the treatment of congestive heart failure in humans using pirbuterol or pharmaceutically acceptable acid addition salts thereof.

Abstract: Methods for the treatment of congestive heart failure and ischemic heart disease using prazosin and trimazosin, and the pharmaceutically acceptable acid addition salts thereof.

Abstract: An ambulatory electrocardiographic tape recording (DCG) taken over an extended period of time, such as 24 hours, is analyzed with substantial accuracy by randomly selecting a sample of time periods of a specific duration (such as a 2% sample) and printing out a hard copy record of the electrocardiogram at these times for visual analysis. The simplicity of this method and the system performing it combined with high accuracy in quantifying cardiac arrhythmias makes it perferable for most clinical purposes to conventional methods of analyzing DCG's.