Abstract: A method for operating a train comprising two or more locomotives, the method comprising the steps of: a) Setting one or more locomotive control levels and choosing a selected route of travel; b) Calculating a target train speed profile and a target in-train force profile over at least a portion of the selected route; c) Measuring one or more operating parameters related to the operation of the train; d) Calculating a future train speed profile and a future in-train force profile for a future period based on at least one of the one or more operating parameters, at least one of the one or more locomotive control levels and one or more pieces of information relating to the selected route; e) Calculating adjusted locomotive speed control levels relating to the one or more operating parameters based on a difference between the target train speed profile and the future train speed profile, the adjusted locomotive control levels being adapted to maintain the target train speed profile over the future period; f)

Abstract: A device for the delivery of an agent to an intestinal site has a backing element, a mucoadhesive element for adhering the device to the intestinal site, and a reservoir comprising the agent. The mucoadhesive element includes a polymer, an opposing surface having the capacity to adhere to the intestinal site, and a population of passageway(s) extending from the reservoir to the opposing surface for delivery of the agent from the reservoir to the intestinal site, each of the passageway(s) having a minimum diameter greater than 10 microns, the diameter being determined by cryogenic scanning electron microscopy after 30 minutes of hydration at 20° C. in phosphate buffered saline at pH 6.5.

Abstract: Providing a technology enabled communications pathway between health care providers and patients, comprising: receiving a bio-metric telemetry data set from a patient, receiving a medication adherence data set from the patient, notifying a health care provider system of at least one potential alarm based on the bio-metric telemetry data set and the medication adherence data set, notifying the patient utilizing positive feedback of the bio-metric telemetry data set and the medication adherence data set, wherein the positive feedback is an affirming communication from the health care provider system indicating that the medication adherence has a positive feedback result in the bio-metric telemetry, notifying the patient of a health care appointment and indicating the positive feedback result the medication adherence has had in the bio-metric telemetry and providing the health care provider system a summary of bio-metric telemetry data set, medication adherence data set and positive feedback prior to the health

Abstract: A device for the delivery of an agent to an intestinal site has a backing element, a mucoadhesive element for adhering the device to the intestinal site, and a reservoir comprising the agent. The mucoadhesive element includes a polymer, an opposing surface having the capacity to adhere to the intestinal site, and a population of passageway(s) extending from the reservoir to the opposing surface for delivery of the agent from the reservoir to the intestinal site, each of the passageway(s) having a minimum diameter greater than 10 microns, the diameter being determined by cryogenic scanning electron microscopy after 30 minutes of hydration at 20° C. in phosphate buffered saline at pH 6.5.

Abstract: Methods are described for selecting or producing a cereal plant comprising a functional restorer gene for wheat G-type cytoplasmic male sterility and nucleic acids and/or polypeptides for use therein.

Abstract: Methods are described for selecting or producing a cereal plant comprising a functional restorer gene for wheat G-type cytoplasmic male sterility and nucleic acids and/or polypeptides for use therein.

Abstract: A device for the delivery of an agent to an intestinal site has a backing element, a mucoadhesive element for adhering the device to the intestinal site, and a reservoir comprising the agent. The mucoadhesive element includes a polymer, an opposing surface having the capacity to adhere to the intestinal site, and a population of passageway(s) extending from the reservoir to the opposing surface for delivery of the agent from the reservoir to the intestinal site, each of the passageway(s) having a minimum diameter greater than 10 microns, the diameter being determined by cryogenic scanning electron microscopy after 30 minutes of hydration at 20° C. in phosphate buffered saline at pH 6.5.

Abstract: The present invention relates to the field of agriculture. In particular the invention provides a protein, a nucleic acid, a recombinant gene, plants comprising the recombinant gene and methods for altering the number of spikelets per spike of a wheat plant.