Patents by Inventor Colin Robinson

Colin Robinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10457948
    Abstract: The present invention resides in a method for the manufacture of a disulphide-requiring biopharmaceutical having an element of at least tertiary structure using wild type E. coli.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: October 29, 2019
    Assignee: University of Kent
    Inventor: Colin Robinson
  • Publication number: 20170321221
    Abstract: The present invention resides in a method for the manufacture of a disulphide-requiring biopharmaceutical having an element of at least tertiary structure using wild type E. coli.
    Type: Application
    Filed: November 6, 2015
    Publication date: November 9, 2017
    Inventor: Colin ROBINSON
  • Patent number: 9439837
    Abstract: The present invention relates to a photosensitive composition comprising synthetic nanocrystalline hydroxyapatite or a synthetic precursor thereof doped with a rare earth ion, the use of the composition in restorative or cosmetic dentistry, a process for preparing the composition and a method of generating an image of an exposed dentinal surface of a tooth.
    Type: Grant
    Filed: October 10, 2011
    Date of Patent: September 13, 2016
    Assignees: University of Leeds, The University Court of the University of St. Andrews
    Inventors: Wilson Sibbett, Christian Thomas Alcuin Brown, Animesh Jha, Steven John Milne, Colin Robinson, Mandeep Singh Duggal, Kyriacos Jack Toumba
  • Publication number: 20150037842
    Abstract: The disclosure relates to a Gram negative bacterial cell that is transformed with a nucleic acid molecule that encodes a Gram positive twin-arginine translocase and including methods for the production of polypeptides.
    Type: Application
    Filed: February 22, 2013
    Publication date: February 5, 2015
    Inventor: Colin Robinson
  • Publication number: 20130260341
    Abstract: The present invention relates to a photosensitive composition comprising synthetic nanocrystalline hydroxyapatite or a synthetic precursor thereof doped with a rare earth ion, the use of the composition in restorative or cosmetic dentistry, a process for preparing the composition and a method of generating an image of an exposed dentinal surface of a tooth.
    Type: Application
    Filed: October 10, 2011
    Publication date: October 3, 2013
    Inventors: Wilson Sibbett, Christian Thomas Alcuin Brown, Animesh Jha, Steven John Milne, Colin Robinson, Mandeep Singh Duggal, Kyriacos Jack Toumba
  • Publication number: 20070015205
    Abstract: The present invention relates, inter alia, to the crystal structures of a phosphodiesterase 5 (PDE5) and PDE5/PDE5 ligand complex and their uses in identifying PDE5 ligands, including PDE5 inhibitor compounds. The present invention also relates to methods of identifying such PDE5 inhibitor compounds and their medical use. Also contemplated by the present invention are crystals of PDE5/PDE5 inhibitor complexes.
    Type: Application
    Filed: October 24, 2002
    Publication date: January 18, 2007
    Inventors: David Brown, Colin Groom, Andrew Hopkins, Timothy Jenkins, Sarah Kamp, Margaret O'Gara, Heather Ringrose, Colin Robinson, Wendy Taylor
  • Publication number: 20050202549
    Abstract: The present invention relates to the soakable crystals of a phosphodiesterase 5 (PDE5) and their uses in identifying PDE5 ligands, including PDE5 ligands and inhibitor compounds. The present invention also relates to methods of identifying such PDE5 inhibitor compounds and their medical use. The present invention additionally relates to crystals of PDE5 into which ligands may be soaked and crystals of PDE5 comprising PDE5 ligands that have been soaked into the crystal.
    Type: Application
    Filed: April 30, 2004
    Publication date: September 15, 2005
    Inventors: David Brown, Colin Groom, Andrew Hopkins, Timothy Jenkins, Sarah Kamp, Margaret O'Gara, Heather Ringrose, Colin Robinson, Wendy Taylor
  • Patent number: 4943632
    Abstract: The invention relates to the crystalline formic acid solvate of (6R, 7R)-7-[(Z)-2-(2-Aminothiazol-4-y1)-2-(2-carboxyprop-2-oxyimino)acetamido]- 3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate dihydrochloride (ceftazidime dihydrochloride).The crystalline solvate is a useful intermediate in the preparation of forms of ceftazidime suitable for administration, e.g. the pentahydrate.
    Type: Grant
    Filed: February 3, 1989
    Date of Patent: July 24, 1990
    Assignee: Glaxo Group Limited
    Inventor: Colin Robinson
  • Patent number: 4876351
    Abstract: A process for the separation of a mixture of syn and anti oxime isomers one from the other which comprises adsorbing said mixed oxime isomers onto a non-functional macroreticular adsorption resin, and eluting said resin to yield at least one eluate fraction containing one of said isomers while being substantially free of the other of said isomers.The application of this process to the separation of syn and anti isomers of cephalosporin compounds possessing an oxime grouping in a side-chain in the 7.beta.-position, and of acids corresponding to this 7.beta.-side chain, is described.
    Type: Grant
    Filed: October 30, 1987
    Date of Patent: October 24, 1989
    Assignee: Glaxo Group Limited
    Inventors: Colin Robinson, David T. Eastlick, Audrey J. Bownass
  • Patent number: 4769450
    Abstract: A process for recovering ceftazidime from an aqueous solution containing it, said solution being at a pH in the range 2.0 to 5.5, which comprises contacting the said solution with a non-functional macroreticular resin suitable for adsorbing ceftazidime, eluting the ceftazidime and isolating it, if desired in the form of a salt or hydrate.
    Type: Grant
    Filed: June 18, 1987
    Date of Patent: September 6, 1988
    Assignee: Glaxo Group Limited
    Inventors: Thomas W. Stone, Colin Robinson, David G. Hughes
  • Patent number: 4717768
    Abstract: A process for the separation of a mixture of syn and anti oxime isomers one from the other which comprises adsorbing said mixed oxime isomers onto a non-functional macroreticular adsorption resin, and eluting said resin to yield at least one eluate fraction containing one of said isomers while being substantially free of the other of said isomers.The application of this process to the separation of syn and anti isomers of cephalosporin compounds possessing an oxime grouping in a side-chain in the 7.beta.-position, and of acids corresponding to this 7.beta.-side chain, is described.
    Type: Grant
    Filed: September 7, 1984
    Date of Patent: January 5, 1988
    Assignee: Glaxo Group Limited
    Inventors: Colin Robinson, David T. Eastlick, Audrey J. Bownass
  • Patent number: 4059573
    Abstract: N-blocked amino acids, particularly derived from natural sources such as fermentation liquors, are extractively esterified from aqueous media by treatment of the aqueous solution with a diazoalkane, e.g. diphenyldiazomethane, in the presence of a water-immiscible organic solvent. Useful applications of the process include the extractive esterification of N-blocked derivatives of cephalosporin C and desacetyl cephalosporin C from fermentation broths.
    Type: Grant
    Filed: March 30, 1976
    Date of Patent: November 22, 1977
    Assignee: Glaxo Laboratories Limited
    Inventors: Colin Robinson, Derek Walker