Patents by Inventor Colin Roderick O'Dowd

Colin Roderick O'Dowd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrimidopyrimidinones useful as Wee-1 kinase inhibitors
    Patent number: 9850247
    Abstract: The present invention relates to compounds that are useful as inhibitors of the activity of Wee-1 kinase. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: December 26, 2017
    Assignee: ALMAC HOUSE
    Inventors: Timothy Harrison, Graham Trevitt, Peter Robin Hewitt, Colin Roderick O'Dowd, Frank Burkamp, Andrew John Wilkinson, Steven D. Shepherd, Hugues Miel
  • Substituted pyrido[4,3-d]pyrimidines as Wee-1 inhibitors
    Patent number: 9714244
    Abstract: The present invention relates to compounds of formula (I) that are useful as inhibitors of the activity of Wee-1 kinase. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.
    Type: Grant
    Filed: April 11, 2014
    Date of Patent: July 25, 2017
    Assignee: ALMAC DISCOVERY LIMITED
    Inventors: Colin Roderick O'Dowd, James Samuel Shane Rountree, Frank Burkamp, Andrew John Wilkinson
  • PYRIMIDOPYRIMIDINONES USEFUL AS WEE-1 KINASE INHIBITORS
    Publication number: 20160318936
    Abstract: The present invention relates to compounds that are useful as inhibitors of the activity of Wee-1 kinase. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.
    Type: Application
    Filed: December 19, 2014
    Publication date: November 3, 2016
    Inventors: Timothy Harrison, Graham Trevitt, Peter Robin Hewitt, Colin Roderick O'Dowd, Frank Burkamp, Andrew John Wilkinson, Steven D. Shepherd, Hugues Miel
  • 2-AMINOPYRIDO[4,3-D]PYRIMIDIN-5-ONE DERIVATIVES AND THEIR USE AS WEE-1 INHIBITORS
    Publication number: 20160060258
    Abstract: The present invention relates to compounds of formula (I) that are useful as inhibitors of the activity of Wee-1 kinase. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.
    Type: Application
    Filed: April 11, 2014
    Publication date: March 3, 2016
    Inventors: Colin Roderick O'Dowd, James Samuel Shane Rountree, Frank Burkamp, Andrew John Wilkinson
  • Pharmaceutical compounds
    Patent number: 8546376
    Abstract: The invention relates to a series of compounds with particular activity as inhibitors of the serine-threonine kinase AKT. Also provided are pharmaceutical compositions comprising same as well as methods for treating cancer.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: October 1, 2013
    Assignee: Almac Discovery Limited
    Inventors: Mark Peter Bell, Timothy Harrison, Sumita Bhattacharyya, James Samuel Shane Rountree, Frank Burkamp, Stephen Price, Calum MacLeod, Richard Leonard Elliott, Phillip Smith, Toby Jonathan Blench, Colin Roderick O'Dowd, Lixin Zhang, Graham Peter Trevitt, Hazel Joan Dyke
  • AKT / PKB INHIBITORS
    Publication number: 20120309739
    Abstract: The invention relates to a series of compounds with particular activity as inhibitors of the serine-threonine kinase AKT. Also provided are pharmaceutical compositions comprising same as well as methods for treating cancer.
    Type: Application
    Filed: November 3, 2010
    Publication date: December 6, 2012
    Applicant: ALMAC DISCOVERY LIMITED
    Inventors: Mark Peter Bell, Colin Roderick O'Dowd, James Samuel Shane Rountree, Graham Peter Trevitt, Timothy Harrison, Mary Melissa McFarland
  • PHARMACEUTICAL COMPOUNDS
    Publication number: 20120238541
    Abstract: The invention relates to a series of compounds with particular activity as inhibitors of the serine-threonine kinase AKT. Also provided are pharmaceutical compositions comprising same as well as methods for treating cancer.
    Type: Application
    Filed: September 17, 2010
    Publication date: September 20, 2012
    Applicant: Almac Discovery Limited
    Inventors: Mark Peter Bell, Timothy Harrison, Sumita Bhattacharyya, James Samuel Shane Rountree, Frank Burkamp, Stephen Price, Calum MacLeod, Richard Leonard Elliott, Phillip Smith, Toby Jonathan Blench, Colin Roderick O'Dowd, Lixin Zhang, Graham Peter Trevitt, Hazel Joan Dyke