Patents by Inventor Colin Suckling

Colin Suckling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Minor groove binders
    Patent number: 8012967
    Abstract: There is provided compounds of formula (I), wherein R1, R11, R12, Qa, X, Qb, Qc, A and D have meanings given in the description, or a pharmaceutically acceptable salt or solvate thereof, which compound, salt or solvate binds to the minor groove of DNA.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: September 6, 2011
    Assignee: University of Strathclyde
    Inventors: Abedawn Khalaf, Colin Suckling, Roger Waigh
  • DNA minor groove binding compounds
    Patent number: 7700765
    Abstract: There is provided an oligopeptide compound comprising: (a) at least one nitrogen-containing basic group attached to at least one end of the oligopeptide; and (b) two or more heterocyclic monomers, at least one of which is substituted in the heterocyclic part by a branched, cyclic or part cyclic C3-5 alkyl group, or a pharmaceutically acceptable salt or solvate thereof; which compound, salt or solvate binds to the minor groove of DNA.
    Type: Grant
    Filed: December 24, 2002
    Date of Patent: April 20, 2010
    Assignee: University of Strathclyde
    Inventors: Abedawn Khalaf, Roger Waigh, Colin Suckling
  • NOVEL MINOR GROOVE BINDERS
    Publication number: 20100016311
    Abstract: There is provided compounds of formula (I), wherein R1, R11, R12, Qa, X, Qb, Qc, A and D have meanings given in the description, or a pharmaceutically acceptable salt or solvate thereof, which compound, salt or solvate binds to the minor groove of DNA.
    Type: Application
    Filed: September 28, 2007
    Publication date: January 21, 2010
    Applicant: University of Strathclyde
    Inventors: Abedawn Khalaf, Colin Suckling, Roger Waigh
  • Pteridine Derivatives as Nitric Oxide Synthase Activators
    Publication number: 20090075992
    Abstract: The present invention relates to the use of pteridine derivatives as nitric oxide synthase activators. In particular, the derivatives find use in the treatment of diseases associated with endothelial dysfunction such as cardiovascular diseases.
    Type: Application
    Filed: September 10, 2008
    Publication date: March 19, 2009
    Inventors: Roger Wadsworth, Colin Suckling, Colin Gibson
  • Dna minor groove binding compounds
    Publication number: 20070117760
    Abstract: There is provided an oligopeptide compound comprising: (a) at least one nitrogen-containing basic group attached to at least one end of the oligopeptide; and (b) two or more heterocyclic monomers, at least one of which is substituted in the heterocyclic part by a branched, cyclic or part cyclic C3-5 alkyl group, or a pharmaceutically acceptable salt or solvate thereof; which compound, salt or solvate binds to the minor groove of DNA.
    Type: Application
    Filed: December 24, 2002
    Publication date: May 24, 2007
    Applicant: UNIVERSITY OF STRATHCLYDE
    Inventors: Abedawn Khalaf, Roger Waigh, Colin Suckling
  • Compounds having serotonin 5-ht17 receptor antagonist activity and muscarinic m4 receptor agonist activity and their use in the treatment of psychotic disorders
    Publication number: 20060199978
    Abstract: The present invention relates to novel treatments for schizophrenia, based on the concept of identifying agents capable of selectively binding to the serotonin 5-HT7 and muscarinic M4 receptors and the use of such compounds in treating schizophrenia. The present invention also relates to novel amidine compounds for treating schizophrenia, a method of manufacturing such compounds, pharmaceutical formulations comprising said compounds, as well as medical uses and methods of treatment using said compounds.
    Type: Application
    Filed: March 29, 2004
    Publication date: September 7, 2006
    Inventors: Dimitrios Lizos, Clare McKerchar, John Murphy, Yasuyuki Shiigi, Colin Suckling, Hiroshi Yasumatsu, Shen-ze Zhou, Judith Pratt, Brian Morris
  • Pteridine derivatives as nitric oxide synthase activators
    Publication number: 20060194800
    Abstract: The present invention relates to the use of pteridine derivatives as nitric oxide synthase activators. In particular, the derivatives find use in the treatment of diseases associated with endothelial dysfunction such as cardiovascular diseases.
    Type: Application
    Filed: December 30, 2005
    Publication date: August 31, 2006
    Inventors: Roger Wadsworth, Colin Suckling, Colin Gibson