Patents by Inventor Colin Tinsley

Colin Tinsley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA and proteins or peptides specific of bacteria of the species, methods for obtaining them and biological applications thereof
    Patent number: 8357791
    Abstract: The DNA of the invention are characterized in that they concern the whole or part of genes, with their reading frame, to be found in Neisseria meningitidis, but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc, por A, rotamase the sequence IC1106, IgA protease, pilline, pilC, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: January 22, 2013
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Xavier Nassif, Colin Tinsley
  • Nucleic acids and polypeptides specific of the genus pathogenic strains
    Patent number: 8309100
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Grant
    Filed: February 4, 2010
    Date of Patent: November 13, 2012
    Assignees: Aventis Pasteur, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Luc Aujame, Annabelle Bouchardon, Geneviève Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnès Perrin
  • DNA AND PROTEINS OR PEPTIDES SPECIFIC OF BACTERIA OF THE NEISSERIA MENINGITIDIS SPECIES, METHODS FOR OBTAINING THEM AND BIOLOGICAL APPLICATIONS THEREOF
    Publication number: 20110313026
    Abstract: The DNA of the invention are characterised in that they concern the whole or part of genes, with their reading frame, to be found in Neisseria meningitidis, but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc, por A, rotamase the sequence IC1106, IgA protease, pilline, pilC, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.
    Type: Application
    Filed: January 20, 2011
    Publication date: December 22, 2011
    Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Xavier NASSIF, Colin Tinsley
  • NUCLEIC ACIDS AND POLYPEPTIDES SPECIFIC OF THE NEISSERIA GENUS PATHOGENIC STRAINS
    Publication number: 20100184639
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Application
    Filed: February 4, 2010
    Publication date: July 22, 2010
    Inventors: Luc AUJAME, Annabelle Bouchardon, Geneviève Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnes Perrin
  • Nucleic acids and polypeptides specific for pathogenic strains of the genus
    Patent number: 7704513
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Grant
    Filed: March 27, 2008
    Date of Patent: April 27, 2010
    Assignees: Aventis Pasteur, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Luc Aujame, Annabelle Bouchardon, Geneviève Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnès Perrin
  • DNAs AND PROTEINS OR PEPTIDES SPECIFIC TO BACTERIA OF THE SPECIES NEISSERIA MENINGITIDIS, PROCESS FOR OBTAINING THEM AND THEIR BIOLOGICAL USES
    Publication number: 20090305275
    Abstract: The DNA of the invention are characterised in that they concern the whole or pan of genes, with their reading frame, to be found in Neisseria meningitidis, but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc, por A, rotamase the sequence IC1106, IgA protease, pilline, pilc, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.
    Type: Application
    Filed: February 20, 2009
    Publication date: December 10, 2009
    Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M.)
    Inventors: Xavier NASSIF, Colin Tinsley
  • POLYNUCLEOTIDES WHICH ARE OF NATURE B2/D+ A- AND WHICH ARE ISOLATED FROM E. COLI, AND BIOLOGICAL USES OF THESE POLYNUCLEOTIDES AND OF THEIR POLYPEPTIDES
    Publication number: 20090298713
    Abstract: The present invention relates to products which are of nature B2+ A?, isolated from E. coli, and to their biological applications, in particular their medical (therapeutic, vaccine and diagnostic) and biotechnological applications. In the present application, the expression “of nature B2+ A?” is intended to mean presence at a frequency greater than 10% among the E. coli strains of group B2 of the ECOR collection, and at a frequency of less than 10% among the strains of group A of the same collection. A phylogenic determination method which makes it possible to rapidly and easily distinguish the groups A, B1, B2 and D of the E. coli species with more than 99% precision is in particular described.
    Type: Application
    Filed: February 4, 2008
    Publication date: December 3, 2009
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M), ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
    Inventors: Edouard Bingen, Stephane Bonacorsi, Olivier Clermont, Xavier Nassif, Colin Tinsley
  • NUCLEIC ACIDS AND POLYPEPTIDES SPECIFIC FOR PATHOGENIC STRAINS OF THE NEISSERIA GENUS
    Publication number: 20090155886
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Application
    Filed: March 27, 2008
    Publication date: June 18, 2009
    Inventors: Luc AUJAME, Annabelle Bouchardon, Genevieve Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnes Perrin
  • compounds and anti-infection applications thereof
    Patent number: 7422754
    Abstract: The invention provides novel Neisseria meningitides (Nm) polypeptides and polynucleotides which cover the Nm genetic diversity, and which correspond to polypeptide of Nm outer membrane and/or periplasma, and to methods for producing such Nm compounds. Also provided are anti-Nm infection, and particularly diagnostic. prophylactic and therapeutic uses thereof.
    Type: Grant
    Filed: May 14, 2004
    Date of Patent: September 9, 2008
    Assignees: Institut National de la Sante et de la Recherche Medicale (Inserm), Max-Planck Gesellschaft zur Forderung des Wissenschaften E.V.
    Inventors: Xavier Nassif, Colin Tinsley, Silke Klee, Mark Achtman, Petra Merker
  • Nucleic acids and polypeptides specific for pathogenic strains of the genus
    Patent number: 7384768
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Grant
    Filed: August 3, 2004
    Date of Patent: June 10, 2008
    Assignees: Aventis Pasteur, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Luc Aujame, Annabelle Bouchardon, Geneviève Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnès Perrin
  • DNA and proteins or peptides specific of bacteria of the species, methods for obtaining them and biological applications thereof
    Patent number: 7368556
    Abstract: The DNA of the invention are characterised in that they concern the whole or part of genes, with their reading frame, to be found in Neisseria meningitidis, but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc, por A, rotamase the sequence IC1106, IgA protease, pilline, pilC, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: May 6, 2008
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Xavier Nassif, Colin Tinsley
  • DNA and proteins or peptides specific of bacteria of the Neisseria meningitidis species, methods for obtaining them and biological applications thereof
    Publication number: 20070105225
    Abstract: The DNA of the invention are characterised in that they concern the whole or part of genes, with their reading frame, to be found in Neisseria meningitidis but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc, por A, rotamase the sequence IC1106, IgA protease, pilline, pilC, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.
    Type: Application
    Filed: December 14, 2006
    Publication date: May 10, 2007
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M.), MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DES WISSENSCHAFTEN E.V., SMITHKLINE BEECHAM
    Inventors: Xavier Nassif, Colin Tinsley
  • DNA and proteins or peptides specific of bacteria of the Neisseria meningitidis species, methods for obtaining them and biological applications thereof
    Publication number: 20070082361
    Abstract: The DNA of the invention are characterised in that they concern the whole or part of genes, with their reading frame, to be found in Neisseria meningitidis, but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc , por A, rotarmase the sequence IC1106, IgA protease, pilline, pilC, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.
    Type: Application
    Filed: December 14, 2006
    Publication date: April 12, 2007
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M), MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DES WISSENSCHAFTEN E.V., SMITHKLINE BEECHAM
    Inventors: Xavier Nassif, Colin Tinsley
  • DNAs and proteins or peptides specific to bacteria of the species Neisseria meningitidis, processes for obtaining them and their biological uses
    Patent number: 7029845
    Abstract: The DNA of the invention are characterised in that they concern the whole or part of genes, with their reading frame, to be found in Neisseria meningitidis, but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc, por A, rotamase the sequence IC1106, IgA protease, pilline, pilC, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.
    Type: Grant
    Filed: August 14, 2001
    Date of Patent: April 18, 2006
    Assignees: Institut National de la Sante et de la Recherche Medicale (I.N.S.E.R.M.), Max-Planck-Gesellschaft zur Forderung des Wessenschaften E.V., Smithkline Beecham
    Inventors: Xavier Nassif, Colin Tinsley
  • DNA and proteins or peptides specific of the Neisseria meningitidis species bacteria, method for obtaining them and their biological applications
    Publication number: 20060063167
    Abstract: The DNA of the invention are characterised in that they concern the whole or part of genes, with their reading frame, to be found in Neisseria meningitidis, but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc, por A, rotamase the sequence IC1106, IgA protease, pilline, pilC, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.
    Type: Application
    Filed: January 31, 2005
    Publication date: March 23, 2006
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M), MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DES WISSENSCHAFTEN E.V., SmithKline Beecham
    Inventors: Xavier Nassif, Colin Tinsley, Mark Achtman, Jean-Louis Ruelle, Carla Vinals, Petra Merker
  • Novel Neisseria meningitidis compounds and anti-infection applications thereof
    Publication number: 20050089527
    Abstract: The invention provides novel Neisseria meningitides (Nm) polypeptides and polynucleotides which cover the Nm genetic diversity, and which correspond to polypeptide of Nm outer membrane and/or periplasma, and to methods for producing such Nm compounds. Also provided are anti-Nm infection, and particularly diagnostic. prophylactic and therapeutic uses thereof.
    Type: Application
    Filed: May 14, 2004
    Publication date: April 28, 2005
    Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), MAX-PLANCK GESELLSCHAFT ZUR FORDERUNG DES WISSENSCHAFTEN E.V.
    Inventors: Xavier Nassif, Colin Tinsley, Silke Klee, Mark Achtman, Petra Merker
  • Nucleic acids and polypeptides specific for pathogenic strains of the Neisseria genus
    Publication number: 20050032103
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Application
    Filed: August 3, 2004
    Publication date: February 10, 2005
    Inventors: Luc Aujame, Annabelle Bouchardon, Genevieve Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnes Perrin
  • Nucleic acids and polypeptides specific of the neisseria genus pathogenic strains
    Patent number: 6835384
    Abstract: The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: December 28, 2004
    Assignees: Aventis Pasteur, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Luc Aujame, Annabelle Bouchardon, Geneviève Renauld-Mongenie, Bachra Rokbi, Xavier Nassif, Colin Tinsley, Agnès Perrin
  • Polynucleotides which are of nature B2/D+ A- and which are isolated from E. coli, and biological uses of these polynucleotides and of their polypeptides
    Publication number: 20030148324
    Abstract: The present invention relates to products which are of nature B2+ A−, isolated from E. coli, and to their biological applications, in particular their medical (therapeutic, vaccine and diagnostic) and biotechnological applications. In the present application, the expression “of nature B2+ A−” is intended to mean presence at a frequency greater than 10% among the E. coli strains of group B2 of the ECOR collection, and at a frequency of less than 10% among the strains of group A of the same collection. A phylogenic determination method which makes it possible to rapidly and easily distinguish the groups A, B1, B2 and D of the E. coli species with more than 99% precision is in particular described.
    Type: Application
    Filed: September 10, 2002
    Publication date: August 7, 2003
    Inventors: Edouard Bingen, Stephane Bonacorsi, Olivier Clermont, Xavier Nassif, Colin Tinsley
  • DNAs and proteins or peptides specific to bacteria of the species Neisseria meningitidis, processes for obtaining them and their biological uses
    Publication number: 20020164603
    Abstract: The DNA of the invention are characterised in that they concern the whole or part of genes, with their reading frame, to be found in Neisseria meningitidis, but not in Neisseria gonorrhoeae, or in Neisseria lactamica except the genes involved in the biosynthesis of the polysaccharide capsule, frp A, frp C, opc, por A, rotamase the sequence IC1106, IgA protease, pilline, pilC, transferrin binding proteins and opacity proteins. The invention also concerns the polypeptides corresponding to these DNA and the antibodies directed against these polypeptides. It is applicable in the prevention and the detection of meningococcus induced infections and meningitis.
    Type: Application
    Filed: August 14, 2001
    Publication date: November 7, 2002
    Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (I.N.S.E.R.M.)
    Inventors: Xavier Nassif, Colin Tinsley, Mark Achtman, Jean-Louis Ruelle, Carla Vinals, Petra Merker