Patents by Inventor Colin W Dykes

Colin W Dykes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR RAISING ANTIBODIES
    Publication number: 20190153075
    Abstract: The present invention generally relates to methods of generating antibodies against a species of pathogen that involve identifying the pathogen that is most genetically representative of member of pathogen species and using the identified pathogen to generate an antibody.
    Type: Application
    Filed: June 18, 2018
    Publication date: May 23, 2019
    Inventors: Colin W. Dykes, Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Meghan Norvell
  • METHODS FOR RAISING ANTIBODIES
    Publication number: 20140171340
    Abstract: The present invention generally relates to methods of generating antibodies against a species of pathogen that involve identifying the pathogen that is most genetically representative of member of pathogen species and using the identified pathogen to generate an antibody.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 19, 2014
    Applicant: NANOMR, INC.
    Inventors: Colin W. Dykes, Sergey A. Dryga, Lisa-Jo Ann Clarizia, Eddie W. Adams, Meghan Norvell
  • METHODS OF IDENTIFYING AN ORGANISM
    Publication number: 20140127686
    Abstract: This disclosure features methods of identifying an organism. In certain embodiments, the invention provides methods of distinguishing virulent and non-virulent strains of Listeria monocytogenes.
    Type: Application
    Filed: August 5, 2013
    Publication date: May 8, 2014
    Applicant: OPGEN, INC.
    Inventors: Emily B. Zentz, Colin W. Dykes, Adam M. Briska
  • Methods of characterizing small nucleic acid molecules
    Patent number: 8597879
    Abstract: The invention generally relates to methods of characterizing small nucleic acid molecules, such as plasmids or nucleic acid molecules obtained from a virus. In certain embodiments, the invention provides a method of characterizing a small circular nucleic acid molecule, the method including performing rolling circle amplification on a small circular nucleic acid molecule, thereby producing a concatamer, and generating an optical map of the concatamer, thereby characterizing the small circular nucleic acid molecule.
    Type: Grant
    Filed: October 8, 2009
    Date of Patent: December 3, 2013
    Assignee: Opgen, Inc.
    Inventors: Ronald W. Lennox, Colin W. Dykes
  • METHODS OF CHARACTERIZING SMALL NUCLEIC ACID MOLECULES
    Publication number: 20110086344
    Abstract: The invention generally relates to methods of characterizing small nucleic acid molecules, such as plasmids or nucleic acid molecules obtained from a virus. In certain embodiments, the invention provides a method of characterizing a small circular nucleic acid molecule, the method including performing rolling circle amplification on a small circular nucleic acid molecule, thereby producing a concatamer, and generating an optical map of the concatamer, thereby characterizing the small circular nucleic acid molecule.
    Type: Application
    Filed: October 8, 2009
    Publication date: April 14, 2011
    Applicant: OPGEN, INC.
    Inventors: Ronald W. Lennox, Colin W. Dykes
  • Method for identifying polymorphisms
    Patent number: 6825009
    Abstract: The present invention relates to methods for the detection of polymorphism in polynucleotides by using hybridization of fragments of segments of a polynucleotide suspected of containing a polymorphism with an oligonucleotide having a sequence complementary to a fragment identifying the polymorphism and subsequent detection of incorporated labels in the oligonucleotide-fragment duplex.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: November 30, 2004
    Assignee: Variagenics, Inc.
    Inventors: Vince P. Stanton, Jr., Jia Liu Wolfe, Tomohiko Kawate, Gregory L. Verdine, Jeffrey Olson, Colin W Dykes
  • Gene expression in yeast cells
    Patent number: 5238822
    Abstract: A transformed yeast cell containing the following DNA sequences,an HIV tat gene coding for a TAT protein,a first promoter exercising transcriptional control over the tat gene,an HIV regulatory control sequence which is responsive to the TAT protein,a pre-selected gene coding for a desired polypeptide or protein, the pre-selected gene being under the control of the HIV regulatory control sequence, anda second promoter exercising transcriptional control over the HIV regulatory control sequence and the pre-selected gene.Preferably the first and second promoters are yeast promoters, the transformed yeast cell is a S.cerevisiae cell and the HIV regulatory control sequence is a TAT responsive TAR sequence.The transformed yeast cells may be used to screen for agents that inhibit the function of TAT protein.
    Type: Grant
    Filed: February 5, 1991
    Date of Patent: August 24, 1993
    Assignee: Glaxo Group Limited
    Inventors: Colin W. Dykes, Joachim F. Ernst, Adrian N. Hobden