Patents by Inventor Colin W. Greengrass

Colin W. Greengrass has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-hydroxyaminocephalosporin antibiotics
    Patent number: 4684641
    Abstract: 7.alpha.-Hydroxyamino-7.beta.-[2-substituted-2-(acylamino)acetamido]-cephal osporin antibiotics, pharmaceutically-acceptable salts and in vivo hydrolyzable esters thereof, a method of treating susceptible infections therewith, and intermediates therefor.
    Type: Grant
    Filed: June 27, 1985
    Date of Patent: August 4, 1987
    Assignee: Pfizer Inc.
    Inventors: Colin W. Greengrass, David W. T. Hoople, Thomas T. Howarth
  • 7-Hydroxyaminocephalosporin antibiotics
    Patent number: 4684642
    Abstract: 7.alpha.-Hydroxyamino-7.beta.-[2-substituted-2-(acylamino)acetamido]cephalo sporin antibiotics, pharmaceutically-acceptable salts and in vivo hydrolyzable esters thereof, a method of treating susceptible infections therewith, and intermediates therefor.
    Type: Grant
    Filed: March 5, 1986
    Date of Patent: August 4, 1987
    Assignee: Pfizer Inc.
    Inventors: Colin W. Greengrass, David W. T. Hoople, Thomas T. Howarth
  • 4-Amino-2-piperidino-quinazolines
    Patent number: 4243666
    Abstract: Regulators of the cardiovascular system and, in particular, in the treatment of hypertension having the formula ##STR1## wherein R is lower alkyl;X, is a 3- or 4-position substituent and is --(CH.sub.2).sub.n CONR.sup.1 R.sup.2, --O(CH.sub.2).sub.n CONR.sup.1 R.sup.2 or ##STR2## wherein n is 0, 1 or 2;R.sup.1 is hydrogen or lower alkyl, andR.sup.2 is lower alkyl; lower alkenyl, lower alkynyl, phenyl, substituted phenyl, C.sub.3 -C.sub.7 cycloalkyl; lower alkyl substituted by phenyl, substituted phenyl, C.sub.3 -C.sub.7 cycloalkyl, halogen, trifluoromethyl, hydroxy, lower alkoxy, lower alkoxycarbonyl, phenoxy, substituted phenoxy or --NR.sup.3 R.sup.4 wherein R.sup.3 and R.sup.4 each represent hydrogen, lower alkyl, lower alkanoyl or lower alkylsulfonyl; with the proviso that any O, N or halogen atom in R.sup.2 is separated by at least 2 carbon atoms from the nitrogen atom to which R.sup.2 is attached; orR.sup.1 and R.sup.
    Type: Grant
    Filed: May 14, 1979
    Date of Patent: January 6, 1981
    Assignee: Pfizer Inc.
    Inventors: Simon F. Campbell, John C. Danilewicz, Colin W. Greengrass, Rhona M. Plews
  • Antihypertensive 4-amino-2-[4-(substituted-alkoxy)piperidino)]quinazolines
    Patent number: 4237138
    Abstract: Regulators of the cardiovascular system and, in particular, in the treatment of hypertension having the formula ##STR1## pharmaceutically-acceptable bioprecursors thereof, and the pharmaceutically-acceptable acid addition salts thereof; wherein each of R.sup.1 and R.sup.2 is C.sub.1-4 alkyl or --CH.sub.2 CF.sub.3 ; alk is ethylene, monophenyl substituted ethylene, mono- and dimethyl substituted ethylene or monophenylmonomethyl substituted ethylene; and R.sup.3 is hydrogen, C.sub.1-4 alkyl, C.sub.3 -C.sub.6 cycloalkyl; phenyl or substituted phenyl; and methods for their preparation.
    Type: Grant
    Filed: April 16, 1979
    Date of Patent: December 2, 1980
    Assignee: Pfizer Inc.
    Inventors: Simon F. Campbell, John C. Danilewicz, Colin W. Greengrass