Abstract: In an embodiment, an athletic garment is provided including a front panel and a rear panel, a waistband portion disposed at an upper portion of the garment, a first opening for receiving a torso of a user, a second opening for receiving a first leg of a user and a third opening for receiving a second leg of a user; and a crotch panel disposed between the front and rear panel, extending from the second opening to the third opening. The crotch panel comprises a tri-layered substrate to conceal and prevent visible staining of a fluid received therein. The tri-layered substrate may include a first layer of a first material, a second layer of a second material, and a third layer of a third material.

Abstract: Systems and methods of the present disclosure are directed to neural stimulation via non-invasive sensory stimuli. The non-invasive sensory stimuli can reduce neuroinflammation, improving synaptic plasticity and stimulating neural networking, and improving microglial-mediated clearance of cerebral insults, which would otherwise contribute to the progression of brain atrophy, by inducing synchronized gamma oscillations in at least one region of a brain in a subject. Stimulations can adjust, control or otherwise manage the frequency of the neural oscillations to provide beneficial effects to one or more cognitive states or cognitive functions of the brain, while mitigating or preventing adverse consequences on a cognitive state or cognitive function that stem from progression of brain atrophy.

Abstract: In an embodiment, an athletic garment is provided including a front panel and a rear panel, a waistband portion disposed at an upper portion of the garment, a first opening for receiving a torso of a user, a second opening for receiving a first leg of a user and a third opening for receiving a second leg of a user; and a crotch panel disposed between the front and rear panel, extending from the second opening to the third opening. The crotch panel comprises a tri-layered substrate to conceal and prevent visible staining of a fluid received therein. The tri-layered substrate may include a first layer of a first material, a second layer of a second material, and a third layer of a third material.