Patents by Inventor Colleen Ruegger

Colleen Ruegger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DUAL-ACTING PHARMACEUTICAL COMPOSITIONS BASED ON SUPERSTRUCTURES OF ANGIOTENSIN RECEPTOR ANTAGONIST/BLOCKER (ARB) AND NEUTRAL ENDOPEPTIDASE (NEP) INHIBITOR
    Publication number: 20240115536
    Abstract: Solid oral dosage forms, especially tablets, of a pharmaceutical composition comprising a supramolecular complex can be formed from a direct compression process or a compaction process such as roller compaction. Such solid oral dosage forms feature an immediate release profile that allows for fast release of the therapeutic agent. A particularly useful supramolecular complex is trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl) propionate-(S)-3?-methyl-2?-(pentanoyl{2?-(tetrazol-5-ylate)biphenyl-4?-ylmethyl}amino)butyrate]hemipentahydrate.
    Type: Application
    Filed: May 9, 2023
    Publication date: April 11, 2024
    Inventors: Suliman AL-FAYOUMI, Jiahui HU, Natrajan KUMARAPERUMAL, Alan E. ROYCE, Colleen RUEGGER, Erika A ZANNOU
  • ORGANIC COMPOUNDS
    Publication number: 20220031609
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: October 14, 2021
    Publication date: February 3, 2022
    Inventors: Tomoyuki OOMURA, Madhusudhan PUDIPEDDI, Colleen RUEGGER, Alan Edward ROYCE, Masaki SASAKI, Tokuhiro TAMURA
  • DUAL-ACTING PHARMACEUTICAL COMPOSITIONS BASED ON SUPERSTRUCTURES OF ANGIOTENSIN RECEPTOR ANTAGONIST/BLOCKER (ARB) AND NEUTRAL ENDOPEPTIDASE (NEP) INHIBITOR
    Publication number: 20210085631
    Abstract: Solid oral dosage forms, especially tablets, of a pharmaceutical composition comprising a supramolecular complex can be formed from a direct compression process or a compaction process such as roller compaction. Such solid oral dosage forms feature an immediate release profile that allows for fast release of the therapeutic agent. A particularly useful supramolecular complex is trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl) propionate-(S)-3?-methyl-2?-(pentanoyl{2?-(tetrazol-5-ylate)biphenyl-4?-ylmethyl}amino)butyrate]hemipentahydrate.
    Type: Application
    Filed: December 2, 2020
    Publication date: March 25, 2021
    Inventors: Suliman AL-FAYOUMI, Jiahui HU, Natrajan KUMARAPERUMAL, Alan E. ROYCE, Colleen RUEGGER, Erika A. ZANNOU
  • ORGANIC COMPOUNDS
    Publication number: 20200237690
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: April 3, 2020
    Publication date: July 30, 2020
    Inventors: Tomoyuki OOMURA, Madhusudhan PUDIPEDDI, Colleen RUEGGER, Alan Edward ROYCE, Masaki SASAKI, Tokuhiro TAMURA
  • ORGANIC COMPOUNDS
    Publication number: 20190175527
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: February 13, 2019
    Publication date: June 13, 2019
    Inventors: Tomoyuki OOMURA, Madhusudhan PUDIPEDDI, Colleen RUEGGER, Alan Edward ROYCE, Masaki SASAKI, Tokuhiro TAMURA
  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20170368001
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Application
    Filed: September 8, 2017
    Publication date: December 28, 2017
    Inventors: Colleen Ruegger, Michael Ambuhl
  • Organic Compounds
    Publication number: 20170290787
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: June 27, 2017
    Publication date: October 12, 2017
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura
  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20170151195
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Application
    Filed: February 14, 2017
    Publication date: June 1, 2017
    Inventors: Colleen Ruegger, Michael Ambuhl
  • Organic Compounds
    Publication number: 20160338978
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1 Preceptor modulator.
    Type: Application
    Filed: August 4, 2016
    Publication date: November 24, 2016
    Applicant: Novartis AG
    Inventors: Michael AMBUHL, Jutta BEYER, Begona CARRENO-GOMEZ, Colleen RUEGGER, Stephen VALAZZA
  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20160296481
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e. g. a compound comprising a group of formula Y.
    Type: Application
    Filed: June 15, 2016
    Publication date: October 13, 2016
    Applicant: Novartis AG
    Inventors: Colleen RUEGGER, Michael AMBUHL
  • Process for making compositions comprising sphingosine 1 phosphate (S1P) receptor modulators
    Patent number: 9399066
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: July 26, 2016
    Assignee: Novartis AG
    Inventors: Colleen Ruegger, Michael Ambuhl
  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20150165046
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Application
    Filed: February 25, 2015
    Publication date: June 18, 2015
    Applicant: Novartis AG
    Inventors: Colleen Ruegger, Michael AMBUHL
  • Organic Compounds
    Publication number: 20140255497
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: May 23, 2014
    Publication date: September 11, 2014
    Applicant: Novartis AG
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura
  • ORGANIC COMPOUNDS
    Publication number: 20140227358
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1P receptor modulator.
    Type: Application
    Filed: April 17, 2014
    Publication date: August 14, 2014
    Applicant: NOVARTIS AG
    Inventors: Michael AMBUHL, Jutta BEYER, Begona CARRENO-GOMEZ, Colleen RUEGGER, Stephen VALAZZA
  • Compositions Comprising Sphingosine 1 Phosphate (S1P) Receptor Modulators
    Publication number: 20140142192
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Application
    Filed: January 27, 2014
    Publication date: May 22, 2014
    Applicant: Novartis AG
    Inventors: Colleen RUEGGER, Michael AMBUHL
  • Compositions comprising sphingosine 1 phosphate (S1P) receptor modulators
    Patent number: 8673918
    Abstract: The present invention relates to stable compositions comprising a sphingosine 1 phosphate (S1P) receptor modulator, suitable for use as a dosage form. The S1P receptor modulators are typically sphingosine analogues, such as 2-substituted 2-amino-propane-1,3-diol or 2-amino-propanol derivatives, e.g. a compound comprising a group of formula Y.
    Type: Grant
    Filed: October 9, 2008
    Date of Patent: March 18, 2014
    Assignee: Novartis AG
    Inventors: Colleen Ruegger, Michael Ambühl
  • Organic Compounds
    Publication number: 20140011885
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: September 16, 2013
    Publication date: January 9, 2014
    Applicant: Novartis AG
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura
  • Solid pharmaceutical compositions comprising a SIP receptor agonist and a sugar alcohol
    Patent number: 8324283
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) a S1P receptor agonist; and (b) a sugar alcohol.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: December 4, 2012
    Assignees: Novartis AG, Mitsubishi Pharma Corporation
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan E Royce, Masaki Sasaki, Tokuhiro Tamura
  • ORGANIC COMPOUNDS
    Publication number: 20120288559
    Abstract: The present invention provides various pharmaceutical compositions comprising an S1P receptor modulator, e.g. an S1P receptor agonist. In one aspect, there is provided a pharmaceutical composition having a coating. In other aspects, rapid disintegrating compositions are provided. In a further aspect, a pharmaceutical composition which is free of sugar alcohols is provided. In another aspect, the invention provides a pharmaceutical composition comprising a coating comprising an S1P receptor modulator.
    Type: Application
    Filed: July 19, 2012
    Publication date: November 15, 2012
    Inventors: Michael Ambühl, Jutta Beyer, Begona Carreno-Gomez, Colleen Ruegger, Stephen Valazza
  • ORGANIC COMPOUNDS
    Publication number: 20110105620
    Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.
    Type: Application
    Filed: January 10, 2011
    Publication date: May 5, 2011
    Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura