Patents by Inventor Colleen Stack
Colleen Stack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190247176Abstract: A system for use in performing aortic valve procedures using an instrument disposed through an aortic arch includes a lubricious track positionable within the aortic arch such that a lubricious inferior surface of the track is exposed to the interior of the aortic arch. An instrument to be used in performing the valve procedure is configured to be percutaneously introduced into a femoral artery, advanced through the descending aorta and into the aortic arch, and moved into sliding contact with the lubricous inferior surface of the track. The instrument is advanceable along the lubricious surface until its distal portion is at a target site for the aortic valve procedure.Type: ApplicationFiled: April 27, 2019Publication date: August 15, 2019Applicant: Minimally Invasive Surgical Access LimitedInventors: Richard S. Stack, Richard A. Glenn, Michael S. Williams, William L. Athas, Colleen Stack
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Publication number: 20180125869Abstract: The present invention provides for methods and compositions for treating and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, functional analogue or a pharmaceutically effective salt thereof.Type: ApplicationFiled: January 8, 2018Publication date: May 10, 2018Inventors: KENNETH W. LYLES, CATHLEEN S. COLON-EMERIC, CHRISTOPHER M. O'CONNOR, RICHARD S. STACK, COLLEEN STACK
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Patent number: 9867838Abstract: The present invention provides for methods for treating and/or reducing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, functional analogue or a pharmaceutically effective salt thereof.Type: GrantFiled: September 1, 2010Date of Patent: January 16, 2018Assignee: DUKE UNIVERSITYInventors: Kenneth W. Lyles, Cathleen S. Colon-Emeric, Christopher M. O'Connor, Richard S. Stack, Colleen Stack
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Publication number: 20170065818Abstract: A neuromodulation system for treating acute heart failure syndromes includes a first catheter having a parasympathetic therapy element adapted for positioning within a first blood vessel such as a superior vena cava, and a second catheter sympathetic therapy element adapted for positioning with a second, different, blood vessel such as the pulmonary artery. The catheters comprise a system in which one of catheters is slidably disposed over the other of the catheters. The system may further be slidably disposed over a third elongate element such as a Swan-Ganz catheter positionable within a pulmonary artery, such that the Swan-Ganz may be used for monitoring parameters such as blood pressure and cardiac output during neuromodulation therapy.Type: ApplicationFiled: September 8, 2015Publication date: March 9, 2017Inventors: Terrance J. Ransbury, William E. Sanders, Richard S. Stack, Colleen Stack
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Publication number: 20160250474Abstract: An intravascular electrode system includes an intravascular lead including a spiral section, and a plurality of electrodes on the spiral section. The electrodes are positioned to form a plurality of circumferentially-spaced longitudinal electrode arrays, each longitudinal array energizable independently from the other longitudinal arrays.Type: ApplicationFiled: February 11, 2015Publication date: September 1, 2016Inventors: Richard S. Stack, Michael S. Williams, Daniel W. Fifer, Richard A. Glenn, Geoffrey A Orth, Lynn Elliott, Colleen Stack
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Patent number: 9126048Abstract: A neuromodulation system for treating acute heart failure syndromes includes a first catheter having a parasympathetic therapy element adapted for positioning within a first blood vessel such as a superior vena cava, and a second catheter sympathetic therapy element adapted for positioning with a second, different, blood vessel such as the pulmonary artery. The catheters comprise a system in which one of catheters is slidably disposed over the other of the catheters. The system may further be slidably disposed over a third elongate element such as a Swan-Ganz catheter positionable within a pulmonary artery, such that the Swan-Ganz may be used for monitoring parameters such as blood pressure and cardiac output during neuromodulation therapy.Type: GrantFiled: October 28, 2013Date of Patent: September 8, 2015Assignee: INTERVENTIONAL AUTONOMICS CORPORATIONInventors: Terrance J Ransbury, William E Sanders, Richard S Stack, Colleen Stack
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Patent number: 8972015Abstract: An intravascular electrode system includes an expandable anchor and a flexible substrate which carries at least one electrode. The anchor is positioned in a blood vessel and expanded to an expanded position to bias the electrode in contact with the vessel wall. The flexible substrate may be longitudinally withdrawn from its position between the anchor and the vessel wall without removing the anchor from the blood vessel. A second flexible substrate may be longitudinally inserted into position between the anchor and vessel wall as replacement for the first substrate.Type: GrantFiled: April 23, 2013Date of Patent: March 3, 2015Assignee: Interventional Autonomics CorporationInventors: Richard S. Stack, Michael S. Williams, Daniel W. Fifer, Richard A. Glenn, Geoffrey A Orth, Lynn Elliott, Colleen Stack
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Publication number: 20140172006Abstract: A device for facilitating use of instruments disposed through an aortic arch includes an embolic deflector having a first surface positionable in contact with a wall of an aortic arch such that a porous barrier portion of the embolic deflector covers ostia of at least the brachiocephalic and left common carotid arteries. A second surface is disposed on an opposite face from the first surface. A lubricious guide track is disposed on the second surface and extends longitudinally on the embolic deflector. The deflector and/or guide track is supported by a shaft that is extendable through a femoral artery and descending aorta to position the guide within the aortic arch. During use, the device is percutaneously introduced via the femoral artery and advanced into the aorta. The porous barrier portion of the deflector is positioned over the target ostia, and the guide track thus faces into the aortic arch.Type: ApplicationFiled: August 24, 2013Publication date: June 19, 2014Inventors: Richard S. Stack, Richard A. Glenn, Michael S. Williams, William L. Athas, Colleen Stack
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Publication number: 20140148883Abstract: An intravascular electrode system includes an expandable anchor and a flexible substrate which carries at least one electrode. The anchor is positioned in a blood vessel and expanded to an expanded position to bias the electrode in contact with the vessel wall. The flexible substrate may be longitudinally withdrawn from its position between the anchor and the vessel wall without removing the anchor from the blood vessel. A second flexible substrate may be longitudinally inserted into position between the anchor and vessel wall as replacement for the first substrate.Type: ApplicationFiled: April 23, 2013Publication date: May 29, 2014Applicant: Synecor LLCInventors: Richard S. Stack, Michael S. Williams, Daniel W. Fifer, Richard A. Glenn, Geoffrey A. Orth, Lynn Elliott, Colleen Stack
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Publication number: 20140052208Abstract: A neuromodulation system for treating acute heart failure syndromes includes a first catheter having a parasympathetic therapy element adapted for positioning within a first blood vessel such as a superior vena cava, and a second catheter sympathetic therapy element adapted for positioning with a second, different, blood vessel such as the pulmonary artery. The catheters comprise a system in which one of catheters is slidably disposed over the other of the catheters. The system may further be slidably disposed over a third elongate element such as a Swan-Ganz catheter positionable within a pulmonary artery, such that the Swan-Ganz may be used for monitoring parameters such as blood pressure and cardiac output during neuromodulation therapy.Type: ApplicationFiled: October 28, 2013Publication date: February 20, 2014Applicant: Synecor LLCInventors: Terrance J Ransbury, William E Sanders, Richard S Stack, Colleen Stack
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Patent number: 8428730Abstract: A transvascular electrode system includes an expandable electrode-carrying anchor. The anchor is intravascularly advanced in a compressed position to a first site in a blood vessel. A first portion of the anchor expands to position an electrode against the vessel wall, while a second portion remains is compressed. Mapping is performed by delivering stimulation energy from the electrode and measuring the response (e.g. blood pressure, heart rate, and/or related parameters). The first portion is at least partially collapsed and the electrode system is moved to a second site. The first portion is expanded to position the electrode into against the vessel wall, while the second portion remains compressed. Additional mapping is performed. The process is repeated until the anchor electrode position is optimized, at which point the second portion of the anchor is expanded to chronically retain the electrode in the vessel.Type: GrantFiled: November 1, 2011Date of Patent: April 23, 2013Assignee: Synecor LLCInventors: Richard S. Stack, Michael S. Williams, Daniel W. Fifer, Richard A. Glenn, Geoffrey A. Orth, Lynn Elliott, Colleen Stack N'diaye
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Patent number: 8369954Abstract: Methods and systems are disclosed for stimulating contents of the carotid sheath using an intravascular pulse generator and lead. The lead carries an energy delivery device such as an electrode, which is anchor within the portion of the internal jugular vein that is disposed within the carotid sheath. The energy delivery device is energized to transvenously direct energy to target contents of the carotid sheath external to the internal jugular vein. Such target contents may include nervous system elements associated with the carotid sinus baroreceptors, the carotid sinus nerve and associated nerve branches, and or the vagus nerve and associated nerve branches. The system may be used to control blood pressure and/or to lower heart rate and may be suitable for treatment of hypertension, heart failure, or other conditions.Type: GrantFiled: March 7, 2011Date of Patent: February 5, 2013Assignee: Synecor LLCInventors: Richard S. Stack, Michael S. Williams, Daniel W. Fifer, Richard A. Glenn, Geoffrey A. Orth, Lynn Elliott, Colleen Stack N'diaye
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Publication number: 20120221014Abstract: A transvascular electrode system includes an expandable electrode-carrying anchor. The anchor is intravascularly advanced in a compressed position to a first site in a blood vessel. A first portion of the anchor expands to position an electrode against the vessel wall, while a second portion remains is compressed. Mapping is performed by delivering stimulation energy from the electrode and measuring the response (e.g. blood pressure, heart rate, and/or related parameters). The first portion is at least partially collapsed and the electrode system is moved to a second site. The first portion is expanded to position the electrode into against the vessel wall, while the second portion remains compressed. Additional mapping is performed. The process is repeated until the anchor electrode position is optimized, at which point the second portion of the anchor is expanded to chronically retain the electrode in the vessel.Type: ApplicationFiled: November 1, 2011Publication date: August 30, 2012Inventors: Richard S. Stack, Michael S. Williams, Daniel W. Fifer, Richard A. Glenn, Geoffrey A. Orth, Lynn Elliott, Colleen Stack N'diaye
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Publication number: 20120208786Abstract: The present invention provides for methods and compositions for treating and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, functional analogue or a pharmaceutically effective salt thereof.Type: ApplicationFiled: September 1, 2010Publication date: August 16, 2012Inventors: Kenneth W. Lyles, Cathleen S. Colon-Emeric, Christopher M. O'Connor, Richard S. Stack, Colleen Stack
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Publication number: 20120059431Abstract: The present disclosure describes intravascular systems that may be used for a variety of functions. The elements of the disclosed systems include at least one device body implanted within the vasculature. Electrodes on a lead and/or on the device body itself are used to direct electrical energy to neurological targets. These systems may additionally include one or more fluid reservoirs housing drugs or other agents to be delivered to tissue.Type: ApplicationFiled: November 10, 2011Publication date: March 8, 2012Inventors: Michael S. Williams, Richard S. Stack, Lynn Elliott, Colleen Stack N'diaye, Daniel W. Fifer
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Patent number: 8116883Abstract: The present disclosure describes intravascular systems that may be used for a variety of functions. The elements of the disclosed systems include at least one device body implanted within the vasculature. Electrodes on a lead and/or on the device body itself are used to direct electrical energy to neurological targets. These systems may additionally include one or more fluid reservoirs housing drugs or other agents to be delivered to tissue.Type: GrantFiled: February 2, 2007Date of Patent: February 14, 2012Assignee: Synecor LLCInventors: Michael S. Williams, Richard S. Stack, Lynn Elliott, Colleen Stack N'diaye, Daniel W. Fifer
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Publication number: 20110166482Abstract: Methods and systems are disclosed for stimulating contents of the carotid sheath using an intravascular pulse generator and lead. The lead carries an energy delivery device such as an electrode, which is anchor within the portion of the internal jugular vein that is disposed within the carotid sheath. The energy delivery device is energized to transvenously direct energy to target contents of the carotid sheath external to the internal jugular vein. Such target contents may include nervous system elements associated with the carotid sinus baroreceptors, the carotid sinus nerve and associated nerve branches, and or the vagus nerve and associated nerve branches. The system may be used to control blood pressure and/or to lower heart rate and may be suitable for treatment of hypertension, heart failure, or other conditions.Type: ApplicationFiled: March 7, 2011Publication date: July 7, 2011Inventors: Richard S. Stack, Michael S. Williams, Daniel W. Fifer, Richard A. Glenn, Geoffrey A. Orth, Lynn Elliott, Colleen Stack N'diaye
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Publication number: 20110130709Abstract: Methods of iontophoretically delivering therapeutic agents to diseased tissue, such as for tumor therapy, are disclosed. In one embodiment, the distal end of an endoscopic device is transorally introducing into the gastro-intestinal tract. A delivery element is advanced from the endoscopic device through a wall of the gastro-intestinal tract and into an adjacent pancreas. A therapeutic agent is delivered from the delivery element into the pancreas, an electric field is generated to drive the emitted therapeutic agent into surrounding tissue of the pancreas, causing the emitted agent to penetrate the surrounding tissue.Type: ApplicationFiled: May 28, 2010Publication date: June 2, 2011Inventor: Colleen Stack N'diaye
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Patent number: 7925352Abstract: Methods and systems are disclosed for stimulating contents of the carotid sheath using an intravascular pulse generator and lead. The lead carries an energy delivery device such as an electrode, which is anchor within the portion of the internal jugular vein that is disposed within the carotid sheath. The energy delivery device is energized to transvenously direct energy to target contents of the carotid sheath external to the internal jugular vein. Such target contents may include nervous system elements associated with the carotid sinus baroreceptors, the carotid sinus nerve and associated nerve branches, and or the vagus nerve and associated nerve branches. The system may be used to control blood pressure and/or to lower heart rate and may be suitable for treatment of hypertension, heart failure, or other conditions.Type: GrantFiled: March 27, 2009Date of Patent: April 12, 2011Assignee: Synecor LLCInventors: Richard S. Stack, Michael S. Williams, Daniel W. Fifer, Richard A. Glenn, Geoffrey A. Orth, Lynn Elliott, Colleen Stack N'diaye
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Publication number: 20100023088Abstract: Methods and systems are disclosed for stimulating contents of the carotid sheath using an intravascular pulse generator and lead. The lead carries an energy delivery device such as an electrode, which is anchor within the portion of the internal jugular vein that is disposed within the carotid sheath. The energy delivery device is energized to transvenously direct energy to target contents of the carotid sheath external to the internal jugular vein. Such target contents may include nervous system elements associated with the carotid sinus baroreceptors, the carotid sinus nerve and associated nerve branches, and or the vagus nerve and associated nerve branches. The system may be used to control blood pressure and/or to lower heart rate and may be suitable for treatment of hypertension, heart failure, or other conditions.Type: ApplicationFiled: March 27, 2009Publication date: January 28, 2010Inventors: Richard S. Stack, Michael S. Williams, Daniel W. Fifer, Richard A. Glenn, Geoffrey A. Orth, Lynn Elliott, Colleen Stack N'diaye