Abstract: The present disclosure provides methods of treating subjects having liver disease, and methods of identifying subjects having an increased risk of developing liver disease.

Abstract: A lock delivery system is disclosed. The lock mechanism is reversible between an unlocked configuration and a locked configuration. The lock mechanism may comprise a casing, and a first body and a second body arranged spaced-apart in the casing. The first body may comprise a first gripping portion extending to a first actuating arm, and a first spring arranged spaced-apart from the first actuating arm. The second body may comprise a second gripping portion extending to a second actuating arm, and a second spring arranged spaced-apart from the second actuating arm. The first and second bodies are each pivotable about a respective first pivot point and second pivot point so as to move the lock mechanism between an unlocked configuration and a locked configuration. A lock delivery catheter may be used as a means to move the lock mechanism between the unlocked configuration and the locked configuration.

Abstract: One or more aspects of the present disclosure relate to relate to analyzing and mitigation storage array latency. In embodiments, an input/output (IO) workload is received by a storage array. Additionally, a latency corresponding to processing one or more IO requests of the IO workload is determined. For example, a factor corresponding to a significant portion of the latency is identified. Further, a remediation action is performed based on the factor identified.

Abstract: One or more aspects of the present disclosure relate to relate to analyzing and mitigation storage array latency. In embodiments, an input/output (IO) workload is received by a storage array. Additionally, a latency corresponding to processing one or more IO requests of the IO workload is determined. For example, a factor corresponding to a significant portion of the latency is identified. Further, a remediation action is performed based on the factor identified.

Abstract: The present disclosure provides methods of treating subjects having liver disease, and methods of identifying subjects having an increased risk of developing liver disease.

Abstract: An activation function in a neural network may be approximated by one or more linear functions. A linear function may correspond to a segment of the input range of the activation function, e.g., a linear segment. A programmable look-up table may store slopes and intercepts of linear functions. A post processing engine (PPE) array executing the activation function may determine that an input data element of the activation function falls into the linear segment and compute an output of the linear function using the input data element. The output of the linear function may be used as the approximated output of the activation function. Alternatively, the PPE array may determine that the input data element is in a saturation segment and use a fixed value associated with the saturation segment as the approximated output of the activation function.

Abstract: A lock delivery system is disclosed. The lock mechanism is reversible between an unlocked configuration and a locked configuration. The lock mechanism may comprise a casing, and a first body and a second body arranged spaced-apart in the casing. The first body may comprise a first gripping portion extending to a first actuating arm, and a first spring arranged spaced-apart from the first actuating arm. The second body may comprise a second gripping portion extending to a second actuating arm, and a second spring arranged spaced-apart from the second actuating arm. The first and second bodies are each pivotable about a respective first pivot point and second pivot point so as to move the lock mechanism between an unlocked configuration and a locked configuration. A lock delivery catheter may be used as a means to move the lock mechanism between the unlocked configuration and the locked configuration.

Abstract: Storage objects are mapped to host applications in a storage domain. Each of the storage objects is analyzed to determine importance in terms of predetermined criteria such as quality of service of the storage object, replication level of the storage object, size of the storage object, input-output loading of the storage object, and input-output loading of a host application that uses the storage object. Storage objects that satisfy predetermined importance characteristics are automatically tagged with the name of the host application that uses the storage object. The storage objects may also be tagged with the names of data structures that satisfy predetermined importance characteristics. Storage groups, masking views, and volume devices may also be tagged.

Abstract: The present invention relates to a method of preparing a ready-to-consume food product. The ready-to-consume food product can be a ready-to-consume beverage, or the ready-to-consume food product can be used as a food supplement that can be incorporated, or used in the preparation of, a food item. The ready-to-consume food product provides the taste of and mouthfeel of a high fat ready-to-consume food product but has a lower fat content, so that the consumer has an increased perception of a creamy taste and texture of the food product.

Abstract: The present invention relates to a device for use in the delivery of an active agent. Specifically, the present invention relates to a device comprising a scaffold that can be formed from a polymer or copolymer; a matrix; and at least one active agent. The device finds utility in the delivery of at least one active agent, and is useful in methods of reducing cell infiltration, inflammation and collagen deposition in a tissue or treating fibrosis in a tissue. In an aspect, the device can alleviate post-operative inflammation and/or fibrosis; and can also improve patient compliance for effective delivery of an active agent.

Abstract: Semiconductor devices comprising: a semiconductor device comprising: a first electrode comprising conductive material, wherein the conductive material is deposited by ink deposition (for example, layered material inks such as graphene and/or graphite), or wherein the conductive material comprises CVD grown graphene or carbon nanotubes; a first charge transportation layer, wherein the first charge transportation layer is doped with the conductive material of the first electrode; an optional insulation layer; a perovskite active layer; a second charge transportation layer; and a second electrode.

Abstract: The present disclosure provides methods of treating subjects having liver disease, and methods of identifying subjects having an increased risk of developing liver disease.

Abstract: A process for producing pure lactic acid from a whey by-product rich in lactose and minerals, for example delactosed why permeate or concentrated whey permeate, is described. The method comprises upstream steps of neutralising the whey by-product with a basic metal hydroxide to form a precipitate comprising calcium and phosphate, and separating the precipitate from the whey by-product to provide a clarified whey by-product. The clarified whey by-product is fermentated by a bacterium capable of bioconversion of lactose to lactic acid to provide a fermentation broth containing a lactic acid salt. In the downstream steps, the fermentation broth is acidified to release lactic acid from the lactic acid salt, precipitate from the broth produced by acidification is removed, and the acidified fermentation broth is treated to recover pure lactic acid by removal of residual salts, and water, and optionally protein.

Abstract: A radiation system configured to produce radiation and comprising a droplet generator (3) configured to produce a droplet of fuel traveling towards a plasma formation region, a laser system operative to generate a pre-pulse (PP) and a main pulse (MP), wherein the pre-pulse is configured to condition the droplet for receipt of the main pulse, and wherein the main pulse is configured to convert the conditioned droplet into plasma producing the radiation and a control system configured to control a spatial offset between the pre-pulse and the droplet in a plane transverse to a propagation direction of the pre-pulse, wherein the control system is configured to adjust the spatial offset so as to maximize a velocity change of the conditioned droplet in a plane transverse to a propagation direction of the main pulse.

Abstract: The invention provides plastic 3D printed battery cell comprising a first layer coupled with a cathode material and a second layer coupled with an anode material. An aqueous electrolyte gel material is deposited onto the surface of the cathode material and the anode material, wherein the first and second layers are sealed to house the cathode material, the anode material and the electrolyte gel material. The invention provides a combination of a customisable plastic battery cell design using 3D printing with an all-in-one gel electrolyte enable the cells to be built in a variety of sizes and shapes allowing for greater integration of energy storage into electronic, medical or wearable systems. A method for making the 3D printed battery cell is also described.

Abstract: A method for producing lactic acid comprises the steps of culturing in a culture medium comprising concentrated whey permeate or delactosed whey permeate as a substrate a bioconversion competent Bacillus bacterial strain capable of converting delactosed whey permeate into lactic acid for a period of time sufficient to allow the bacteria convert at least some of the lactose present in DLP or concentrated whey permeate into lactic acid, and then recovering the lactic acid from the culture medium.

Abstract: A process for producing pure lactic acid from a whey by-product rich in lactose and minerals, for example delactosed why permeate or concentrated whey permeate, is described. The method comprises upstream steps of neutralising the whey by-product with a basic metal hydroxide to form a precipitate comprising calcium and phosphate, and separating the precipitate from the whey by-product to provide a clarified whey by-product. The clarified whey by-product is fermentated by a bacterium capable of bioconversion of lactose to lactic acid to provide a fermentation broth containing a lactic acid salt. In the downstream steps, the fermentation broth is acidified to release lactic acid from the lactic acid salt, precipitate from the broth produced by acidification is removed, and the acidified fermentation broth is treated to recover pure lactic acid by removal of residual salts, and water, and optionally protein.

Abstract: A method for producing lactic acid comprises the steps of culturing in a culture medium comprising concentrated whey permeate or delactosed whey permeate as a substrate a bioconversion competent Bacillus bacterial strain capable of converting delactosed whey permeate into lactic acid for a period of time sufficient to allow the bacteria convert at least some of the lactose present in DLP or concentrated whey permeate into lactic acid, and then recovering the lactic acid from the culture medium.

Abstract: Apparatus and methods of de-convolution for multi-phase scans of an array of electrodes are described. One programmable circuit includes a sequencer to initiate a multi-phase transmit (TX) scan of an array of electrodes to obtain capacitance data. The capacitance data is stored in one or more storage devices as convoluted capacitance data. The programmable circuit also includes a digital circuit block to read the convoluted capacitance data from the one or more storage devices, de-convolve the convoluted capacitance data to obtain de-convoluted capacitance data, and store the de-convoluted capacitance data in the one or more storage devices.

Abstract: Apparatus and methods of de-convolution for multi-phase scans of an array of electrodes are described. One programmable circuit includes a sequencer to initiate a multi-phase transmit (TX) scan of an array of electrodes to obtain capacitance data. The capacitance data is stored in one or more storage devices as convoluted capacitance data. The programmable circuit also includes a digital circuit block to read the convoluted capacitance data from the one or more storage devices, de-convolve the convoluted capacitance data to obtain de-convoluted capacitance data, and store the de-convoluted capacitance data in the or more storage devices.