Abstract: In alternative embodiments, provided are methods and products of manufacture for photoacoustic imaging of the periodontium of individuals in need thereof for noninvasive periodontal probing depth measurements and periodontal pocket imaging and gingival thickness. In alternative embodiments, products of manufacture as provided herein can observe or measure soft tissue contrast, e.g., gums, the periodontium, or the oral mucosa can be imaged and/or measured.