Abstract: A method for controlling a virtual object to mark a virtual item is provided. The method includes: displaying a virtual environment picture, the virtual environment picture including the virtual object and the virtual item in a virtual environment; controlling the virtual object to move, in the virtual environment, into a proximity range of the virtual item; displaying a pick-up item list on the virtual environment picture, a field of the virtual item available for pick-up being displayed in the pick-up item list; and receiving a mark operation on the field of the virtual item, and marking the virtual item in the virtual environment according to the mark operation, the mark operation being an operation different from a pick-up operation.

Abstract: The disclosure provides compositions and methods related to activating alpha-kinase 1 (ALPK1) for modulating an immune response and treating or preventing cancer, infection, inflammation and related diseases and disorders as well as potentiating an immune response to a target antigen. The disclosure also provides heterocyclic compounds of formula (I) as agonists of alpha protein kinase 1 (ALPK1) and their use in activating ALPK1, modulating an immune response and treating diseases such as cancer, wherein A1, A2, L1, L2, L3, Z1, Z2, W1, W2, R1, R2, R3, R4, R5, R6 and R7 are defined herein.

Abstract: Provided are compounds of Formula (I) or (II) and related compositions and methods for their use as inhibitors of alpha-kinase 1 (ALPK1).

Abstract: Provided are compounds of Formula I, compositions and methods for their use as inhibitors of alpha-kinase 1 (ALPK1).

Abstract: An automatic loading system for an extraction strip includes: an extraction strip for holding several reagents, a first channel, a second channel parallel to and attached to the first channel, a first hand pushing device for pushing the extraction strip to move in the first channel, a second hand pushing device for pushing the extraction strip to move in the second channel, and a transfer device for transferring the extraction strip from the first channel to the second channel. One end of the first channel is a loading inlet of the extraction strip. One end of the second channel is a grabbing position of the extraction strip. The transfer device is arranged at the other ends of the first channel and the second channel. The first hand pushing device and the second hand pushing device can move transversely and move up and down.

Abstract: A cartridge preprocessing system applied to an automated molecular diagnostics instrument is provided. The cartridge preprocessing system includes a piercing device and a cleaning device. The piercing device includes a drive assembly and a piercing member, and the drive assembly is configured to control the piercing member to alternately move to a piercing station and a cleaning station. The piercing member is configured to pierce a barrier film of a cartridge that moves to the piercing station, and the cleaning device is configured to clean the piercing member that moves to the cleaning station.

Abstract: A lifting/lowering underframe and a load-bearing device having same. The lifting/lowering underframe comprises a lifting/lowering mechanism (2) which comprises a first lifting/lowering frame (21), a second lifting/lowering frame (22) and a driving member (23). The two ends of the driving member (23) are connected to the first lifting/lowering frame (21) and the second lifting/lowering frame (22) respectively; the driving member (23) is an electric push rod, and the driving member (23) kept between the first lifting/lowering frame (21) and the second lifting/lowering frame (22) can electrically drive the first lifting/lowering frame (21) and the second lifting/lowering frame (22) to move relative to each other. The lifting/lowering mechanism (2) is easy to maintain, has low noise and can work normally in high/low temperature and anticorrosion/explosion-proof harsh environments.

Abstract: The present application relates to a luminescent material and a preparation method thereof. The luminescent material having a chemical formula of M1-x-y-zNbO3:xPr,yEr, where M is alkali metal element, 0.001?x?0.05, 0.001?y?0.1, and ?0.05?z?0.05. The luminescent material is a dual-lifetime (fluorescence and long-lasting luminescence) and colorful (red, orange, yellow, yellow green and green) renewable luminescent material that respond to multiple stimulation (heat, force and light), and has a characteristic of multidimensional identifiability such as excitation mode, luminescence lifetime and luminescence color.

Abstract: The present application relates to a luminescent material and a preparation method thereof. The luminescent material having a chemical formula of M1-x-y-zNbO3:xPr,yEr, where M is alkali metal element, 0.001?x?0.05, 0.001?y?0.1, and ?0.05?z?0.05. The luminescent material is a dual-lifetime (fluorescence and long-lasting luminescence) and colorful (red, orange, yellow, yellow green and green) renewable luminescent material that respond to multiple stimulation (heat, force and light), and has a characteristic of multidimensional identifiability such as excitation mode, luminescence lifetime and luminescence color.