Patents by Inventor Congcong ZHANG

Congcong ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11959238
    Abstract: A system for a sandy soil landfill solid waste polluted river channel, includes a ground water interception and diversion system and a river channel ecological remediation system. The ground water interception and diversion system includes a water intake well arranged upstream of ground water in a landfill area, a buffer pool communicated with the water intake well, and a wastewater treatment system communicated with the buffer pool. The water intake well, the buffer pool, and the wastewater treatment system are communicated through a wastewater pipe. An electric wastewater valve and a variable frequency water pump are arranged on the wastewater pipe in sequence. The river channel ecological remediation system includes an impermeable layer arranged at a bottom of a river channel and ecological bank protections arranged on both sides of a river channel slope.
    Type: Grant
    Filed: November 24, 2023
    Date of Patent: April 16, 2024
    Assignee: Nanjing Institute of Environmental Sciences, MEE
    Inventors: Houhu Zhang, Xiaofei Yan, Jinglong Liu, Lichen Liang, Congcong Sun, Xiang Chen, Cheng Zhang
  • Patent number: 11952401
    Abstract: The present disclosure belongs to the technical field of biological products for veterinary medicine, and specifically relates to a recombinant foot-and-mouth disease virus (FMDV) with a reduced immunosuppressive activity, a preparation method and use thereof, and a recombinant vaccine strain. According to the present disclosure, it is firstly discovered that FMDV 3B protein has an immunosuppressive function, and key sites for exerting the immunosuppressive function are found. A recombinant FMDV vaccine strain with a lost immunosuppressive function in FMDV 3B protein is constructed by introducing amino acid mutations into three repeated copies of FMDV 3B protein.
    Type: Grant
    Filed: July 14, 2021
    Date of Patent: April 9, 2024
    Assignee: Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences
    Inventors: Haixue Zheng, Fan Yang, Zixiang Zhu, Xiangle Zhang, Weijun Cao, Congcong Wang, Kangli Li, Huisheng Liu, Hong Tian, Keshan Zhang, Xiangtao Liu
  • Publication number: 20240092899
    Abstract: Provided is a bispecific antibody, comprising a first antigen-binding moiety and a second antigen-binding moiety, wherein a paired domain of the first antigen-binding moiety comprises an amino acid sequence of engineered HLA-I ?3 and an amino acid sequence of engineered ?2M. Also provided are an expression method for the bispecific antibody, a polynucleotide encoding the bispecific antibody, a vector and host cell containing the polynucleotide, a pharmaceutical composition containing the bispecific antibody, a fusion protein, and a conjugate.
    Type: Application
    Filed: January 27, 2022
    Publication date: March 21, 2024
    Inventors: Liangliang WANG, Zhengping ZHANG, Congcong SUN, Rongjuan ZHAO, Yimeng LI
  • Publication number: 20230335989
    Abstract: A mesoscale data-based automatic wind turbine layout method and device. The method comprises: initially screening an input wind field region on the basis of input mesoscale wind map data by means of a wind speed limit value to obtain a first wind field region; re-screening the first wind field region on the basis of input terrain data by means of a slope limit value to obtain a second wind field region; and determining, by means of tabu search in which a target wind turbine count and the second wind field region are used as inputs, a wind turbine layout that optimizes an objective function, wherein the objective function is the sum of the annual energy production for wind turbine locations.
    Type: Application
    Filed: June 26, 2023
    Publication date: October 19, 2023
    Inventors: Chuikuan ZENG, Congcong ZHANG, Xiaolong XU
  • Publication number: 20210128615
    Abstract: The present invention pertains to methods and compounds useful in a therapy involving the administration of immune cells to a patient. The method of the invention involves the modification of cells of the immune system with agonists or antagonists of immune regulators such as Interleukin-10 (IL-10) or IL-6, in order to enhance and improve the immunological potential of the immune cells for therapy. Cells modified according to the method of the invention can be administered to a patient to support a treatment of proliferative diseases such as cancer or autoimmune disorders.
    Type: Application
    Filed: October 18, 2018
    Publication date: May 6, 2021
    Inventors: Winfried Wels, Anja Waldmann, Congcong Zhang, Manuel Kaulich
  • Publication number: 20200403179
    Abstract: An organic light-emitting diode (OLED) display panel and an OLED display device are provided. The OLED display panel, by providing an auxiliary water-oxygen barrier layer between the light-emitting functional layer and the substrate, water-oxygen can be isolated by the auxiliary water-oxygen barrier layer even through the gap between the second flexible layer and the second flexible layer and the second barrier layer, thus preventing erosion of the light-emitting functional layer and improving the water-oxygen isolation capacity of the OLED display panels. The technical problem that current active-matrix organic light-emitting diode (AMOLED) display panels, having a poor ability to isolate water-oxygen, is solved.
    Type: Application
    Filed: September 23, 2019
    Publication date: December 24, 2020
    Inventors: Kai HU, Cuiyu HAO, Boyu SU, Li HE, Congcong ZHANG
  • Publication number: 20200311835
    Abstract: A mesoscale data-based automatic wind turbine layout method and device. The method comprises: initially screening an input wind field region on the basis of input mesoscale wind map data by means of a wind speed limit value to obtain a first wind field region (S100); re-screening the first wind field region on the basis of input terrain data by means of a slope limit value to obtain a second wind field region (S200); and determining, by means of taboo search in which a target wind turbine count and the second wind field region are used as inputs, a wind turbine layout that optimizes an objective function (S300), wherein the objective function is the sum of the annual energy production for wind turbine locations.
    Type: Application
    Filed: July 27, 2018
    Publication date: October 1, 2020
    Inventors: Chuikuan ZENG, Congcong ZHANG, Xiaolong XU
  • Patent number: 10550197
    Abstract: The present invention relates to an ErbB2-specific NK-92 cell or cell line containing a lentiviral vector encoding a chimeric antigen receptor and preferably two vector integration loci in its cellular genome. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line in the prevention and/or treatment of cancer, preferably ErbB2-expressing cancers. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line as targeted cell therapeutic agent and/or for adoptive cancer immunotherapy. The present invention further relates to a method for generating an ErbB2-specific NK-92 cell or cell line as well as to a method for identifying an ErbB2-specific NK-92 cell or cell line and to the ErbB2-specific NK-92 cell or cell line obtained or identified by the methods as well as their uses.
    Type: Grant
    Filed: June 18, 2015
    Date of Patent: February 4, 2020
    Assignees: Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus, DRK-Blutspendedienst Baden-Württemberg-Hessen gGmbH
    Inventors: Winfried Wels, Kurt Schonfeld, Torsten Tonn, Manuel Grez, Congcong Zhang
  • Publication number: 20180329022
    Abstract: A method for locating an object using cluster-type magnetic field is disclosed. The method implemented on an electronic apparatus, comprises: obtaining a wireless signal and a magnetic field signal; performing a first locating for an object according to the wireless signal; and performing a second locating for the object according to the magnetic field signal in the range of the first locating. In addition, an apparatus and a system for locating an object using cluster-type magnetic field are also disclosed. Accordingly, the present invention performs a first rough locating for an object by a wireless signal and then a precise locating for the object in the range of the first locating, thus reducing the amount of calculation, lowering computational complexity and improving accuracy of locating.
    Type: Application
    Filed: July 11, 2018
    Publication date: November 15, 2018
    Inventors: Xinheng Wang, Congcong Zhang, Tao Chen
  • Publication number: 20180282427
    Abstract: The present invention relates to an ErbB2-specific NK-92 cell or cell line containing a lentiviral vector encoding a chimeric antigen receptor and preferably two vector integration loci in its cellular genome. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line in the prevention and/or treatment of cancer, preferably ErhB2-expressing cancers. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line as targeted cell therapeutic agent and/or for adoptive cancer immunotherapy. The present invention further relates to a method for generating an ErbB2-specific NK-92 cell or cell line as well as to a method for identifying au ErbB2-specific NK-92 cell or cell line and to the ErbB2-specific NK-92 cell or cell line obtained or identified by the methods as well as their uses.
    Type: Application
    Filed: February 20, 2018
    Publication date: October 4, 2018
    Applicants: CHEMOTHERAPEUTISCHES FORSCHUNGSINSTITUT GEORG-SPEYER-HAUS, DRK BLUTSPENDEDIENST BADEN-WURTTEMBERG-HESSEN GGMBH
    Inventors: Winfried Wels, Kurt Schonfeld, Torsten Tonn, Manuel Grez, Congcong Zhang
  • Patent number: 9920132
    Abstract: The present invention relates to an ErbB2-specific NK-92 cell or cell line containing a lentiviral vector encoding a chimeric antigen receptor and preferably two vector integration loci in its cellular genome. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line in the prevention and/or treatment of cancer, preferably ErbB2-expressing cancers. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line as targeted cell therapeutic agent and/or for adoptive cancer immunotherapy. The present invention further relates to a method for generating an ErbB2-specific NK-92 cell or cell line as well as to a method for identifying an ErbB2-specific NK-92 cell or cell line and to the ErbB2-specific NK-92 cell or cell line obtained or identified by the methods as well as their uses.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: March 20, 2018
    Assignees: Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus, DRK Blutspendedienst Baden-Wurttemberg-Hessen gGmbH
    Inventors: Winfried Wels, Kurt Schonfeld, Torsten Tonn, Manuel Grez, Congcong Zhang
  • Publication number: 20170283507
    Abstract: The present invention relates to an ErbB2-specific NK-92 cell or cell line containing a lentiviral vector encoding a chimeric antigen receptor and preferably two vector integration loci in its cellular genome. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line in the prevention and/or treatment of cancer, preferably ErbB2-expressing cancers. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line as targeted cell therapeutic agent and/or for adoptive cancer immunotherapy. The present invention further relates to a method for generating an ErbB2-specific NK-92 cell or cell line as well as to a method for identifying an ErbB2-specific NK-92 cell or cell line and to the ErbB2-specific NK-92 cell or cell line obtained or identified by the methods as well as their uses.
    Type: Application
    Filed: May 19, 2017
    Publication date: October 5, 2017
    Inventors: Winfried Wels, Kurt Schonfeld, Torsten Tonn, Manuel Grez, Congcong Zhang
  • Publication number: 20170129967
    Abstract: The present invention relates to an ErbB2-specific NK-92 cell or cell line containing a lentiviral vector encoding a chimeric antigen receptor and preferably two vector integration loci in its cellular genome. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line in the prevention and/or treatment of cancer, preferably ErbB2-expressing cancers. The present invention further relates to the use of the ErbB2-specific NK-92 cell or cell line as targeted cell therapeutic agent and/or for adoptive cancer immunotherapy. The present invention further relates to a method for generating an ErbB2-specific NK-92 cell or cell line as well as to a method for identifying an ErbB2-specific NK-92 cell or cell line and to the ErbB2-specific NK-92 cell or cell line obtained or identified by the methods as well as their uses.
    Type: Application
    Filed: June 18, 2015
    Publication date: May 11, 2017
    Inventors: Winfried Wels, Kurt Schonfeld, Torsten Tonn, Manuel Grez, Congcong Zhang
  • Publication number: 20170097237
    Abstract: A method for real-time object locating and mapping includes: 1) performing real-time locating for a moving object in the range of movement; 2) updating a geomagnetic field map in the range of movement of the object in real time according to the locating of the moving object; 3) locating the next position of the moving object according to the updated geomagnetic field map; and repeating steps 2) and 3) until the object stops moving. A device for real-time object locating and mapping is also disclosed. The present application can solve the problem of real-time object locating and accurate geomagnetic field mapping without an indoor priori magnetic field map.
    Type: Application
    Filed: December 16, 2016
    Publication date: April 6, 2017
    Applicant: CHIGOO INTERACTIVE TECHNOLOGY CO., LTD.
    Inventors: Xinheng WANG, Congcong ZHANG, Shangjie JIA