Abstract: The present disclosure relates to a modular, multi-fluidic, multi-nozzle system. The system may incorporate a hub having a first and second internal fluid reservoirs for holding first and second fluids. The hub has recess in flow communication with each of the first and second internal fluid reservoirs. A fluid droplet generation chip is removably secured in the recess and has first and second flow paths in communication with the first and second internal fluid reservoirs, and an opening forming an ejection port. The fluid droplet generation chip receives streams of the first and second fluids and releases the two streams simultaneously through the ejection port. In this manner double emulsion fluid droplets are created in which a quantity of the first fluid is fully encapsulated within a quantity of the second fluid.

Abstract: A composite material for gas capture including CO2 capture and capture of other gases. The composite material includes solid or liquid reactive material, filler material, and a gas-permeable polymer coating such that the reactive material forms micron-scale domains in the filler material.

Abstract: A live cell-laden microgel, in accordance with one aspect of the present invention, includes at least one live cell and a photocured resin. An in-air drop formed microgel, in accordance with one aspect of the present invention, includes a component selected from the group consisting of DNA, RNA, a protein, a peptide, an antibody, a living-cell produced catalyst, a nucleic acid-based material, a prokaryotic cell, an eukaryotic cell, and a different type of biological component.

Abstract: Aspects of this technical solution can include transporting one or more microreactors comprising one or more polypeptides and one or more putative binding partners through a channel of an interrogation chamber, capturing data corresponding to the one or more microreactors comprising the one or more polypeptides and one or more putative binding partners in the channel, determining one or more binding affinities of the one or more polypeptides to the one or more putative binding partners based on the captured data, and generating, by a machine learning model (e.g., a neural network) receiving input based on the one or more binding affinities, output indicative of one or more predicted amino acid sequences of a polypeptide.

Abstract: In accordance with one embodiment, a mixture for forming polymer-encapsulated whole cells includes: at least one polymer precursor; at least one initiator; and a plurality of whole cells. In further embodiments, a product includes a structure comprising a plurality of whole cells encapsulated by a polymer network, where polymer(s) of the polymer network are cross-linked. The whole cells may include live whole cells, dried whole cells, and/or reconstituted whole cells, and have a characteristic to convert a chemical reactant to a product, where the chemical reactant is a gas (e.g., C1-C3 carbon gases such as methane, carbon dioxide, ethane, etc.) and the product is a liquid (e.g. methanol, etc.). For example, the whole cells may include organisms such as methanotrophic organisms and/or acetogenic anaerobes.

Abstract: Fabrication of functional polymer-based particles by crosslinking UV-curable polymer drops in mid-air and collecting crosslinked particles in a solid container, a liquid suspension, or an air flow. The particles can contain different phases in the form or layered structures that contain one to multiple cores, or structures that are blended with dissolved or emulsified smaller domains. A curing system produces ultraviolet rays that are directed onto the particles in the jet stream from one side. A reflector positioned on other side of the jet stream reflects the ultraviolet rays back onto the particles in the jet stream.

Abstract: Methods of forming such microcapsules, in accordance with some embodiments, include: emulsifying at least one biocatalyst in a polymer precursor mixture; emulsifying the polymer precursor mixture in an aqueous carrier solution; crosslinking one or more polymer precursors of the polymer precursor mixture to form a plurality of microcapsules each independently comprising: a polymeric shell permeable to one or more target gases; and at least one biocatalyst disposed in an interior of the polymeric shell. In further embodiments, corresponding methods of using the inventive microcapsules for catalyzing one or more target gases using include: exposing a plurality of the biocatalytic microcapsules to the one or more target gases.

Abstract: According to one embodiment, a microcapsule for selective catalysis of gases, the microcapsule comprising: a polymeric shell permeable to one or more target gases; and at least one biocatalyst disposed in an interior of the polymeric shell. In more embodiments, methods of forming such microcapsules include: emulsifying at least one biocatalyst in a polymer precursor mixture; emulsifying the polymer precursor mixture in an aqueous carrier solution; crosslinking one or more polymer precursors of the polymer precursor mixture to form a plurality of microcapsules each independently comprising: a polymeric shell permeable to one or more target gases; and at least one biocatalyst disposed in an interior of the polymeric shell. In further embodiments, corresponding methods of using the inventive microcapsules for catalyzing one or more target gases using include: exposing a plurality of the biocatalytic microcapsules to the one or more target gases.

Abstract: A composite material for gas capture including CO2 capture and capture of other gases. The composite material includes solid or liquid reactive material, filler material, and a gas-permeable polymer coating such that the reactive material forms micron-scale domains in the filler material.

Abstract: The present disclosure relates to a nozzle system for use in a microfluidic production application for producing at least one of particles, capsules or fibers. The system has a main body portion having a compressed fluid inlet and a core fluid inlet, and a plurality of parallel arranged core fluid nozzles that receive the core fluid and create a plurality of core fluid streams. At least one compressed fluid inlet associated with the main body channels compressed fluid to areas adjacent ends of the core fluid nozzles. An apertured plate having a plurality of apertures is arranged near the ends of the core fluid nozzles, with each aperture being uniquely associated with a single one of the core fluid nozzles. The compressed fluid acts on the core fluid streams exiting the core fluid nozzles to help create, with the apertures, at least one of core fluid droplets or core fluid fibers from the core fluid streams.

Abstract: A composite material for gas capture including CO2 capture and capture of other gases. The composite material includes solid or liquid reactive material, filler material, and a gas-permeable polymer coating such that the reactive material forms micron-scale domains in the filler material.

Abstract: Fabrication of functional polymer-based particles by crosslinking UV-curable polymer drops in mid-air and collecting crosslinked particles in a solid container, a liquid suspension, or an air flow. The particles can contain different phases in the form or layered structures that contain one to multiple cores, or structures that are blended with dissolved or emulsified smaller domains. A curing system produces ultraviolet rays that are directed onto the particles in the jet stream from one side. A reflector positioned on other side of the jet stream reflects the ultraviolet rays back onto the particles in the jet stream.

Abstract: The present disclosure relates to a nozzle system for use in a microfluidic production application for producing at least one of particles, capsules or fibers. The system has a main body portion having a compressed fluid inlet and a core fluid inlet, and a plurality of parallel arranged core fluid nozzles that receive the core fluid and create a plurality of core fluid streams. At least one compressed fluid inlet associated with the main body channels compressed fluid to areas adjacent ends of the core fluid nozzles. An apertured plate having a plurality of apertures is arranged near the ends of the core fluid nozzles, with each aperture being uniquely associated with a single one of the core fluid nozzles. The compressed fluid acts on the core fluid streams exiting the core fluid nozzles to help create, with the apertures, at least one of core fluid droplets or core fluid fibers from the core fluid streams.

Abstract: Fabrication of functional polymer-based particles by crosslinking UV-curable polymer drops in mid-air and collecting crosslinked particles in a solid container, a liquid suspension, or an air flow. The particles can contain different phases in the form or layered structures that contain one to multiple cores, or structures that are blended with dissolved or emulsified smaller domains. A curing system produces ultraviolet rays that are directed onto the particles in the jet stream from one side. A reflector positioned on other side of the jet stream reflects the ultraviolet rays back onto the particles in the jet stream.

Abstract: A composition includes a plurality of microparticles, where the microparticles comprise agglomerates of nanopowder, wherein the nanopowder includes a material selected from the following: a ceramic material, a metal, an alloy, a polymer, or a combination thereof. The microparticles are characterized by having an essentially spherical shape, nanograin features substantially identical to nanograin features of the nanopowder prior to formation into the microparticles, and a nanoscale porosity defined by the nanograin features. The plurality of microparticles have an essentially uniform size relative to one another. Moreover, the composition has flowability having a Hausner Ratio representing tapped density:bulk density less than 1.25.

Abstract: A composite material for gas capture, notably CO2 capture and storage. The composite material includes a mixture of a solid or liquid reactive filler and a gas-permeable polymer such that the reactive filler forms micron-scale domains in the polymer matrix.

Abstract: A system is provided to automatically monitor and control the operation of a microfluidic device using machine learning technology. The system receives images of a channel of a microfluidic device collected by a camera during operation of the microfluidic device. Upon receiving an image, the system applies a classifier to the image to classify the operation of the microfluidic device as normal, in which no adjustment to the operation is needed, or as abnormal, in which an adjustment to the operation is needed. When an image is classified as normal, the system may make no adjustment to the microfluidic device. If, however, an image is classified as abnormal, the system may output an indication that the operation is abnormal, output an indication of a needed adjustment, or control the microfluidic device to make the needed adjustment.

Abstract: A system is provided to automatically monitor and control the operation of a microfluidic device using machine learning technology. The system receives images of a channel of a microfluidic device collected by a camera during operation of the microfluidic device. Upon receiving an image, the system applies a classifier to the image to classify the operation of the microfluidic device as normal, in which no adjustment to the operation is needed, or as abnormal, in which an adjustment to the operation is needed. When an image is classified as normal, the system may make no adjustment to the microfluidic device. If, however, an image is classified as abnormal, the system may output an indication that the operation is abnormal, output an indication of a needed adjustment, or control the microfluidic device to make the needed adjustment.

Abstract: Fabrication of functional polymer-based particles by crosslinking UV-curable polymer drops in mid-air and collecting crosslinked particles in a solid container, a liquid suspension, or an air flow. The particles can contain different phases in the form or layered structures that contain one to multiple cores, or structures that are blended with dissolved or emulsified smaller domains. A curing system produces ultraviolet rays that are directed onto the particles in the jet stream from one side. A reflector positioned on other side of the jet stream reflects the ultraviolet rays back onto the particles in the jet stream.

Abstract: A system is provided to automatically monitor and control the operation of a microfluidic device using machine learning technology. The system receives images of a channel of a microfluidic device collected by a camera during operation of the microfluidic device. Upon receiving an image, the system applies a classifier to the image to classify the operation of the microfluidic device as normal, in which no adjustment to the operation is needed, or as abnormal, in which an adjustment to the operation is needed. When an image is classified as normal, the system may make no adjustment to the microfluidic device. If, however, an image is classified as abnormal, the system may output an indication that the operation is abnormal, output an indication of a needed adjustment, or control the microfluidic device to make the needed adjustment.