Patents by Inventor Conlin O'Neil

Conlin O'Neil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXTRACELLULAR VESICLE COMPOSITIONS
    Publication number: 20240209368
    Abstract: The present disclosure relates to compositions comprising extracellular vesicles (e.g., exosomes) that can comprise an antisense oligonucleotide (ASO), wherein the composition has an osmolarity that is lower than 450 mOsm/kg. Also provided herein are methods for producing the extracellular vesicles and methods for using the extracellular vesicles to treat and/or prevent a range of medical disorders.
    Type: Application
    Filed: April 1, 2022
    Publication date: June 27, 2024
    Inventors: Conlin O'NEIL, Raymond BOURDEAU, Kimberly ELLIS, Andrew WOOD
  • EXTRACELLULAR VESICLE COMPOSITIONS
    Publication number: 20240099973
    Abstract: The present disclosure relates to compositions for the storage and administration of extracellular vesicles (e.g., exosomes) that can comprise a scaffold protein and one or more (e.g., 1, 2, 3, 4, 5 or more) exogenous biologically active moieties. Also provided herein are methods for producing the exosomes and methods for using the exosomes to treat and/or prevent a range of medical disorders.
    Type: Application
    Filed: September 25, 2020
    Publication date: March 28, 2024
    Applicant: LONZA SALES AG
    Inventors: Conlin O'NEIL, Raymond BOURDEAU
  • METHODS OF PRODUCING EXTRACELLULAR VESICLES
    Publication number: 20230103726
    Abstract: Provided herein are methods of preparing EVs, e.g., exosomes, associated with or encapsulated various cyclic dinucleotides, including STING agonists. Also provided herein are methods of loading EVs, e.g., exosomes, with various cyclic dinucleotides, including STING agonists.
    Type: Application
    Filed: September 25, 2020
    Publication date: April 6, 2023
    Applicant: Codiak BioSciences, Inc.
    Inventors: Raymond BOURDEAU, Su Chul JANG, Rane HARRISON, Conlin O'NEIL, Aaron NOYES
  • Methods for administering synthetic nanocarriers that generate humoral and cytotoxic T lymphocyte responses
    Patent number: 10933129
    Abstract: Disclosed are methods for generating humoral and cytotoxic T lymphocyte (CTL) immune responses in a subject and related compositions.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: March 2, 2021
    Assignee: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Conlin O'Neil, Petr Ilyinskii
  • POLYESTER POLYMER MATRICES FOR THE DELIVERY OF ALLERGENS
    Publication number: 20180071394
    Abstract: Provided herein are polyester polymer synthetic nanocarriers that encapsulate allergens as well as methods of their use and production.
    Type: Application
    Filed: August 24, 2017
    Publication date: March 15, 2018
    Inventors: Conlin O'Neil, Petr Ilyinskii
  • METHODS AND COMPOSITIONS RELATED TO SYNTHETIC NANOCARRIERS WITH RAPAMYCIN IN A STABLE, SUPER-SATURATED STATE
    Publication number: 20160128987
    Abstract: Disclosed are compositions and methods that provide synthetic nanocarriers that comprise hydrophobic polyester carrier material and rapamycin that is in a stable, super-saturated amount. In some embodiments, the synthetic nanocarriers are also initially sterile filterable. In other embodiments, the rapamycin is present in the synthetic nanocarrier compositions in an amount that is less than 50 weight % rapamycin/hydrophobic polyester carrier material in the composition.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 12, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventors: Conlin O'Neil, Aaron P. Griset, David H. Altreuter
  • METHODS AND COMPOSITIONS RELATED TO THE USE OF LOW HLB SURFACTANTS IN THE PRODUCTION OF SYNTHETIC NANOCARRIERS COMPRISING A RAPALOG
    Publication number: 20160128986
    Abstract: Disclosed are compositions and methods related to synthetic nanocarriers comprising a hydrophobic carrier material, a rapalog, and a non-ionic surfactant with a hydrophilic-lipophilic balance (HLB) value less than or equal to 10.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 12, 2016
    Applicant: Selecta Biosciences, Inc.
    Inventors: Conlin O'Neil, Aaron P. Griset, David H. Altreuter
  • SYNTHETIC NANOCARRIERS THAT GENERATE HUMORAL AND CYTOTOXIC T LYMPHOCYTE (CTL) IMMUNE RESPONSES
    Publication number: 20130028941
    Abstract: Disclosed are methods for generating humoral and cytotoxic T lymphocyte (CTL) immune responses in a subject and related compositions.
    Type: Application
    Filed: July 27, 2012
    Publication date: January 31, 2013
    Applicant: Selecta Biosciences, Inc.
    Inventors: David H. Altreuter, Conlin O'Neil, Petr Ilyinskii