Patents by Inventor Connie Lauritzen

Connie Lauritzen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptidyl nitril compounds as dipeptidyl peptidase I inhibitors
    Patent number: 10479781
    Abstract: The invention relates to compounds of Formula (I) and their use as selective dipeptidyl peptidase I inhibitors, as well as pharmaceutical compositions comprising said compounds, and methods of treatment involving said compounds.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: November 19, 2019
    Assignee: Neuprozyme Therapeutics APS
    Inventors: Conni Lauritzen, John Pedersen
  • PEPTIDYL NITRIL COMPOUNDS AS DIPEPTIDYL PEPTIDASE I INHIBITORS
    Publication number: 20180044328
    Abstract: The invention relates to compounds of Formula (I) and their use as selective pharmaceutical compositions comprising said compounds, and methods of treatment involving said compounds.
    Type: Application
    Filed: March 4, 2016
    Publication date: February 15, 2018
    Applicant: Prozymex A/S
    Inventors: Conni Lauritzen, John Pedersen
  • Peptidyl nitril compounds as dipeptidyl peptidase I inhibitors
    Patent number: 9856228
    Abstract: The invention relates to compounds of Formula (I) and their use as selective dipeptidyl peptidase I inhibitors, as well as pharmaceutical compositions comprising said compounds, and methods of treatment involving said compounds.
    Type: Grant
    Filed: September 8, 2014
    Date of Patent: January 2, 2018
    Assignee: PROZYMEX A/S
    Inventors: Conni Lauritzen, John Pedersen
  • RAT CATHESPIN DIPEPTIDYL PEPTIDASE I (DPPI): CRYSTAL STRUCTURE AND ITS USES
    Publication number: 20110236367
    Abstract: The present invention relates to structural studies of dipeptidyl peptidase I (DPPI) proteins, modified dipeptidyl peptidase I (DPPI) proteins and DPPI co-complexes. Included in the present invention is a crystal of a dipeptidyl peptidase I (DPPI) and corresponding structural information obtained by X-ray crystallography from rat and human DPPI. In addition, this invention relates to methods for using structure co-ordinates of DDPI, mutants hereof and co-complexes, to design compounds that bind to the active site or accessory binding sites of DPPI and to design improved inhibitors of DPPI or homologues of the enzyme.
    Type: Application
    Filed: May 20, 2010
    Publication date: September 29, 2011
    Applicant: TeleNav, Inc.
    Inventors: Johan Gotthardt OLSEN, Anders Kadziola, Søren Weis Dahl, Connie Lauritzen, Sine Larsen, John Pedersen, Dusan Turk, Marjetka Podobnik, Igor Stern
  • Dipeptidyl peptidase I crystal structure and its uses
    Patent number: 7736875
    Abstract: The present invention relates to structural studies of dipeptidyl peptidase I (DPPI) proteins, modified dipeptidyl peptidase I (DPPI) proteins and DPPI co-complexes. Included in the present invention is a crystal of a dipeptidyl peptidase I (DPPI) and corresponding structural information obtained by X-ray crystallography from rat and human DPPI. In addition, this invention relates to methods for using structure co-ordinates of DDPI, mutants hereof and co-complexes, to design compounds that bind to the active site or accessory binding sites of DPPI and to design improved inhibitors of DPPI or homologues of the enzyme.
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: June 15, 2010
    Assignee: Prozymex A/S
    Inventors: Johan Gotthardt Olsen, Anders Kadziola, Søren Weis Dahl, Connie Lauritzen, Sine Larsen, John Pedersen, Dusan Turk, Marjetka Podobnik, Igor Stern
  • Purified proenzyme of dipeptidyl peptidase i (pro-dppi)
    Publication number: 20040047853
    Abstract: The present invention relates to a substantially pure proenzyme of dipeptidyl peptidase I (pro-DPPI) and mutants thereof. The invention disclosed herein presents novel and fundamentally inventive means of producing substantially pure pro-DPPI in milligrams to gram scale quantities and of selectively purifying unprocessed pro-DPPI from mixtures of pro-DPPI and DPPI. The present invention further relates to biochemical and pharmaceutical applications of pro-DPPI and the generation of monoclonal and polyclonal antibodies against pro-DPPI and the uses thereof.
    Type: Application
    Filed: March 10, 2003
    Publication date: March 11, 2004
    Inventors: Soren W Dahl, Connie Lauritzen, John Pedersen, Boris Turk
  • Dipeptidyl peptidase i crystal structure and its uses
    Publication number: 20040043469
    Abstract: The present invention relates to structural studies of dipeptidyl peptidase I (DPPI) proteins, modified dipeptidyl peptidase I (DPPI) proteins and DPPI co-complexes. Included in the present invention is a crystal of a dipeptidyl peptidase I (DPPI) and corresponding structural information obtained by X-ray crystallography from rat and human DPPI. In addition, this invention relates to methods for using structure co-ordinates of DDPI, mutants hereof andco-complexes, to design compounds that bind to the active site or accessory binding sites of DPPI and to design improved inhibitors of DPPI or homologues of the enzyme.
    Type: Application
    Filed: August 15, 2003
    Publication date: March 4, 2004
    Inventors: Johan Gotthardt Olsen, Anders Kadziola, Soren Weis Dahl, Connie Lauritzen, Sine Larsen, John Pedersen, Susan Turk, Marietka Podobnik, Igor Stern
  • Enzymatic process for producing a desired protein from an amino terminal extended protein
    Patent number: 5783413
    Abstract: An enzymatic process is presented for producing a desired protein from an amino terminal extended protein by reaction with one or more aminopeptidases, glutamine cyclotransferase and pyroglutamine aminopeptidase.
    Type: Grant
    Filed: February 5, 1997
    Date of Patent: July 21, 1998
    Assignee: Unizyme Laboratories A/S
    Inventors: John Pedersen, Conni Lauritzen, Mads Thorup Madsen