Abstract: In some examples, a data management and storage (DMS) system comprises peer DMS nodes in a node cluster, a distributed data store comprising local and cloud storage, and an IO request scheduler comprising at least one processor configured to perform operations in a method of scheduling IO requests. Example operations comprise implementing a kernel scheduler to schedule a flow of IO requests in the DMS system, and providing an adjustment layer to adjust the kernel scheduler based on an IO request prioritization. A flow of IO requests is identified and some examples implement an IO request prioritization based on the adjustments made by the adjustment layer.

Abstract: Systems and methods are described that include receiving, in a tab strip generated by a web browser application, a request to generate a tab group, generating the tab group, in response to receiving the request, where the generating includes generating a tab group identifier for the tab group, enabling pausing or starting of an activity associated with a resource accessed by a browser tab within the tab group based on whether the tab group is collapsed or expanded, and storing metadata about the tab group and the browser tab included in the tab group. The systems and methods may further include causing display of the generated tab group in the tab strip with the tab group identifier depicted in at least a portion of a user interface associated with the browser tab where the generated tab group is configured for display based on the metadata.

Abstract: This application relates to a method of covering a pessary device for relief of female incontinence with an overwrap. More particularly, the present invention relates to methods of conforming the overwrap to the pessary device.

Abstract: A bruxism sensor includes a diaphragm switch which provides an electrical output including a diaphragm separating a pressure side having a pressure side inlet and a suction side having a suction side inlet. An audible alarm having an electrical input is coupled to the electrical output. A first hose has one end is fluidically coupled to the pressure side inlet and a biting configured opposite end (biting end) for positioning between teeth of a user. Wherein upon a contraction of a mandible of the user, the biting end is squeezed which generates air pressure that is applied to the pressure side to generate a pressure level sufficient for activating the diaphragm switch, and while the diaphragm switch is activated, the audible alarm automatically sounds an alarm for alerting the user of contraction of their mandible.

Abstract: A bruxism sensor includes a diaphragm switch which provides an electrical output including a diaphragm separating a pressure side having a pressure side inlet and a suction side having a suction side inlet. An audible alarm having an electrical input is coupled to the electrical output. A first hose has one end is fluidically coupled to the pressure side inlet and a biting configured opposite end (biting end) for positioning between teeth of a user. Wherein upon a contraction of a mandible of the user, the biting end is squeezed which generates air pressure that is applied to the pressure side to generate a pressure level sufficient for activating the diaphragm switch, and while the diaphragm switch is activated, the audible alarm automatically sounds an alarm for alerting the user of contraction of their mandible.

Abstract: The present invention relates to newly identified microorganisms capable of direct production of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also relates to polynucleotide sequences comprising genes that encode proteins which are involved in the synthesis of Vitamin C. The invention also features polynucleotides comprising the full length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. The present invention also relates to the use of said polynucleotides and polypeptides as biotechnological tools in the production of Vitamin C from microorganisms, whereby a modification of said polynucleotides and/or encoded polypeptides has a direct or indirect impact on yield, production, and/or efficiency of production of the fermentation product in said microorganism.

Abstract: This application relates to a method of covering a pessary device for relief of female incontinence with an overwrap. More particularly, the present invention relates to methods of conforming the overwrap to the pessary device.

Abstract: The present invention discloses an isolated polynucleotide molecule derived from a polynucleotide encoding a polypeptide having L-sorbosone dehydrogenase activity comprising a partial nucleotide sequence of at least 20 consecutive nucleotides of SEQ ID NO:1. The present invention further relates to a process for the production of L-ascorbic acid in high yield, in particular a process using resting cells of a microorganism able to convert given carbon sources into vitamin C. The thus obtained vitamin C may be further processed by purification and/or separation steps.

Abstract: The present invention relates to newly identified microorganisms capable of direct production of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also relates to polynucleotide sequences comprising genes that encode proteins which are involved in the synthesis of Vitamin C. The invention also features polynucleotides comprising the full length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. The present invention also relates to the use of said polynucleotides and polypeptides as biotechnological tools in the production of Vitamin C from microorganisms, whereby a modification of said polynucleotides and/or encoded polypeptides has a direct or indirect impact on yield, production, and/or efficiency of production of the fermentation product in said microorganism.

Abstract: The present invention relates to newly identified microorganisms capable of direct production of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also relates to polynucleotide sequences comprising genes that encode proteins which are involved in the synthesis of Vitamin C. The invention also features polynucleotides comprising the full length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. The present invention also relates to the use of said polynucleotides and polypeptides as biotechnological tools in the production of Vitamin C from microorganisms, whereby a modification of said polynucleotides and/or encoded polypeptides has a direct or indirect impact on yield, production, and/or efficiency of production of the fermentation product in said microorganism.

Abstract: The present invention discloses an isolated polynucleotide molecule derived from a polynucleotide encoding a polypeptide having L-sorbosone dehydrogenase activity comprising a partial nucleotide sequence of at least 20 consecutive nucleotides of SEQ ID NO:1. The present invention further relates to a process for the production of L-ascorbic acid in high yield, in particular a process using resting cells of a microorganism able to convert given carbon sources into vitamin C. The thus obtained vitamin C may be further processed by purification and/or separation steps.

Abstract: The present invention discloses an isolated polynucleotide molecule derived from a polynucleotide encoding a polypeptide having L-sorbosone dehydrogenase activity comprising a partial nucleotide sequence of at least 20 consecutive nucleotides of SEQ ID NO:1. The present invention further relates to a process for the production of L-ascorbic acid in high yield, in particular a process using resting cells of a microorganism able to convert given carbon sources into vitamin C. The thus obtained vitamin C may be further processed by purification and/or separation steps.

Abstract: The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. The present invention also relates to the use of said polynucleotides and polypeptides as biotechnological tools in the production of Vitamin C from microorganisms, whereby a modification of said polynucleotides and/or encoded polypeptides has a direct or indirect impact on yield, production, and/or efficiency of production of the fermentation product in said microorganism. Also included are methods/processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms.

Abstract: The present invention discloses an isolated polynucleotide molecule derived from a polynucleotide encoding a polypeptide having L-sorbosone dehydrogenase activity comprising a partial nucleotide sequence of at least 20 consecutive nucleotides of SEQ ID NO:1. The present invention further relates to a process for the production of L-ascorbic acid in high yield, in particular a process using resting cells of a microorganism able to convert given carbon sources into vitamin C. The thus obtained vitamin C may be further processed by purification and/or separation steps.