Abstract: The present invention relates to methods to treat dry eye in a mammal by intraocularly administering a composition comprising a peptide.

Abstract: The present invention features compositions comprising at least one compound of the formula I or formula II: wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, or a cosmetically acceptable salt thereof, and the use thereof for darkening the skin.

Abstract: The present invention features polymers containing vanillin monomers and/or o-vanillin monomers and the use thereof in darkening the skin.

Abstract: A controller system for a CD-ROM drive or other slow access device such as a magneto-optical device using a conventional hard disk drive as a cache memory. In some embodiments, the hard disk cache is partitioned to use a portion thereof to clone the most often used data blocks on the CD-ROM disk such as the directory/file allocation table, while the balance of the hard disk is used to cache some or all of the balance of the CD-ROM disk using conventional cache memory least recently used rules. Three bus controllers for the host computer, CD-ROM drive and the hard disk cache are controlled by a microprocessor which runs a control program that implements the cloning and cache rules. The three bus controllers are connected by a DMA bus for faster transfer of data. The microprocessor controls the directions of the DMA transfers by data written to a control register.