Abstract: The unmanned flying vaccine administration system comprises a drone, a vaccine delivery system, an interaction system. The drone is a vaccine injection flying robot that avoids the dangers of in-person vaccination. The vaccine delivery system is an electronic system that harnesses the power of technology to vaccinate people safely and efficiently. The interaction system is an electronic system armed with an Artificial Intelligence infrastructure. The present invention gathers energy by solar power, administers vaccines with a vaccine injection arm, and properly stores vaccines at the desired temperature with a storage container. The computing device controls the main modules that are designed for vaccine delivery and administration. The interaction system has a patient interface camera, a patient interface display, and a temperature sensor that monitor the state of the patient after receiving a vaccination to ensure the health and safety of the patient.