Abstract: An apparatus arranged to heat aerosolizable material to volatilize at least one component of the aerosolizable material is described. The apparatus has a heating zone to receive at least a portion of an article that includes aerosolizable material. The apparatus also has a magnetic field generator including a helical inductor coil to generate a varying magnetic field. The helical inductor coil defines an inductor zone within the inductor coil. The apparatus also has an elongate heating element which is heatable by penetration with the varying magnetic field and arranged to heat the heating zone. The elongate heating element extends between the heating zone and the inductor zone.

Abstract: Novel methods and compositions are provided for inhibiting interactions between human immunodeficiency viruses (HIVs) and viral coreceptors, including CXCR4 and/or CCR5 coreceptors. The anti-coreceptor binding agent includes a novel peptide portion of the gp120 envelope protein of HIV-1, as well as peptide analogs and mimetics of this peptide, that specifically binds to, or modulates activity of, the coreceptors(s). The anti-coreceptor binding agent is useful as a prophylactic or therapeutic treatment to prevent or inhibit HIV binding to a susceptible cell and thereby reduces infection and/or moderates or treats related diseases. In alternative embodiments, the peptides, analogs and mimetics are effective to inhibit direct co-receptor binding by HIV virus, coreceptor binding by HIV gp120 proteins or peptides, HIV fusion with target host cells, HIV virion entry into host cells, HIV replication, and HIV transmission between cells and hosts.