Patents by Inventor Connor O'Rourke
Connor O'Rourke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12239650Abstract: The present invention relates to compounds with high chemical stability and methods for inhibiting the pathological activity of NETs in a subject. In particular, the invention relates to compounds with high chemical stability, uses thereof and methods for inhibiting or ameliorating NET mediated ailments (such as, for example, sepsis, systemic immune response syndrome (SIRS) and ischemia reperfusion injury (IRI)). More particularly, the invention relates to methods and uses of a polyanionic sulfated cellobioside modified with a small uncharged glycosidically linked substituent at its reducing terminus, wherein the presence of the substituent results in a molecule with high chemical stability without affecting the ability of the molecule to be effective in the therapy of NET mediated ailments. For example, the present invention relates to methods and uses of ?-O-methyl cellobioside sulfate (mCBS) or a pharmaceutically acceptable salt thereof (e.g., mCBS.Type: GrantFiled: February 25, 2019Date of Patent: March 4, 2025Assignees: The Australian National University, Griffith UniversityInventors: Christopher Parish, Connor O'Meara, Lucy Coupland, Benjamin Ju Chye Quah, Farzaneh Kordbacheh, Anna Orlov, Anna Browne, Ross Stephens, Gregory David Tredwell, Lee Andrew Philip, Karen Knox, Laurence Mark von Itzstein, Chih-Wei Chang, Anne Bruestle, David Anak Simon Davis
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Publication number: 20240358437Abstract: An anatomy visualization device may include a display, an optical sensor, and processing circuitry. The processing circuitry may be configured to capture, via the optical sensor, body registration points on a body of an individual, receive external anatomical measurements of the body, apply the external anatomical measurements to a body shape model, and determine an organ placement prediction for the body based on the application of external anatomical measurements to the body shape model. The organ placement prediction may include organ position information, organ size information, and organ shape information for a plurality of organs. The processing circuitry may also align the organ placement prediction with the body registration points and render, on the display, the organ placement prediction in alignment with the body registration points as an augmented reality object on the body.Type: ApplicationFiled: April 26, 2024Publication date: October 31, 2024Applicant: The Johns Hopkins UniversityInventors: Robert S. Armiger, Catherine M. Carneal, Nathan G. Drenkow, Nathanael P. Kuo, Connor O. Pyles, Anna E. Knight
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Patent number: 11963622Abstract: Child carrier which is configured to be releasably and removably secured to a backpack worn by another person. The child carrier may be lightweight and collapsible such that it is easily stored when not in use. The child carrier may be configured to be worn on a front of a person's body while the backpack is worn on the back.Type: GrantFiled: March 3, 2022Date of Patent: April 23, 2024Assignee: Trail Magik LLCInventors: Katie O'Mara, Connor O'Mara
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Publication number: 20230255992Abstract: The present invention relates to compounds with high chemical stability and methods for inhibiting the pathological activity of extracellular histones in a subject. In particular, the invention relates to compounds with high chemical stability, uses thereof and methods for inhibiting or ameliorating extracellular histone mediated ailments (such as, for example, sepsis, systemic immune response syndrome (SIRS) and ischemia reperfusion injury (IRO). More particularly, the invention relates to methods and uses of a polyanionic sulfated cellobioside modified with a small uncharged glycosidically linked substituent at its reducing terminus, wherein the presence of the substituent results in a molecule with high chemical stability without affecting the ability of the molecule to be effective in the therapy of extracellular histone mediated ailments. For example, the present invention relates to methods and uses of ?-O-methyl cellobioside sulfate (mCBS) or a pharmaceutically acceptable salt thereof (e.g.Type: ApplicationFiled: February 6, 2023Publication date: August 17, 2023Applicants: The Australian National University, Griffith UniversityInventors: Christopher Parish, Connor O'Meara, Lucy Coupland, Benjamin Ju Chye Quah, Farzaneh Kordbacheh, Anna Orlov, Anna Browne, Ross Stephens, Gregory David Tredwell, Lee Andrew Philip, Karen Knox, Laurence Mark von Itzstein, Chih-Wei Chang, Anne Brüstle, David Anak Simon Davis
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Patent number: 11679342Abstract: A separation device configured to separate light and heavy components of an effluent mixture. The separation device includes a separation tank, an inlet discharge, an outlet diffuser, and a baffle. The separation tank includes a tank reservoir for containing the effluent mixture during separation, with light components configured to migrate upwardly toward a static water line and heavy components configured to sink adjacent the bottom. The inlet discharge is located within the tank reservoir to supply effluent mixture to the separation tank. The outlet diffuser is spaced from the inlet discharge and located within the tank reservoir to receive a heavy component of the effluent mixture after separation. The baffle is located within the tank reservoir to separate the inlet discharge from the outlet diffuser. The baffle presents a baffle opening adjacent the static water line.Type: GrantFiled: October 12, 2021Date of Patent: June 20, 2023Assignee: Schier Products CompanyInventors: Tad Asay, Connor O'Boyle, Benjamin F. Brown, Grahm Heide
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Patent number: 11680669Abstract: A conduit assembly for a separation device is described herein. The conduit assembly includes a first conduit segment, a second conduit segment, and a removable flow control insert or cartridge, which may be easily installed and uninstalled without removing other components of the conduit assembly from the separation device. The flow control insert may be installed within a top opening of the second conduit segment and includes a projection that extends into the conduit assembly and obstructs or restricts fluid flow at the juncture between the first and second conduit segments.Type: GrantFiled: January 29, 2021Date of Patent: June 20, 2023Assignee: Schier Products CompanyInventors: Benjamin F. Brown, Todd E. Uhlenhake, Luke J. Ismert, Charles M. Ismert, Connor O'Boyle, Grahm Heide
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Patent number: 11628179Abstract: The present invention relates to compounds with high chemical stability and methods for inhibiting the pathological activity of extracellular histones in a subject. In particular, the invention relates to compounds with high chemical stability, uses thereof and methods for inhibiting or ameliorating extracellular histone mediated ailments (such as, for example, sepsis, systemic immune response syndrome (SIRS) and ischemia reperfusion injury (IRI)). More particularly, the invention relates to methods and uses of a polyanionic sulfated cellobioside modified with a small uncharged glycosidically linked substituent at its reducing terminus, wherein the presence of the substituent results in a molecule with high chemical stability without affecting the ability of the molecule to be effective in the therapy of extracellular histone mediated ailments. For example, the present invention relates to methods and uses of ?-O-methyl cellobioside sulfate (mCBS) or a pharmaceutically acceptable salt thereof (e.g., mCBS.Type: GrantFiled: December 14, 2018Date of Patent: April 18, 2023Assignees: The Australian National University, Griffith UniversityInventors: Christopher Parish, Connor O'Meara, Lucy Coupland, Benjamin Ju Chye Quah, Farzaneh Kordbacheh, Anna Orlov, Anna Browne, Ross Stephens, Gregory David Tredwell, Lee Andrew Philip, Karen Knox, Laurence Mark von Itzstein, Chih-Wei Chang, Anne Brüstle, David Anak Simon Davis
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Publication number: 20220279937Abstract: Child carrier which is configured to be releasably and removably secured to a backpack worn by another person. The child carrier may be lightweight and collapsible such that it is easily stored when not in use. The child carrier may be configured to be worn on a front of a person's body while the backpack is worn on the back.Type: ApplicationFiled: March 3, 2022Publication date: September 8, 2022Inventors: KATIE O'MARA, CONNOR O'MARA
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Publication number: 20220169673Abstract: A group of specific sulfated flavonoid agents carrying cholesterol modification display promising in vivo anti-cancer activity through selective inhibition of cancer stem cells, and not of adult or hematopoietic stem cells. The compounds exhibit high potency, excellent oral bioavailability and a physiologically relevant therapeutic window.Type: ApplicationFiled: March 6, 2020Publication date: June 2, 2022Inventors: Umesh R. DESAI, Balaji NAGARAJAN, Connor O'HARA, Daniel Kwame AFOSAH, Elsamani I. ABDELFADIEL, Jyothi SISTLA, Rahaman Navaz GANGJI, Ravikumar ONGOLU, Shravan MORLA, Viji SANKARANARAYANAN, Bhaumik B. PATEL, Chetna SHARON, Rio BOOTHELLO, Alberto VERA
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Publication number: 20220168327Abstract: The present invention relates to compounds with high chemical stability and methods for inhibiting the pathological activity of NETs in a subject. In particular, the invention relates to compounds with high chemical stability, uses thereof and methods for inhibiting or ameliorating NET mediated ailments (such as, for example, sepsis, systemic immune response syndrome (SIRS) and ischemia reperfusion injury (IRI)). More particularly, the invention relates to methods and uses of a polyanionic sulfated cellobioside modified with a small uncharged glycosidically linked substituent at its reducing terminus, wherein the presence of the substituent results in a molecule with high chemical stability without affecting the ability of the molecule to be effective in the therapy of NET mediated ailments. For example, the present invention relates to methods and uses of ?-O-methyl cellobioside sulfate (mCBS) or a pharmaceutically acceptable salt thereof (e.g., mCBS.Type: ApplicationFiled: February 25, 2019Publication date: June 2, 2022Inventors: Christopher Parish, Connor O'Meara, Lucy Coupland, Benjamin Ju Chye Quah, Farzaneh Kordbacheh, Anna Bezos, Anna Browne, Ross Stephens, Gregory David Tredwell, Lee Andrew Philip, Karen Knox, Laurence Mark von Itzstein, Chih-Wei Chang, Anne Brüstle, David Anak Simon Davis
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Publication number: 20220111311Abstract: A separation device configured to separate light and heavy components of an effluent mixture. The separation device includes a separation tank, an inlet discharge, an outlet diffuser, and a baffle. The separation tank includes a tank reservoir for containing the effluent mixture during separation, with light components configured to migrate upwardly toward a static water line and heavy components configured to sink adjacent the bottom. The inlet discharge is located within the tank reservoir to supply effluent mixture to the separation tank. The outlet diffuser is spaced from the inlet discharge and located within the tank reservoir to receive a heavy component of the effluent mixture after separation. The baffle is located within the tank reservoir to separate the inlet discharge from the outlet diffuser. The baffle presents a baffle opening adjacent the static water line.Type: ApplicationFiled: October 12, 2021Publication date: April 14, 2022Inventors: Tad Asay, Connor O'Boyle, Benjamin F. Brown, Grahm Heide
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Publication number: 20210239247Abstract: A conduit assembly for a separation device is described herein. The conduit assembly includes a first conduit segment, a second conduit segment, and a removable flow control insert or cartridge, which may be easily installed and uninstalled without removing other components of the conduit assembly from the separation device. The flow control insert may be installed within a top opening of the second conduit segment and includes a projection that extends into the conduit assembly and obstructs or restricts fluid flow at the juncture between the first and second conduit segments.Type: ApplicationFiled: January 29, 2021Publication date: August 5, 2021Inventors: Benjamin F. Brown, Todd E. Uhlenhake, Luke J. Ismert, Charles M. Ismert, Connor O'Boyle, Grahm Heide
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Publication number: 20210205343Abstract: The present invention relates to compounds with high chemical stability and methods for inhibiting the pathological activity of extracellular histones in a subject. In particular, the invention relates to compounds with high chemical stability, uses thereof and methods for inhibiting or ameliorating extracellular histone mediated ailments (such as, for example, sepsis, systemic immune response syndrome (SIRS) and ischemia reperfusion injury (IRI)). More particularly, the invention relates to methods and uses of a polyanionic sulfated cellobioside modified with a small uncharged glycosidically linked substituent at its reducing terminus, wherein the presence of the substituent results in a molecule with high chemical stability without affecting the ability of the molecule to be effective in the therapy of extracellular histone mediated ailments. For example, the present invention relates to methods and uses of ?-O-methyl cellobioside sulfate (mCBS) or a pharmaceutically acceptable salt thereof (e.g., mCBS.Type: ApplicationFiled: December 14, 2018Publication date: July 8, 2021Inventors: Christopher Parish, Connor O'Meara, Lucy Coupland, Benjamin Ju Chye Quah, Farzaneh Kordbacheh, Anna Bezos, Anna Browne, Ross Stephens, Gregory David Tredwell, Lee Andrew Philip, Karen Knox, Laurence Mark von Itzstein, Chih-Wei Chang, Anne Brüstle, David Anak Simon Davis
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Publication number: 20160143646Abstract: Occlusive plugs are provided which comprise a single elongate member that is insertable into and through a microcatheter and assumes a space-occupying shape when deployed into a vascular structure. The elongate member optionally includes one or more polymer fibers, one or more polymer sleeves to secure the polymer fibers to the elongate member, and/or a radiopaque marker band.Type: ApplicationFiled: November 24, 2015Publication date: May 26, 2016Applicant: Boston Scientific Scimed, Inc.Inventors: Frank Ryan, Connor O'Sullivan, John Allan O'Brien
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Patent number: 9240902Abstract: An attachment server network including at least two attachment servers in communication with one another, each of the attachment servers for converting email attachments in response to view requests received from portable electronic devices, each of the attachment servers having a respective cache for storing data corresponding to previously converted attachments, the data being available to any of the attachment servers in the attachment server network.Type: GrantFiled: November 29, 2011Date of Patent: January 19, 2016Assignee: BLACKBERRY LIMITEDInventors: Daryl Martin, Ahmed E. Hassan, Connor O'Rourke
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Patent number: 8014766Abstract: A method for providing wavetable information to a wireless device from a content server over a wireless network, the wavetable information including a plurality of samples corresponding to a plurality of notes, comprising: in response to a request from the wireless device, receiving at a proxy server the wavetable information from the content server; filtering the wavetable information in accordance with a selection of samples contained in the request; and, transmitting the filtered wavetable information to the wireless device.Type: GrantFiled: December 20, 2010Date of Patent: September 6, 2011Assignee: Research in Motion LimitedInventor: Connor O'Rourke
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Publication number: 20110083545Abstract: A method for providing wavetable information to a wireless device from a content server over a wireless network, the wavetable information including a plurality of samples corresponding to a plurality of notes, comprising: in response to a request from the wireless device, receiving at a proxy server the wavetable information from the content server; filtering the wavetable information in accordance with a selection of samples contained in the request; and, transmitting the filtered wavetable information to the wireless device.Type: ApplicationFiled: December 20, 2010Publication date: April 14, 2011Applicant: RESEARCH IN MOTION LIMITEDInventor: Connor O'ROURKE
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Patent number: 7881707Abstract: A method for providing wavetable information to a wireless device from a content server over a wireless network, the wavetable information including a plurality of samples corresponding to a plurality of notes, comprising: in response to a request from the wireless device, receiving at a proxy server the wavetable information from the content server; filtering the wavetable information in accordance with a selection of samples contained in the request; and, transmitting the filtered wavetable information to the wireless device.Type: GrantFiled: April 24, 2009Date of Patent: February 1, 2011Assignee: Research In Motion LimitedInventor: Connor O'Rourke
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Publication number: 20090328028Abstract: In one aspect, an electronic document for updating resource files for an application comprises logical names used by the application for referring to resource files and parameters for specifying constraints for the resource files. In another aspect, the electronic document comprises an application identifier identifying an application to which the electronic document corresponds, and a universal resource identifier identifying a resource file for use with the application.Type: ApplicationFiled: June 25, 2008Publication date: December 31, 2009Inventors: Connor O'Rourke, Tony Salomone
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Publication number: 20090227200Abstract: A method for providing wavetable information to a wireless device from a content server over a wireless network, the wavetable information including a plurality of samples corresponding to a plurality of notes, comprising: in response to a request from the wireless device, receiving at a proxy server the wavetable information from the content server; filtering the wavetable information in accordance with a selection of samples contained in the request; and, transmitting the filtered wavetable information to the wireless device.Type: ApplicationFiled: April 24, 2009Publication date: September 10, 2009Applicant: RESEARCH IN MOTION LIMITEDInventor: Connor O'Rourke