Patents by Inventor Connor Tsuchida

Connor Tsuchida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF CRISPR-CAS EFFECTOR POLYPEPTIDES AND TRANSGENES
    Publication number: 20220403379
    Abstract: The present disclosure provides virus-like particles (VLPs) comprising: i) a CRISPR-Cas effector polypeptide; ii) a recombinant lentivirus comprising a nucleotide sequence encoding a therapeutic polypeptide having a length of from about 250 amino acids to about 3,000 amino acids, where the VLP comprises a pseudotyping viral glycoprotein and/or a polypeptide that provides for binding to a target cell. The present disclosure provides systems for producing a VLP. The present disclosure provides methods of delivering a therapeutic protein, using a VLP of the present disclosure.
    Type: Application
    Filed: May 25, 2022
    Publication date: December 22, 2022
    Inventors: Jennifer A. Doudna, Jennifer Hamilton, Connor Tsuchida