Patents by Inventor Conor Evans
Conor Evans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250160701Abstract: Systems and methods of optical transcutaneous oxygenation monitoring. The oxygenation monitor comprises a photoluminescent oxygen-sensitive probe, a photon source positioned to direct photons at the probe, a photodetector positioned to detect light emitted from the probe when the photon source directs photons at the probe, a controller in electrical communication with the photon source and the photodetector, the controller being configured to execute a program stored in the controller to calculate a level of oxygen adjacent the probe from an electrical signal received from the photodetector. The photon source, the photodetector, and the controller are disposed in or on a support structure.Type: ApplicationFiled: January 17, 2025Publication date: May 22, 2025Applicant: The General Hospital CorporationInventors: Conor Evans, Nicholas Nowell, Emmanouil Rousakis
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Patent number: 12232870Abstract: Systems and methods of optical transcutaneous oxygenation monitoring. The oxygenation monitor comprises a photoluminescent oxygen-sensitive probe, a photon source positioned to direct photons at the probe, a photodetector positioned to detect light emitted from the probe when the photon source directs photons at the probe, a controller in electrical communication with the photon source and the photodetector, the controller being configured to execute a program stored in the controller to calculate a level of oxygen adjacent the probe from an electrical signal received from the photodetector. The photon source, the photodetector, and the controller are disposed in or on a support structure.Type: GrantFiled: August 5, 2022Date of Patent: February 25, 2025Assignee: The General Hospital CorporationInventors: Conor Evans, Nicholas Nowell, Emmanouil Rousakis
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Publication number: 20240088402Abstract: A solid oxide cell (SOC) includes a fuel electrode, an oxygen electrode, and an electrolyte. In some embodiments, the solid oxide cell is a reversible proton conducting solid oxide cell (P-rSOC). In some embodiments, the oxygen electrode is a perovskite oxide material having a formula such as PrBa0.8Ca0.2Co2O5+?, PrBa0.9Co1.96Nb0.04O5, PrBaCo1.6Fc0.2Nb0.2?xO5+?, PrBa0.5Sr0.5Co1.5Fe0.5O5+? (PBSCF), or PrBaCo2O5+? (PBC) and it is coated with a perovskite oxide catalyst such as PrCoO3.Type: ApplicationFiled: June 30, 2023Publication date: March 14, 2024Inventors: Conor Evans, Meilin Liu, Ying Liu, Yucun Zhou
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Publication number: 20230113642Abstract: Systems and methods of optical transcutaneous oxygenation monitoring. The oxygenation monitor comprises a photoluminescent oxygen-sensitive probe, a photon source positioned to direct photons at the probe, a photodetector positioned to detect light emitted from the probe when the photon source directs photons at the probe, a controller in electrical communication with the photon source and the photodetector, the controller being configured to execute a program stored in the controller to calculate a level of oxygen adjacent the probe from an electrical signal received from the photodetector. The photon source, the photodetector, and the controller are disposed in or on a support structure.Type: ApplicationFiled: August 5, 2022Publication date: April 13, 2023Inventors: Conor Evans, Nicholas Nowell, Emmanouil Rousakis
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Patent number: 11406297Abstract: Systems and methods of optical transcutaneous oxygenation monitoring. The oxygenation monitor comprises a photoluminescent oxygen-sensitive probe, a photon source positioned to direct photons at the probe, a photodetector positioned to detect light emitted from the probe when the photon source directs photons at the probe, a controller in electrical communication with the photon source and the photodetector, the controller being configured to execute a program stored in the controller to calculate a level of oxygen adjacent the probe from an electrical signal received from the photodetector. The photon source, the photodetector, and the controller are disposed in or on a support structure.Type: GrantFiled: May 15, 2017Date of Patent: August 9, 2022Assignee: The General Hospital CorporationInventors: Conor Evans, Nicholas Nowell, Emmanouil Rousakis
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Publication number: 20190150811Abstract: Systems and methods of optical transcutaneous oxygenation monitoring. The oxygenation monitor comprises a photoluminescent oxygen-sensitive probe, a photon source positioned to direct photons at the probe, a photodetector positioned to detect light emitted from the probe when the photon source directs photons at the probe, a controller in electrical communication with the photon source and the photodetector, the controller being configured to execute a program stored in the controller to calculate a level of oxygen adjacent the probe from an electrical signal received from the photodetector. The photon source, the photodetector, and the controller are disposed in or on a support structure.Type: ApplicationFiled: May 15, 2017Publication date: May 23, 2019Inventors: Conor Evans, Nicholas Nowell, Emmanouil Rousakis
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Patent number: 7542137Abstract: The invention provides a system and method for automatic real-time monitoring for the presence of a pathogen in water using coherent anti-stokes Raman scattering (CARS) microscopy. Water sample trapped in a trapping medium is provided to a CARS imager. CARS images are provided to a processor for automatic analyzing for the presence of image artifacts having pre-determined features characteristic to the pathogen. If a match is found, a CARS spectrum is taken and compared to a stored library of reference pathogen-specific spectra for pathogen identification. The system enables automatic pathogen detection in flowing water in real time.Type: GrantFiled: July 23, 2007Date of Patent: June 2, 2009Assignees: University of Ottawa, President and Fellows of Harvard CollegeInventors: Sangeeta Murugkar, Hanan Anis, Xiaoliang Sunney Xie, Conor Evans
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Patent number: 7414729Abstract: A system is disclosed for detecting a signal field from a sample volume. The system includes a source system and an optical fiber system. The source system provides a first electromagnetic field at a first frequency and a second electromagnetic field at a second frequency that is different from the first frequency. The optical fiber system includes at least one optical fiber for guiding the first and second electromagnetic fields to the sample volume to generate coherent radiation characteristic of molecular vibrations by non-linear interaction of the first and second fields with the sample volume. The optical fiber system also receives the signal field resulting from the coherent radiation, and guides the signal field to a detector.Type: GrantFiled: April 12, 2006Date of Patent: August 19, 2008Assignee: President and Fellows of Harvard CollegeInventors: Xiaoliang Sunney Xie, Francois Légaré, Feruz Ganikhanov, Conor Evans
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Patent number: 7388668Abstract: A system is disclosed for detecting a non-linear coherent field induced in a sample volume. The system includes a first source for generating a first electromagnetic field at a first frequency, a second source for generating a second electromagnetic field at a second frequency, first optics for directing the first and second electromagnetic fields toward the sample volume, second optics for directing the first and second electromagnetic fields toward a local oscillator volume, and an interferometer. The interferometer is for interfering a first scattering field that is generated by the interaction of the first and second electromagnetic fields in the sample volume, with a second scattering field that is generated by the interaction of the first and second electromagnetic fields in the local oscillator volume.Type: GrantFiled: June 3, 2005Date of Patent: June 17, 2008Assignee: President & Fellows of Harvard CollegeInventors: Eric O. Potma, Conor Evans, Xiaoliang Sunney Xie
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Patent number: 7352458Abstract: A system is disclosed for detecting a nonlinear coherent field induced in a sample. The system includes optics, a modulation system, and a detector system. The optics are for directing a first electromagnetic field at a first frequency ?1 and a second electromagnetic field at a second frequency ?2 toward a focal volume such that a difference frequency ?1–?2 is resonant with a vibrational frequency of a sample in the focal volume. The modulation system is for modulating the difference frequency ?1–?2 such that the difference frequency ?1–?2 is tuned in and out of the vibrational frequency of the sample of at a modulation frequency. The detector system is for detecting an optical field that is generated through non-linear interaction of ?1 and ?2 and the sample responsive to the modulation frequency.Type: GrantFiled: March 15, 2006Date of Patent: April 1, 2008Assignee: President and Fellows of Harvard CollegeInventors: Xiaoliang Sunney Xie, Feruz Ganikhanov, Conor Evans
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Publication number: 20080059135Abstract: The invention provides a system and method for automatic real-time monitoring for the presence of a pathogen in water using coherent anti-stokes Raman scattering (CARS) microscopy. Water sample trapped in a trapping medium is provided to a CARS imager. CARS images are provided to a processor for automatic analyzing for the presence of image artifacts having pre-determined features characteristic to the pathogen. If a match is found, a CARS spectrum is taken and compared to a stored library of reference pathogen-specific spectra for pathogen identification. The system enables automatic pathogen detection in flowing water in real time.Type: ApplicationFiled: July 23, 2007Publication date: March 6, 2008Inventors: Sangeeta Murugkar, Hanan Anis, Xiaoliang Xie, Conor Evans
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Publication number: 20070091305Abstract: A system is disclosed for detecting a nonlinear coherent field induced in a sample. The system includes optics, a modulation system, and a detector system. The optics are for directing a first electromagnetic field at a first frequency ?1 and a second electromagnetic field at a second frequency ?2 toward a focal volume such that a difference frequency ?1??2 is resonant with a vibrational frequency of a sample in the focal volume. The modulation system is for modulating the difference frequency ?1??2 such that the difference frequency ?1??2 is tuned in and out of the vibrational frequency of the sample at a modulation frequency. The detector system is for detecting an optical field that is generated through non-linear interaction of ?1 and ?2 and the sample responsive to the modulation frequency.Type: ApplicationFiled: March 15, 2006Publication date: April 26, 2007Inventors: Xiaoliang Xie, Feruz Ganikhanov, Conor Evans
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Publication number: 20070088219Abstract: A system is disclosed for detecting a signal field from a sample volume. The system includes a source system and an optical fiber system. The source system provides a first electromagnetic field at a first frequency and a second electromagnetic field at a second frequency that is different from the first frequency. The optical fiber system includes at least one optical fiber for guiding the first and second electromagnetic fields to the sample volume to generate coherent radiation characteristic of molecular vibrations by non-linear interaction of the first and second fields with the sample volume. The optical fiber system also receives the signal field resulting from the coherent radiation, and guides the signal field to a detector.Type: ApplicationFiled: April 12, 2006Publication date: April 19, 2007Inventors: Xiaoliang Xie, Francois Legare, Feruz Ganikhanov, Conor Evans
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Publication number: 20050280827Abstract: A system is disclosed for detecting a non-linear coherent field induced in a sample volume. The system includes a first source for generating a first electromagnetic field at a first frequency, a second source for generating a second electromagnetic field at a second frequency, first optics for directing the first and second electromagnetic fields toward the sample volume, second optics for directing the first and second electromagnetic fields toward a local oscillator volume, and an interferometer. The interferometer is for interfering a first scattering field that is generated by the interaction of the first and second electromagnetic fields in the sample volume, with a second scattering field that is generated by the interaction of the first and second electromagnetic fields in the local oscillator volume.Type: ApplicationFiled: June 3, 2005Publication date: December 22, 2005Inventors: Eric Potma, Conor Evans, Xiaoliang Xie