Abstract: An intelligent laminate dressing system (1) for monitoring and treating a wound made up an absorbent pad (2), a sensor (16) for detecting wound data and an electronic module (17) communicable with the sensor (16), the sensor (16) and the electronic module (17) being positionally offset with respect to the centre of the absorbent pad (2).

Abstract: The invention provides a dressing system for a wound comprising an absorbent pad; at least one sensor for detecting wound or dressing data, wherein the at least one sensor is a moisture sensor; a flexible electronic circuit communicable with the sensor; a backing film adapted to cooperate with the absorbent pad, wherein the electronic circuit and the at least one sensor is printed directly on the backing film; and a communications module adapted to communicate the wound data from the electronic circuit to a user or clinician. The invention provides a simple to use disposable dressing wound system that is effective in providing dressing wound data that provides an indicator of the status of the wound as well as information that the dressing wound system needs to be replaced.

Abstract: The present invention relates to a method for fabricating a microneedle which comprises the steps of spraying a composition into a mould, drying the composition and removal of the dried composition from the mould, thereby forming a microneedle that, when applied to the skin of a subject, pierces the stratum corneum to access the underlying tissue of the subject. The present invention also relates to a method for coating a microneedle which comprises the steps of spraying a composition onto a microneedle and drying the composition at an ambient temperature, thereby forming a coated microneedle that, when applied to the skin of a subject, pierces the stratum corneum to deliver the sprayed material to the underlying tissue of the subject.

Abstract: The present invention provides vaccination methods using microneedle arrays which, when applied to the skin of a subject, create a defined total pore volume. Arrays may be chosen of varying total microneedle volumes (small, intermediate or large) for use in immunisation regimes to induce different T-cell and antibody responses in the subject. The present invention also provides kits for use in such vaccination method(s) comprising the appropriate microneedle array(s).

Abstract: A silicon wafer is used as a substrate (1). A thin layer of metal is deposited and etched to form device metallisation (3), including electrodes and bondpads. A passivation layer (4) of silicon nitride is patterned to open access points to the metal. A lower sacrificial layer (5) is formed from polyimide and is patterned (at 5(a) and 5(b)) to open anchor regions for a device and for bridges that will define lateral etch channels for package evacuation. Structural materials that form a MEMS device (6) and bridges (13) are then deposited and patterned. The bridges (13) are patterned simultaneously with the device 6 on the lower sacrificial layer (5). An upper sacrificial layer (7) is then deposited over the device (6) and the lower sacrificial layer (5) and is patterned to open anchor regions (8) for an encapsulation layer (10). Both sacrificial layers are then simultaneously removed in an oxygen plasma ash through lateral etc channels (15).