Patents by Inventor Conrad Florian Bentzinger

Conrad Florian Bentzinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vitro production of muscle stem cells
    Patent number: 11413316
    Abstract: An in vitro method of producing a population of muscle stem cells comprising co-culturing pluripotent stem cells, embryonic fibroblast cells and endothelial cells in 3D cell culture.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: August 16, 2022
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Omid Mashinchian, Jerome Feige, Conrad Florian Bentzinger
  • IN VITRO PRODUCTION OF MUSCLE STEM CELLS
    Publication number: 20190365821
    Abstract: An in vitro method of producing a population of muscle stem cells comprising co-culturing pluripotent stem cells, embryonic fibroblast cells and endothelial cells in 3D cell culture.
    Type: Application
    Filed: November 3, 2017
    Publication date: December 5, 2019
    Inventors: Omid Mashinchian, Jerome Feige, Conrad Florian Bentzinger
  • WNT7A compositions and method of using the same
    Patent number: 9732130
    Abstract: There are provided compositions and methods for modulating stem cell division, in particular, division symmetry. It has been demonstrated that Wnt7a polypeptide fragments promoting symmetrical expansion of stem cells. The compositions and methods of the invention are useful, for example, in modulating stem cell division symmetry in vitro, ex vivo, and in vivo, in replenishing and expanding the stem cell pool, and in promoting the formation, maintenance, repair and regeneration of tissue.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: August 15, 2017
    Assignee: Ottawa Hospital Research Institute
    Inventors: Michael A. Rudnicki, Conrad Florian Bentzinger, Radoslav Zinoviev
  • WNT INDUCED MOTILITY AND ENHANCED ENGRAFTMENT OF CELLS
    Publication number: 20170087188
    Abstract: The invention provides cell therapy compositions and associated methods. In particular embodiments, improved therapeutic cells and improved cell-based gene therapies for promoting cell or tissue formation, regeneration, repair or maintenance in a subject in need thereof are provided.
    Type: Application
    Filed: March 27, 2015
    Publication date: March 30, 2017
    Inventors: Michael A. RUDNICKI, Conrad Florian BENTZINGER
  • WNT7A COMPOSITIONS AND METHOD OF USING THE SAME
    Publication number: 20150111822
    Abstract: There are provided compositions and methods for modulating stem cell division, in particular, division symmetry. It has been demonstrated that Wnt7a polypeptide fragments promoting symmetrical expansion of stem cells. The compositions and methods of the invention are useful, for example, in modulating stem cell division symmetry in vitro, ex vivo, and in vivo, in replenishing and expanding the stem cell pool, and in promoting the formation, maintenance, repair and regeneration of tissue.
    Type: Application
    Filed: September 14, 2012
    Publication date: April 23, 2015
    Inventors: Michael A. Rudnicki, Conrad Florian Bentzinger, Radoslav Zinoviev