Patents by Inventor Conrad Russell CRUZ

Conrad Russell CRUZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Generating HPV antigen-specific cells from a naive T cell population
    Patent number: 11999967
    Abstract: Safe, rapid and efficient methods for producing antigen-specific T cells recognizing human papilloma virus or HPV antigens.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: June 4, 2024
    Assignee: CHILDREN'S NATIONAL MEDICAL CENTER
    Inventors: Catherine M. Bollard, Conrad Russell Cruz, Patrick J. Hanley, Michael Keller
  • NANOPARTICLE-MEDIATED IMMUNE CELL MANUFACTURE AND USE THEREOF
    Publication number: 20240026294
    Abstract: The present disclosure generally relates target cancer cell specific immunotherapy compositions, methods of making and use thereof. Also provided in the disclosure are methods of treating a cancer in a subject in need thereof.
    Type: Application
    Filed: July 10, 2023
    Publication date: January 25, 2024
    Inventors: ELIZABETH SWEENEY, ROHAN FERNANDES, MATTHEW TOVAR, PALAK SEKHRI, PREETHI BALA BALAKRISHNAN, CONRAD RUSSELL CRUZ
  • Generating HPV antigen-specific cells from a naive T cell population
    Patent number: 11649437
    Abstract: Safe, rapid and efficient methods for producing antigen-specific T cells recognizing human papilloma virus or HPV antigens.
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: May 16, 2023
    Assignee: CHILDREN'S NATIONAL MEDICAL CENTER
    Inventors: Catherine M. Bollard, Conrad Russell Cruz, Patrick J. Hanley, Michael Keller
  • GENERATING HPV ANTIGEN-SPECIFIC CELLS FROM A NAIVE T CELL POPULATION
    Publication number: 20210163892
    Abstract: Safe, rapid and efficient methods for producing antigen-specific T cells recognizing human papilloma virus or HPV antigens.
    Type: Application
    Filed: January 19, 2021
    Publication date: June 3, 2021
    Applicant: CHILDREN'S NATIONAL MEDICAL CENTER
    Inventors: Catherine M. BOLLARD, Conrad Russell CRUZ, Patrick J. HANLEY
  • GENERATING HPV ANTIGEN-SPECIFIC CELLS FROM A NAIVE T CELL POPULATION
    Publication number: 20210155900
    Abstract: Safe, rapid and efficient methods for producing antigen-specific T cells recognizing human papilloma virus or HPV antigens.
    Type: Application
    Filed: February 5, 2021
    Publication date: May 27, 2021
    Applicant: CHILDREN'S NATIONAL MEDICAL CENTER
    Inventors: Catherine M. BOLLARD, Conrad Russell CRUZ, Patrick J. HANLEY
  • Generating HPV antigen-specific cells from a naive T cell population
    Patent number: 10934525
    Abstract: Safe, rapid and efficient methods for producing antigen-specific T cells recognizing human papilloma virus or HPV antigens.
    Type: Grant
    Filed: October 31, 2016
    Date of Patent: March 2, 2021
    Assignee: Children's National Medical Center
    Inventors: Catherine M. Bollard, Conrad Russell Cruz, Patrick J. Hanley
  • FIXED RATIO EX VIVO ACTIVATED MIXED LYMPHOCYTE PRODUCTS FOR USE IN THE TREATMENT OF CANCER
    Publication number: 20210046119
    Abstract: The present invention provides isolated cell compositions for the treatment of cancer, including hematological and solid tumors, comprising a selected, fixed ratio of multiple ex vivo activated lymphocytic cell subsets, including specific immune effector cells directed to specific tumor associated antigens (TAAs), viral associated tumor antigens (VATA), glycolipids, or a combination thereof. By selecting specific fixed ratios of different lymphocytic cell subsets, an immune response which is comprehensive and broad pin biological and immune effector function is provided, enhancing the ability of the administered cells to mount an effective and robust immune response.
    Type: Application
    Filed: April 22, 2019
    Publication date: February 18, 2021
    Inventors: Catherine Bollard, Conrad Russell Cruz, Patrick Hanley
  • GENERATING HPV ANTIGEN-SPECIFIC CELLS FROM A NAIVE T CELL POPULATION
    Publication number: 20180312807
    Abstract: Safe, rapid and efficient methods for producing antigen-specific T cells recognizing human papilloma virus or HPV antigens.
    Type: Application
    Filed: October 31, 2016
    Publication date: November 1, 2018
    Applicant: Children's National Medical Center
    Inventors: Catherine M. BOLLARD, Conrad Russell CRUZ, Patrick J. HANLEY