Patents by Inventor Constance Brinckerhoff

Constance Brinckerhoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Inhibiting the Synthesis or Expression of Mmp-1
    Publication number: 20070237757
    Abstract: The present invention relates to the specific inhibition of matrix metalloproteinase 1 (MMP-1) using agents which inhibit the synthesis or expression of MMP-1. Such agents are useful for suppressing invasion or metastasis of a tumor cell and in the treatment, prevention and management of cancer.
    Type: Application
    Filed: June 10, 2005
    Publication date: October 11, 2007
    Inventors: Colby Wyatt, Constance Brinckerhoff
  • Methods of diagnosing, prognosticating and treating matrix metalloproteinase-1 related diseases via a matrix metalloproteinase-1 single nucleotide polymorphism
    Publication number: 20060183152
    Abstract: Methods and kits for diagnosing and prognosticating matrix metalloproteinase-1 related disease by detecting a single nucleotide polymorphism in the promoter of the gene are provided. Also provided are methods of identifying agents which inhibit binding of transcriptions factors to the Ets transcription factor binding site created by or resulting from this single nucleotide polymorphism and methods of using these agents to treat matrix metalloproteinase-1 related diseases.
    Type: Application
    Filed: April 20, 2006
    Publication date: August 17, 2006
    Inventors: Constance Brinckerhoff, Joni Rutter