Patents by Inventor Constance Elizabeth Medlen

Constance Elizabeth Medlen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8445452
    Abstract: This invention relates to a fulvic acid and antibiotic combination for use in the treatment of various diseases and conditions. The invention further relates to the use of the combination for the treatment of various diseases and conditions, including bacterial infection. In particular, the bacteria are antibiotic resistant bacteria.
    Type: Grant
    Filed: June 4, 2009
    Date of Patent: May 21, 2013
    Assignee: Pfeinsmith Ltd.
    Inventors: Antonio Celestino Fernandes, Constance Elizabeth Medlen, Stephen Leivers
  • Publication number: 20040092584
    Abstract: A substance for use in the treatment of cancer, includes a compound selected from metallocenyl &bgr;-diketones Mc-CO—CZ1Z2-CO—R. Mc is Fc (ferrocenyl), Rc (ruthenocenyl) or Oc (osmocenyl), R is 11, alkyl or aryl and Z1 and Z2 are H, alkyl, aryl or substituted alkyl, ferrocenyl, the enol forms of the &bgr;-diketones and metal complexes of the &bgr;-diketones of the general formula M(&bgr;-diketonato)A1, M(&bgr;-diketonato)A1A2, M(&bgr;-diketonato)A1B1B2, M(&bgr;-diketonato)B1B2 and M(&bgr;-diketonato)B1B2B3B4. M is Rh or Ir, A1 and A2 are cyclic dienes having 6-8 carbons, or linear alkenes having 2-7 carbons. B1, B2, B3 and B4 are selected from CO, P(R1R2R3), P(OR1)(OR2)(OR3), R4 and X in which R1, R2, R3 and R4 are independently alkyl, phenyl or ferrocenyl, and X is a halide or a pseudohalide.
    Type: Application
    Filed: November 12, 2003
    Publication date: May 13, 2004
    Inventors: Johannes Christiaan Swarts, Constance Elizabeth Medlen
  • Patent number: 6630179
    Abstract: A pharmaceutical composition comprising an oxihumic acid, salt, ester, or derivative thereof as an active ingredient is disclosed. The composition is preferably administered only for stimulating lymphocytes in a human, animal, or bird. It may be used in treating viral and bacterial infections, HIV infections, opportunistic diseases, inflammation, pain and fever, cancer growth, and diseases associated with viral infection and a depressed immune system.
    Type: Grant
    Filed: June 20, 2001
    Date of Patent: October 7, 2003
    Assignee: Enerkom (Proprietary) Limited
    Inventors: Johannes Dekker, Constance Elizabeth Medlen
  • Patent number: 6569900
    Abstract: Fulvic acid salts, esters or derivatives thereof in pharmaceutical preparations are effective for treating inflammation, acne, exzema or bacterial or fungal or viral infections. These pharmaceutical preparations may be given either orally or topically in the form of a solution, paste, ointment, powder to humans or animals.
    Type: Grant
    Filed: July 9, 2001
    Date of Patent: May 27, 2003
    Assignee: Enerkom (Proprietary) Limited
    Inventors: Johannes Dekker, Constance Elizabeth Medlen
  • Patent number: 5763442
    Abstract: The invention provides the use of a riminophenazine in the manufacture of a medicament to treat parasitic infections. The riminophenazine may be used for the prophylactic treatments of maleria or for the therapeutic treatment of maleria. A known anti-maleria drug, e.g. chloroquine or mefloquine may be administered as well. The riminophenazine may be a compound of the general formula: ##STR1## wherein: R.sup.1 is selected from hydrogen atoms, halogen atoms, alkyl, alkoxy and trifluoromethyl radicals,R.sub.2 is selected from hydrogen or halogen atoms,R.sup.3 is selected from hydrogen atoms, alkyl, substituted alkyl, cycloalkyl, cycloalkylalkyl, unsubstituted heterocyclic radicals, substituted heterocyclic radicals, unsubstituted heterocyclicalkyl and substituted heterocyclicalkyl radicals.
    Type: Grant
    Filed: January 25, 1996
    Date of Patent: June 9, 1998
    Assignee: Universiteit Van Pretoria
    Inventors: Constance Elizabeth Medlen, Ronald Anderson
  • Patent number: 5763443
    Abstract: The invention concerns the new use of riminophenazines in the treatment of a patient who has built up, or could build up, resistance to a therapeutically active substance, such as a patient requiring treatment for cancer. The riminophenazine conveniently may be of the general formula (I). ##STR1## R.sup.1 is a hydrogen atom, a halogen atom or a (C.sub.1 -C.sub.3) alkyl, (C.sub.1 -C.sub.3) alkoxy, fluoromethoxy or trifluoromethyl radical, R.sup.2 is a hydrogen or halogen atom, R.sup.3 is selected from hydrogen, (C.sub.1 -C.sub.4) alkyl, N,N-dialkylamino alkyl, (C.sub.3 -C.sub.12) cycloalkyl, methylcyclohexyl, hydroxycyclohexyl, cycloalkylmethyl, piperidyl, alkyl substituted piperidyl or N-benzyl-substituted pipperidyl, R.sup.4 is a hydrogen or halogen atom or a (C.sub.1 -C.sub.3) alkyl, (C.sub.1 -C.sub.3) alkoxy, fluoromethoxy or trifluoromethyl radical, and n is 1, 2 or 3. The invention also provides novel riminophenazines of general formula (I), their preparation, and compositions containing them.
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: June 9, 1998
    Assignee: Universiteit Van Pretoria
    Inventors: Constance Elizabeth Medlen, Ronald Anderson, John Francis O'Sullivan