Patents by Inventor Constantin Agouridas

Constantin Agouridas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7119180
    Abstract: A subject of the invention is a process for the preparation of the compounds of formula (I): Wherein the substituents are defined as in the application. The compounds of this invention exhibit antibiotic properties.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: October 10, 2006
    Assignee: Aventis Pharma S.A.
    Inventors: Constantin Agouridas, Francois Bretin, Alexis Denis, Claude Fromentin
  • Publication number: 20050065101
    Abstract: A subject of the invention is a process for the preparation of the compounds of formula (I): Wherein the substituents are defined as in the application. The compounds of this invention exhibit antibiotic properties.
    Type: Application
    Filed: November 12, 2004
    Publication date: March 24, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Constantin Agouridas, Francois Bretin, Alexis Denis, Claude Fromentin
  • Patent number: 6455505
    Abstract: A subject of the invention is, as new chemical products, the compounds of formula (I) in which X represents a hydrogen atom or a halogen atom and Z represents a hydrogen atom or the remainder of an acid as well as their addition salts with acids. The compounds of formula (I) have antibiotic properties.
    Type: Grant
    Filed: November 3, 1999
    Date of Patent: September 24, 2002
    Assignee: Hoechst Marion Roussel
    Inventors: Constantin Agouridas, Alexis Denis, Claude Fromentin
  • Publication number: 20020111319
    Abstract: Novel compounds of the formula 1
    Type: Application
    Filed: February 13, 2002
    Publication date: August 15, 2002
    Inventors: Constantin Agouridas, Francois Bretin, Alexis Denis, Claude Fromentin
  • Patent number: 6407257
    Abstract: A subject of the invention is, as new chemical products, the compounds of formula (I) in which X represents a hydrogen atom or a halogen atom and Z represents a hydrogen atom or the remainder of an acid as well as their addition salts with acids. The compounds of formula (I) have antibiotic properties.
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: June 18, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Constantin Agouridas, Alexis Denis, Claude Fromentin
  • Publication number: 20020028781
    Abstract: A subject of the invention is, as new chemical products, the compounds of formula (I) 1
    Type: Application
    Filed: December 11, 2000
    Publication date: March 7, 2002
    Applicant: Hoechst Marion Roussel
    Inventors: Constantin Agouridas, Alexis Denis, Claude Fromentin
  • Patent number: 6352983
    Abstract: Novel compounds of the formula wherein the substituents are defined as in the application having antibiotic properties.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: March 5, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Constantin Agouridas, Francois Bretin, Alexis Denis, Claude Fromentin
  • Publication number: 20020013281
    Abstract: A subject of the invention is, as new chemical products, the compounds of formula (I) 1
    Type: Application
    Filed: November 3, 1999
    Publication date: January 31, 2002
    Inventors: CONSTANTIN AGOURIDAS, ALEXIS DENIS, CLAUDE FROMENTIN
  • Patent number: 6162793
    Abstract: The compounds of formula (I): ##STR1## in which R is a hydrogen atom, an alkyl, optionally substituted by a halogen atom or a (CH.sub.2).sub.m Ar radical or a ##STR2## in which m represents an integer (1-8), n and p, identical or different, represent an integer (0-6), A and B, identical or different, represent a hydrogen or a halogen or an alkyl and Ar represents an aryl or heteroaryl, and Z represents a hydrogen or the remainder of a carboxylic acid, preparation process and use as medicaments.
    Type: Grant
    Filed: February 11, 1999
    Date of Patent: December 19, 2000
    Assignee: Hoechst Marion Roussel
    Inventors: Constantin Agouridas, Jean-Francois Chantot, Alexis Denis, Jean-Marie Pejac
  • Patent number: 6100404
    Abstract: Intermediates for the preparation of compounds selected from the group consisting of a compound of the formula ##STR1## wherein R is ##STR2## n is an integer from 3 to 5, Ar is an optionally substituted heterocyclic selected from the group consisting of
    Type: Grant
    Filed: January 9, 1997
    Date of Patent: August 8, 2000
    Assignee: Hoechst Marion Roussel
    Inventors: Constantin Agouridas, Jean-Francois Chantot, Alexis Denis, Solange Gouin D'Ambrieres, Odile Le Martret
  • Patent number: 6096714
    Abstract: A subject of the invention is the compounds of formula (I): ##STR1## in which: X represents a CH.sub.2 or SO.sub.2 radical or an oxygen atom, Y represents a (CH.sub.2).sub.m --(CH.dbd.CH).sub.n (CH.sub.2).sub.o radical, with m+n+o.ltoreq.8, n=0 or 1, Ar represents an aryl radical,W represents a hydrogen atom, or the remainder of a carbamate function.The compounds of formula (I) have useful antibiotic properties.
    Type: Grant
    Filed: October 9, 1998
    Date of Patent: August 1, 2000
    Assignee: Hoechst Marion Roussel
    Inventors: Constantin Agouridas, Jean-Francois Chantot
  • Patent number: 5786339
    Abstract: A compound selected from the group consisting of a compound of the formula ##STR1## wherein R and R.sub.1 are --OH or --O-acyl of an organic carboxylic acid of 2 to 20 carbon atoms, R.sub.2 is hydrogen or methyl, R.sub.3 is --(CH.sub.2).sub.m --R.sub.4 or ##STR2## or --N--(CH.sub.2).sub.q --R.sub.4, m is an integer from 1 to 6, n, p and q are individually an integer from 0 to 6, A and B are individually selected from the group consisting of hydrogen, halogen and alkyl of 1 to 8 carbon atoms with the geometry of the double bond being E or Z or a mixture of E and Z or A and B form a triple bond, R.sub.4 is an optionally substituted mono- or polycyclic heterocycle and their non-toxic, pharmaceutically acceptable acid addition salts having antibiotic properties.
    Type: Grant
    Filed: November 30, 1995
    Date of Patent: July 28, 1998
    Assignee: Roussel Uclaf
    Inventors: Constantin Agouridas, Jean-Fran.cedilla.ois Chantot
  • Patent number: 5770579
    Abstract: Compounds of the formula ##STR1## wherein X and X' form C.dbd.O or C.dbd.NOR, R is selected from the group consisting of hydrogen, heterocycle, alkyl, alkenyl, alkynyl, all optionally substituted, ##STR2## R.sub.a and R.sub.b are hydrogen or a hydrocarbon group or form together with the nitrogen a heterocycle, or with A forms a 9-N, 11-O ring, and X' is hydrogen, --Y and Y' have the same definition as X and X', b is hydrogen or OR.sub.4, R.sub.4 is hydrogen or forms together with A a carbonate or a carbamate, A forms with C a double bond or A is OR'.sub.4, R'.sub.4 is hydrogen or forms together with B a carbonate or ##STR3## R.sub.2 is alkyl or --CONH.sub.2, --CONHCOR.sub.11 or --CONHSO.sub.2 R.sub.11, R.sub.11 is a hydrocarbon up to 18 carbon atoms, R.sub.3 is hydrogen, ##STR4## and Z is hydrogen or a carboxylic acid remainder and their non-toxic, pharmaceutically acceptable acid addition salts, their preparation and intermediates useful as antibiotics.
    Type: Grant
    Filed: January 25, 1995
    Date of Patent: June 23, 1998
    Assignee: Roussel Uclaf
    Inventors: Constantin Agouridas, Yannick Benedetti, Jean-Fran.cedilla.ois Chantot, Alexis Denis, Claude Fromentin, Odile Le Martret
  • Patent number: 5760233
    Abstract: A compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and an optionally unsaturated hydrocarbon of up to 24 carbon atoms optionally interrupted by at least one heteroatom selected from the group consisting of oxygen, sulfur and nitrogen and optionally having at least one functional group or taken together form ##STR2## and R'.sub.1 and R'.sub.
    Type: Grant
    Filed: February 25, 1997
    Date of Patent: June 2, 1998
    Assignee: Roussel Uclaf
    Inventors: Constantin Agouridas, Yannick Benedetti, Jean-Francois Chantot, Alexis Denis, Odile Le Martret
  • Patent number: 5747467
    Abstract: A compound selected from the group consisting of a compound of the formula ##STR1## wherein X is selected from the group consisting of --(NH).sub.a --, --CH.sub.2 --, --SO.sub.2 -- and --O--, a is 0 or 1, Y is --(CH.sub.2).sub.m - (CH.dbd.CH).sub.n --(CH.sub.2).sub.o -, m+n+o.ltoreq.8, n=o or 1, Ar is aryl optionally substituted with at least one member of the group consisting of --OH, halogen, --NO.sub.2, --CN, ##STR2## and alkyl, alkenyl, alkynyl, alkoxy, alkenyloxy, alkynyloxy, alkylthio, alkenylthio, alkynylthio, -N-alkyl, -N-alkenyl and N-alkynyl of up to 12 carbon atoms, R.sub.a and R.sub.b individually are hydrogen or alkyl of up to 12 carbon atoms, R.sub.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: May 5, 1998
    Assignee: Roussel Uclaf
    Inventors: Constantin Agouridas, Fran.cedilla.ois Bretin, Jean-Fran.cedilla.ois Chantot
  • Patent number: 5656607
    Abstract: A compound selected from the group consisting of a compound of the formula ##STR1## wherein R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and an optionally unsaturated hydrocarbon of up to 24 carbon atoms optionally interrupted by at least one heteroatom selected from the group consisting of oxygen, sulfur and nitrogen and optionally having at least one functional group or taken together form ##STR2## and R'.sub.1 and R'.sub.
    Type: Grant
    Filed: March 31, 1995
    Date of Patent: August 12, 1997
    Assignee: Roussel Uclaf
    Inventors: Constantin Agouridas, Yannick Benedetti, Jean-Francois Chantot, Alexis Denis, Odile Le Martret
  • Patent number: 5635485
    Abstract: An erythromycin compound of Formula I or its non-toxic acid addition salt having antibiotic activity.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: June 3, 1997
    Assignee: Roussel Uclaf
    Inventors: Constantin Agouridas, Jean-Francois Chantot, Alexis Denis, Solange G. D'Ambrieres, Odile L. Martret
  • Patent number: 5614614
    Abstract: Novel intermediates for the preparation of the compounds of Formula I wherein the substituents are as defined in the specification.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: March 25, 1997
    Assignee: Roussel Uclaf
    Inventors: Constantin Agouridas, Alain Bonnefoy, Jean-Francois Chantot, Alexis Denis, Odile Le Martret
  • Patent number: RE39743
    Abstract: Novel compounds of the formula wherein the substituents are defined as in the application having antibiotic properties.
    Type: Grant
    Filed: November 21, 2002
    Date of Patent: July 24, 2007
    Assignee: Aventis Pharma S.A.
    Inventors: Constantin Agouridas, Francois Bretin, Alexis Denis, Claude Fromentin
  • Patent number: RE38520
    Abstract: A subject of the invention is the compounds of formula (I): in which: X represents a CH2 or SO2 radical or an oxygen atom, Y represents a (CH2)m—(CH═CH)n(CH2)o radical, with m+n+o≦8, n=0 or 1, Ar represents an aryl radical, W represents a hydrogen atom, or the remainder of a carbamate function. The compounds of formula (I) have useful antibiotic properties.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: May 18, 2004
    Assignee: Aventis Pharma S.A.
    Inventors: Constantin Agouridas, Jean-Francois Chantot