Patents by Inventor Constantinos Dimas

Constantinos Dimas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical formulations comprising labdanes for the treatment of tumors or leukemias
    Patent number: 6652877
    Abstract: The present invention relates to novel compositions based on hydrated lipidic lamellar phases or liposomal compositions, prepared by combining different lipid molecules, synthetic and/or from natural sources, said compositions comprising at least one of a) labd-13-ene-8&agr;, 15-diol and/or derivatives thereof; b) labd-14-ene-8, 13-diol or derivatives thereof; c) 3&bgr;-hydroxy-labd-14-ene-8, 13-epoxy and/or derivatives thereof, d) a plant extract containing the aforementioned labdenes or derivatives thereof. The compositions of the invention exhibit cytotoxicity against cancerous cells and are utilized for the treatment of tumors and leukemias.
    Type: Grant
    Filed: November 8, 2000
    Date of Patent: November 25, 2003
    Assignee: P.N. Gerolymatos S.A.
    Inventors: Thalia Anastassaki, Demetra Angelopoulou, Demetrios Kokkinopoulos, Constantinos Dimas, Constantinos Demetzos
  • Pharmaceutical formulations comprising labdanes for the treatment of tumors or leukemias
    Patent number: RE39061
    Abstract: The present invention relates to novel compositions based on hydrated lipidic lamellar phases or liposomal compositions, prepared by combining different lipid molecules, synthetic and/or from natural sources, said compositions comprising at least one of a) labd-13-ene-8?, 15-diol and/or derivatives thereof; b) labd-14-ene-8, 13-diol or derivatives thereof; c) 3?-hydroxy-labd-14-ene-8, 13-epoxy and/or derivatives thereof, d) a plant extract containing the aforementioned labdanes or derivatives thereof. The compositions of the invention exhibit cytotoxicity against cancerous cells and are utilized for the treatment of tumors and leukemias.
    Type: Grant
    Filed: October 14, 2004
    Date of Patent: April 11, 2006
    Assignee: Medexis S.A.
    Inventors: Thalia Anastassaki, Demetra Angelopoulou, Demetrios Kokkinopoulos, Constantinos Dimas, Constantinos Demetzos