Patents by Inventor Constantinos Papathomas

Constantinos Papathomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Signaling molecule involved in ultraviolet damage to skin
    Patent number: 9551710
    Abstract: The present invention includes a method of detecting ultraviolet radiation (UVR)-induced skin damage in a mammal. The present invention also includes a method of identifying a mammal at risk of developing UVR-induced skin damage, photoaging, or photocarcinogenesis. The present invention further includes a method of inhibiting UVR-induced skin damage in a mammal at risk of developing UVR-induced skin damage. The present invention also includes a method of reducing the level of Syk kinase in the skin of a mammal. The present invention further includes methods of treating or diagnosing a disease associated with a change of Syk kinase expression in the skin in a mammal.
    Type: Grant
    Filed: February 9, 2011
    Date of Patent: January 24, 2017
    Assignee: Drexel University
    Inventors: Zhenyu Huang, Constantinos Papathomas
  • Antibody immobilization using poly(ethylene glycol) crosslinking
    Patent number: 9134308
    Abstract: Provided is a method for immobilizing a macromolecule to a solid support material using poly(ethylene glycol), and a device obtained from the method. The macromolecule can be a polypeptide, such as an antibody.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: September 15, 2015
    Assignee: Drexel University
    Inventors: David R. Hansberry, Peter M. Clark, Elisabeth Papazoglou, Sundar Babu Nadarajan, Constantinos Papathomas
  • Compositions for inhibiting virus entry and promoting virolysis, and methods thereof
    Patent number: 9114107
    Abstract: The present invention includes a composition comprising a gold nanoparticle complexed with a cysteine-containing compound. The invention also includes the method of preparing a composition comprising a gold nanoparticle complexed with a cysteine-containing compound. The invention further includes a method of causing virolysis of a virus using the compositions described therein. The invention further includes a method of inhibiting virus entry using the compositions described therein.
    Type: Grant
    Filed: October 5, 2011
    Date of Patent: August 25, 2015
    Assignee: Drexel University
    Inventors: Irwin Chaiken, Arangassery Rosemary Bastian, Kantharaju, Constantinos Papathomas
  • ULTRASOUND DEVICE AND THERAPEUTIC METHODS
    Publication number: 20150209564
    Abstract: The present invention is directed to an ultrasound device for use in implementing therapeutic treatments and transdermal analyte delivery. The device includes a piezoelectric transducer that efficiently and safely converts electrical energy to ultrasonic waves, and has a unique structure including a piezoelectric element positioned between two opposing, flexible concave covers. The device may be used for various therapeutic purposes including wound healing, tissue stimulation and transdermal analyte delivery. The invention is further directed to a novel analyte delivery system including the ultrasound device and an encapsulated analyte.
    Type: Application
    Filed: August 28, 2012
    Publication date: July 30, 2015
    Applicant: DREXEL UNIVERSITY
    Inventors: Peter A. Lewin, Constantinos Papathomas, Youhan Sunny, Christopher R. Bawiec, Leonid Zubkov, An Nguyen, Joshua Samuels
  • Antibody Immobilization Using Poly(ethylene glycol) Crosslinking
    Publication number: 20130178587
    Abstract: Provided is a method for immobilizing a macromolecule to a solid support material using poly(ethylene glycol), and a device obtained from the method. The macromolecule can be a polypeptide, such as an antibody.
    Type: Application
    Filed: May 12, 2011
    Publication date: July 11, 2013
    Applicant: Drexel University
    Inventors: David R. Hansberry, Peter M. Clark, Sundar Babu Nadarajan, Constantinos Papathomas