Abstract: A fiducial deployment system may include one or more of a needle including a dimpled retention structure configured to releasably retain a plurality of fiducials, each of which includes a central aperture (which may be embodied as a groove or similar opening); a retention/deployment stylet that traverses through each fiducial's central aperture and releasably engages a distalmost fiducial of the plurality of fiducials with a splayed distal stylet end; a pusher cannula member; and echogenic dimpling and/or other echogenic-enhancing features on at least a distal portion of the needle.