Patents by Inventor Cord F. Stähler
Cord F. Stähler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10876110Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.Type: GrantFiled: March 21, 2017Date of Patent: December 29, 2020Assignee: Codex DNA, Inc.Inventors: Peer F. Staehler, Raphael Carapito, Cord F. Staehler, Mark Matzas, Jack T. Leonard, Joachim Jaeger, Markus Beier
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Publication number: 20170267999Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.Type: ApplicationFiled: March 21, 2017Publication date: September 21, 2017Inventors: Peer F. STAEHLER, Raphael CARAPITO, Cord F. STAEHLER, Mark MATZAS, Jack T. LEONARD, Joachim JAEGER, Markus BEIER
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Publication number: 20170147748Abstract: The invention relates to a method for producing polymers, in particular synthetic nucleic acid double strands of optional sequence, comprising the steps: (a) provision of a support having a surface area which contains a plurality of individual reaction areas, (b) location-resolved synthesis of nucleic acid fragments having in each case different base sequences in several of the individual reaction areas, and (c) detachment of the nucleic acid fragments from individual reaction areas.Type: ApplicationFiled: February 7, 2017Publication date: May 25, 2017Inventors: Peer F. Staehler, Cord F. Staehler, Manfred Mueller
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Patent number: 9568839Abstract: The invention relates to a method for producing polymers, in particular synthetic nucleic acid double strands of optional sequence, comprising the steps: (a) provision of a support having a surface area which contains a plurality of individual reaction areas, (b) location-resolved synthesis of nucleic acid fragments having in each case different base sequences in several of the individual reaction areas, and (c) detachment of the nucleic acid fragments from individual reaction areas.Type: GrantFiled: March 9, 2009Date of Patent: February 14, 2017Assignee: Synthetic Genomics, Inc.Inventors: Peer F. Stähler, Cord F. Stähler, Manfred Müller
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Publication number: 20120071327Abstract: The invention relates to a method for acquisition of genetic information, in particular for personalized medicine.Type: ApplicationFiled: December 11, 2009Publication date: March 22, 2012Applicant: FEBIT HOLDING GMBHInventors: Peer F. Staehler, Cord F. Staehler, Markus Beier, Mark S. Chee, Nadine Schracke
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Publication number: 20120045771Abstract: The invention relates to a method for isolation of target molecules from a nucleic acid population.Type: ApplicationFiled: December 11, 2009Publication date: February 23, 2012Applicant: FEBIT HOLDING GMBHInventors: Markus Beier, Peer F. Staehler, Cord F. Staehler, Daniel Summerer, Jack T. Leonard, Stephan Bau, Anthony Caruso, Nadine Schracke, Andreas Keller, Helmut Hanenberg, Olaf Eckermann
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Patent number: 7901886Abstract: The invention relates to an extraction method for isolating target molecules from a sample using a microfluidic carrier.Type: GrantFiled: November 28, 2007Date of Patent: March 8, 2011Assignee: Febit Holding GmbHInventors: Cord F. Staehler, Peer F. Staehler, Manfred Mueller
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Patent number: 7790369Abstract: The invention relates to a method for producing polymers, in particular synthetic nucleic acid double strands of optional sequence, comprising the steps: (a) providing a support having a surface area which contains a plurality of individual reaction areas, (b) location-resolved synthesizing nucleic acid fragments each having different base sequences in several of the individual reaction areas, and (c) detaching the nucleic acid fragments from individual reaction areas.Type: GrantFiled: June 6, 2003Date of Patent: September 7, 2010Assignee: febit holding GmbHInventors: Peer F. Stähler, Cord F. Stähler, Manfred Müller
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Publication number: 20100216648Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.Type: ApplicationFiled: February 19, 2010Publication date: August 26, 2010Applicant: FEBIT HOLDING GMBHInventors: Peer F. STAEHLER, Raphael CARAPITO, Cord F. STAEHLER, Mark MATZAS, Jack T. LEONARD, Joachim JAEGER, Markus BEIER
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Patent number: 7737088Abstract: The present invention relates to arrays of biochemical and/or biofunctional elements such as nucleic acids (oligonucleotides, for example) or other biomolecules on a carrier surface and methods of producing such arrays using photoactivation of predetermined areas for synthesis using an illumination matrix that is computer-controlled to generate an exposure pattern. This exposure pattern can be adjusted and monitored by computer using a light sensor matrix, for example a CCD matrix, to allow precise, controlled illumination of specific regions and therefore attachment of array building blocks to those specific regions. The methods and compositions of the invention permit spatially resolved photochemical synthesis of polymer probes on a carrier.Type: GrantFiled: August 27, 1999Date of Patent: June 15, 2010Assignee: Febit Holding GmbHInventors: Cord F. Stähler, Peer F. Stähler, Manfred Müller, Fritz Stähler, Hans Lindner
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Patent number: 7470540Abstract: A method for preparing receptor-coated particles is described which comprises the following steps: a) providing a support body, b) conducting a liquid containing particles into or onto the support body, c) immobilizing the particles on at least one surface area of the support body, d) conducting a liquid which contains receptors or receptor building blocks for synthesizing polymeric receptors over the immobilized particles, e) coupling the receptors or receptor building blocks location—or/and time-specifically to the immobilized particles at in each case predetermined positions of the support body, f) repeating, where appropriate, the steps (d) and (e), until the desired receptors have been synthesized on the immobilized particles at the in each case predetermined positions of the support body.Type: GrantFiled: October 17, 2001Date of Patent: December 30, 2008Assignee: Febit AGInventors: Cord F. Stähler, Ramon Güimil, Matthias Scheffler, Peer F. Stähler, Anke Heidbrede
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Patent number: 7320862Abstract: The invention relates to an extraction method for isolating target molecules from a sample using a microfluidic carrier.Type: GrantFiled: October 10, 2002Date of Patent: January 22, 2008Inventors: Cord F. Stähler, Peer F. Stähler, Manfred Müller
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Patent number: 7226862Abstract: In the case of a method for producing a fluid device with a fluid structure having an active height, a basic wafer is provided, which comprises a supporting substrate, an insulating layer on the supporting substrate and a patterned layer on the supporting substrate, the thickness of the patterned layer determining the active height of the fluid structure. Following this, the fluid structure is produced in the patterned layer of the basic wafer, said fluid structure extending through the semiconductor layer. A transparent wafer is then applied so that the fluid structure is covered. Subsequently, the supporting substrate and the insulating layer are removed from the back so that the fluid structure is exposed at a second surface of the patterned layer. Finally, a second transparent wafer is attached to the exposed second surface of the semiconductor layer so that the fluid structure is covered. The essential parameter of the fluid device, viz.Type: GrantFiled: June 4, 2001Date of Patent: June 5, 2007Assignee: Febit Biotech GmbHInventors: Cord F. Staehler, Tilo Strobelt, Johannes Frech, Peter Nommensen, Martin Mueller
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Patent number: 7097974Abstract: A method for producing a support for determining analytes. The method comprises the steps of (a) providing a support comprising at least one channel, comprising a conduit having an intake and an outlet for passing fluid from the intake to the outlet, in the support body, (b) passing liquid with building blocks for synthesizing polymeric receptors through the channel or channels of the support body, (c) site- and/or time-specifically immobilizing the receptor building blocks in each case on predetermined positions in the channel or channels by illumination and (d) repeating steps (b) and (c) until the required receptors have been synthesized in each case on the predetermined positions.Type: GrantFiled: August 27, 1999Date of Patent: August 29, 2006Assignee: febit biotech GmbHInventors: Cord F. Stähler, Peer F. Stähler, Manfred Müller, Fritz Stähler, Hans Lindner
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Patent number: 6586211Abstract: The invention relates to a method for producing polymers, in particular synthetic nucleic acid double strands of optional sequence, comprising the steps: (a) provision of a support having a surface area which contains a plurality of individual reaction areas, (b) location-resolved synthesis of nucleic acid fragments having in each case different base sequences in several of the individual reaction areas, and (c) detachment of the nucleic acid fragments from individual reaction areas.Type: GrantFiled: July 26, 2001Date of Patent: July 1, 2003Assignee: FeBit Ferrarius Biotechnology GmbHInventors: Peer F. Stähler, Cord F. Stähler, Manfred Müller
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Publication number: 20020068021Abstract: In the case of a method for producing a fluid device with a fluid structure having an active height, a basic wafer is provided, which comprises a supporting substrate, an insulating layer on the supporting substrate and a patterned layer on the supporting substrate, the thickness of the patterned layer determining the active height of the fluid structure. Following this, the fluid structure is produced in the patterned layer of the basic wafer, said fluid structure extending through the semiconductor layer. A transparent wafer is then applied so that the fluid structure is covered. Subsequently, the supporting substrate and the insulating layer are removed from the back so that the fluid structure is exposed at a second surface of the patterned layer. Finally, a second transparent wafer is attached to the exposed second surface of the semiconductor layer so that the fluid structure is covered. The essential parameter of the fluid device, viz.Type: ApplicationFiled: June 4, 2001Publication date: June 6, 2002Inventors: Cord F. Staehler, Tilo Strobelt, Johannes Frech, Peter Nommensen, Martin Mueller