Patents by Inventor Corey Brastaad

Corey Brastaad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detecting genetic copy number variation
    Patent number: 12173369
    Abstract: Embodiments of the invention include systems, apparatus, and methods for detecting copy number variation (CNV) in the genomes of one or more patients. Samples of DNA may be taken from several patients, and then sections of the patients' DNA may be sequenced, e.g., through a process that may include, for each patient, one or more of: purifying, concentrating, fragmenting, labeling, filtering, and amplifying that patient's DNA. Fragments from several patients may be pooled, and the fragments in the pool may be sequenced. The sequencing data is then subjected to analysis, which includes several normalization steps. The normalized data are then examined to identify CNV, which is reported.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: December 24, 2024
    Assignee: QUEST DIAGNOSTICS INVESTMENTS INCORPORATED
    Inventors: Corey Brastaad, Christopher D. Elzinga, Mingsheng Zhang, Matthew C. Evans
  • DETECTING GENETIC COPY NUMBER VARIATION
    Publication number: 20200270682
    Abstract: Embodiments of the invention include systems, apparatus, and methods for detecting copy number variation (CNV) in the genomes of one or more patients. Samples of DNA may be taken from several patients, and then sections of the patients' DNA may be sequenced, e.g., through a process that may include, for each patient, one or more of: purifying, concentrating, fragmenting, labeling, filtering, and amplifying that patient's DNA. Fragments from several patients may be pooled, and the fragments in the pool may be sequenced. The sequencing data is then subjected to analysis, which includes several normalization steps. The normalized data are then examined to identify CNV, which is reported.
    Type: Application
    Filed: April 1, 2020
    Publication date: August 27, 2020
    Applicant: QUEST DIAGNOSTICS INVESTMENTS INCORPORATED
    Inventors: Corey Brastaad, Christopher D. Elzinga, Mingsheng Zhang, Matthew C. Evans
  • Detecting genetic copy number variation
    Patent number: 10640823
    Abstract: Embodiments of the invention include systems, apparatus, and methods for detecting copy number variation (CNV) in the genomes of one or more patients. Samples of DNA may be taken from several patients, and then sections of the patients' DNA may be sequenced, e.g., through a process that may include, for each patient, one or more of: purifying, concentrating, fragmenting, labeling, filtering, and amplifying that patient's DNA. Fragments from several patients may be pooled, and the fragments in the pool may be sequenced. The sequencing data is then subjected to analysis, which includes several normalization steps. The normalized data are then examined to identify CNV, which is reported.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: May 5, 2020
    Assignee: QUEST DIAGNOSTICS INVESTMENTS INCORPORATED
    Inventors: Corey Brastaad, Christopher D. Elzinga, Mingsheng Zhang, Matthew C. Evans
  • DETECTING GENETIC COPY NUMBER VARIATION
    Publication number: 20170009287
    Abstract: Embodiments of the invention include systems, apparatus, and methods for detecting copy number variation (CNV) in the genomes of one or more patients. Samples of DNA may be taken from several patients, and then sections of the patients' DNA may be sequenced, e.g., through a process that may include, for each patient, one or more of: purifying, concentrating, fragmenting, labeling, filtering, and amplifying that patient's DNA. Fragments from several patients may be pooled, and the fragments in the pool may be sequenced. The sequencing data is then subjected to analysis, which includes several normalization steps. The normalized data are then examined to identify CNV, which is reported.
    Type: Application
    Filed: July 8, 2015
    Publication date: January 12, 2017
    Applicant: Quest Diagnostics investments Incorporated
    Inventors: Corey Brastaad, Christopher D. Elzinga, Mingsheng Zhang, Matthew C. Evans