Patents by Inventor Corey D. Acker

Corey D. Acker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorinated voltage sensitive dyes, preparation thereof, and optical methods of use
    Patent number: 8993258
    Abstract: A fluorinated voltage sensitive dye has the structure wherein p is 0, 1, or 2; Xq? is an anionic counterion having a charge, q, that is 1 or 2; n is 1 or 2; R1 is an optionally substituted C1-C12, alkyl; R2 is hydrogen, and R3 is hydrogen or fluorine; or R2 and R3 collectively form a divalent —CH?CH—CH?CH— group; R4 and each occurrence of R5 are each independently hydrogen or fluorine; R6 is hydrogen or fluorine or trifluoromethyl; and each occurrence of R7 is independently C1-C6 alkyl; provided that the dye comprises at least one fluorine atom. The dye is particularly useful for monitoring the dynamics of action potentials in axons and/or dendrites.
    Type: Grant
    Filed: June 3, 2013
    Date of Patent: March 31, 2015
    Assignee: The University of Connecticut
    Inventors: Ping Yan, Corey D. Acker, Leslie M. Loew
  • FLUORINATED VOLTAGE SENSITIVE DYES, PREPARATION THEREOF, AND OPTICAL METHODS OF USE
    Publication number: 20130330762
    Abstract: A fluorinated voltage sensitive dye has the structure wherein p is 0, 1, or 2; Xq? is an anionic counterion having a charge, q, that is 1 or 2; n is 1 or 2; R1 is an optionally substituted C1-C12, alkyl; R2 is hydrogen, and R3 is hydrogen or fluorine; or R2 and R3 collectively form a divalent —CH?CH—CH?CH— group; R4 and each occurrence of R5 are each independently hydrogen or fluorine; R6 is hydrogen or fluorine or trifluoromethyl; and each occurrence of R7 is independently C1-C6 alkyl; provided that the dye comprises at least one fluorine atom. The dye is particularly useful for monitoring the dynamics of action potentials in axons and/or dendrites.
    Type: Application
    Filed: June 3, 2013
    Publication date: December 12, 2013
    Applicant: THE UNIVERSITY OF CONNECTICUT
    Inventors: Ping Yan, Corey D. Acker, Leslie M. Loew