Abstract: A prosthetic heart valve delivery system may include a handle, a delivery catheter with an inflatable balloon at a distal end thereof, and a prosthetic heart valve. An axial adjustment actuator may be positioned on the handle for translating the prosthetic heart valve distally or proximally relative to the handle when the prosthetic heart valve is collapsed onto the balloon. A commissure alignment actuator may be positioned on the handle for rotating the prosthetic heart valve about its central longitudinal axis when the prosthetic heart valve is collapsed onto the balloon. The axial adjustment and the commissure alignment actuators may be independently actuated, so that actuation of the axial adjustment actuator does not rotate the prosthetic heart valve, and actuation of the commissure alignment actuator does not translate the prosthetic heart valve.

Abstract: In some embodiments, delivery device includes a delivery catheter, and a handle coupled to the delivery catheter, the handle having a housing and including at least two actuators, each of the at least two actuators being configured to control one of three primary functions, the three primary functions including (1) delivery catheter deflection, (2) delivery catheter axial position fine adjustment, and (3) delivery catheter rotation to achieve native valve commissural alignment.

Abstract: Medical devices for accessing the central nervous system, as well as making and using medical devices, are disclosed. An example medical device may include an expandable access sheath having a proximal end region and a distal end region. The expandable access sheath may be designed to shift between a first configuration and an expanded configuration. The expandable access sheath may include a tubular body having one or more axial support members disposed along the tubular body. The medical device may include an expansion member designed to shift the expandable access sheath between the first configuration and the expanded configuration.

Abstract: Medical devices for accessing the central nervous system, as well as making and using medical devices, are disclosed. An example medical device may include an expandable access sheath having a proximal end region and a distal end region. The expandable access sheath may be designed to shift between a first configuration and an expanded configuration. The expandable access sheath may include a tubular body having one or more axial support members disposed along the tubular body. The medical device may include an expansion member designed to shift the expandable access sheath between the first configuration and the expanded configuration.

Abstract: Medical devices for accessing the central nervous system, as well as making and using medical devices, are disclosed. An example medical device may include an expandable access sheath having a proximal end region and a distal end region. The expandable access sheath may be designed to shift between a first configuration and an expanded configuration. The expandable access sheath may include a tubular body having one or more axial support members disposed along the tubular body. The medical device may include an expansion member designed to shift the expandable access sheath between the first configuration and the expanded configuration.

Abstract: Medical devices for accessing the central nervous system, as well as making and using medical devices, are disclosed. An example medical device may include an expandable access sheath having a proximal end region and a distal end region. The expandable access sheath may be designed to shift between a first configuration and an expanded configuration. The expandable access sheath may include a tubular body having one or more axial support members disposed along the tubular body. The medical device may include an expansion member designed to shift the expandable access sheath between the first configuration and the expanded configuration.

Abstract: Medical devices for accessing the central nervous system, as well as making and using medical devices, are disclosed. An example medical device may include an expandable access sheath having a proximal end region and a distal end region. The expandable access sheath may be designed to shift between a first configuration and an expanded configuration. The expandable access sheath may include a tubular body having one or more axial support members disposed along the tubular body. The medical device may include an expansion member designed to shift the expandable access sheath between the first configuration and the expanded configuration.