Abstract: A method of assessing tear film stability in an ocular surface includes obtaining tear film breakup time data and blink time series for the ocular surface, via one or more imaging assemblies. The method includes converting the tear film breakup time data to a tear film breakup map represented as a polar data array, via a controller, such that respective elements in the polar data array represent a local tear film breakup time at respective radial and angular locations. The blink time series is converted to an interblink interval map such that respective elements in the interblink interval map represent an interblink time interval at different blink completeness levels. The tear film breakup map is integrated with the interblink interval map to generate a tear film stability map. The method includes directing a remedial action when an enabling condition related to the tear film stability map is met.