Patents by Inventor Corinna REBNEGGER

Corinna REBNEGGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CARBON-SOURCE REGULATED PROTEIN PRODUCTION IN A RECOMBINANT HOST CELL
    Publication number: 20240018563
    Abstract: A recombinant host cell comprising an endogenous gene encoding a FLO8 protein comprising the amino acid sequence identified as SEQ ID NO:1 or a homologue thereof, which host cell is engineered by one or more genetic modifications to reduce expression of said gene compared to the host cell prior to said one or more genetic modifications, and which host cell comprises a heterologous expression cassette comprising a gene of interest (GOI) under the control of an expression cassette promoter (ECP) which ECP is repressible by a non-methanol carbon source, and a method of producing a protein of interest using said recombinant host cell.
    Type: Application
    Filed: August 24, 2023
    Publication date: January 18, 2024
    Inventors: Brigitte GASSER, Corinna REBNEGGER, Mirelle Citlali FLORES VILLEGAS, Diethard MATTANOVICH
  • Carbon-source regulated protein production in a recombinant host cell
    Patent number: 11773424
    Abstract: A recombinant host cell comprising an endogenous gene encoding a FLO8 protein comprising the amino acid sequence identified as SEQ ID NO:1 or a homologue thereof, which host cell is engineered by one or more genetic modifications to reduce expression of said gene compared to the host cell prior to said one or more genetic modifications, and which host cell comprises a heterologous expression cassette comprising a gene of interest (GO!) under the control of an expression cassette promoter (ECP) which ECP is repressible by a non-methanol carbon source, and a method of producing a protein of interest using said recombinant host cell.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: October 3, 2023
    Assignee: LONZA LTD
    Inventors: Brigitte Gasser, Corinna Rebnegger, Mirelle Citiali Flores Villegas, Diethard Mattanovich
  • CARBON-SOURCE REGULATED PROTEIN PRODUCTION IN A RECOMBINANT HOST CELL
    Publication number: 20220042064
    Abstract: A recombinant host cell comprising an endogenous gene encoding a FLO8 protein comprising the amino acid sequence identified as SEQ ID NO:1 or a homologue thereof, which host cell is engineered by one or more genetic modifications to reduce expression of said gene compared to the host cell prior to said one or more genetic modifications, and which host cell comprises a heterologous expression cassette comprising a gene of interest (GO!) under the control of an expression cassette promoter (ECP) which ECP is repressible by a non-methanol carbon source, and a method of producing a protein of interest using said recombinant host cell.
    Type: Application
    Filed: January 10, 2020
    Publication date: February 10, 2022
    Inventors: Brigitte GASSER, Corinna REBNEGGER, Mirelle Citiali FLORES VILLEGAS, Diethard MATTANOVICH