Patents by Inventor Corinna X. Chen
Corinna X. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220305057Abstract: The invention provides methods of preparing cellular products to support organ transplantation using hematopoietic cells from deceased donors. The methods include proving to a deceased subject an agent that promotes mobilization of hematopoietic cells from bone marrow to peripheral blood, harvesting hematopoietic cells from the subject, and preparing a cellular product comprising the harvested hematopoietic cells.Type: ApplicationFiled: June 2, 2020Publication date: September 29, 2022Inventors: D. Scott Batty, Jr., Corinna X. Chen
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Publication number: 20220152113Abstract: The invention provides methods of treating non-cancerous disorders in a subject by providing the subject with compositions containing hematopoietic cells. In certain embodiments, the compositions include CD34+ cells and CD3+ cells. In certain embodiments, the compositions include CD34+ cells and facilitating cells. The methods are useful for treating blood cell disorders and other disorders that can be ameliorated by providing donor hematopoietic cells.Type: ApplicationFiled: February 3, 2022Publication date: May 19, 2022Inventors: Steven R. Deitcher, Corinna X. Chen
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Patent number: 11273179Abstract: The invention provides methods of treating non-cancerous disorders in a subject by providing the subject with compositions containing hematopoietic cells. In certain embodiments, the compositions include CD34+ cells and CD3+ cells. In certain embodiments, the compositions include CD34+ cells and facilitating cells. The methods are useful for treating blood cell disorders and other disorders that can be ameliorated by providing donor hematopoietic cells.Type: GrantFiled: March 12, 2019Date of Patent: March 15, 2022Assignee: MEDEOR THERAPEUTICS, INC.Inventors: Steven R. Deitcher, Corinna X. Chen
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Publication number: 20190275085Abstract: The invention provides methods of treating non-cancerous disorders in a subject by providing the subject with compositions containing hematopoietic cells. In certain embodiments, the compositions include CD34+ cells and CD3+ cells. In certain embodiments, the compositions include CD34+ cells and facilitating cells. The methods are useful for treating blood cell disorders and other disorders that can be ameliorated by providing donor hematopoietic cells.Type: ApplicationFiled: March 12, 2019Publication date: September 12, 2019Inventors: Steven R. Deitcher, Corinna X. Chen
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Patent number: 9919151Abstract: Devices, systems and methods for controlling the application of current and/or voltage to deliver drug from patient contacts of an electrotransport drug delivery device by indirectly controlling and/or monitoring the applied current without directly measuring from the cathode of the patient terminal. In particular, described herein are electrotransport drug delivery systems including constant current delivery systems having a feedback current and/or voltage control module that is isolated from the patient contacts (e.g., anodes and cathodes). The feedback module may be isolated by a transistor from the patient contacts; feedback current and/or voltage control measurements may be performed at the transistor rather than at the patient contact (e.g., cathode).Type: GrantFiled: March 5, 2013Date of Patent: March 20, 2018Assignees: Incline Therapeutics, Inc., Alza CorporationInventors: Bradley E. White, Paul Hayter, John Lemke, Scot Satre, Corinna X. Chen, Brian W. Read, Jason E. Dougherty
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Publication number: 20170239468Abstract: A switch-operated therapeutic agent delivery device. Embodiments of the operated therapeutic agent delivery device my include a switch that can be operated by a user, a device controller connected to the switch through a switch input where the device can actuate the device when certain predetermined conditions are met, following performance of both a digital switch validation test and an analog switch validation test. The switch operated therapeutic agent delivery device may have two parts, which are assembled by a user prior to use. These devices may be configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices may indirectly control and/or monitor the applied current without directly measuring from the cathode of the patient terminal.Type: ApplicationFiled: May 8, 2017Publication date: August 24, 2017Inventors: John LEMKE, Scot SATRE, Corinna X. CHEN, Brian W. READ, Zita S. NETZEL, David SEWARD, Bradley E. WHITE, Paul HAYTER, Jason E. DOUGHERTY
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Patent number: 9731121Abstract: A switch-operated therapeutic agent delivery device is described. Embodiments of the operated therapeutic agent delivery device include a switch that can be operated by a user, a device controller connected to the switch through a switch input where the device can actuate the device when certain predetermined conditions are met, following performance of both a digital switch validation test and an analog switch validation test.Type: GrantFiled: June 4, 2014Date of Patent: August 15, 2017Assignee: Incline Therapeutics, Inc.Inventors: John Lemke, Scot Satre, Corinna X. Chen, Brian W. Read, Jason E. Dougherty, Nitin B. Joshi
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Patent number: 9645179Abstract: Electrotransport drug delivery devices, system and methods of using configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices/systems may include an off-current module to determine that any current (e.g., which may be inferred by measuring potential difference between the anode and cathode of the device) flowing between the anode and cathode is below a threshold value when the device is not supposed to be delivering drug, thereby preventing unintended delivery of drug and/or alerting a user that unintended delivery of drug may occur.Type: GrantFiled: July 31, 2015Date of Patent: May 9, 2017Assignees: Incline Therapeutics, Inc., Alza CorporationInventors: Bradley E. White, John Lemke, Paul Hayter, Corinna X. Chen, Brian W. Read, Jason E. Dougherty
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Publication number: 20160296750Abstract: A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.Type: ApplicationFiled: June 13, 2016Publication date: October 13, 2016Inventors: Zita S. NETZEL, John LEMKE, David SEWARD, Brian W. READ, Bradley E. WHITE, Corinna X. CHEN, Paul HAYTER
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Patent number: 9364656Abstract: A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.Type: GrantFiled: March 9, 2012Date of Patent: June 14, 2016Assignees: Incline Therapeutics, Inc., Alza CorporationInventors: Zita S. Netzel, John Lemke, David Seward, Brian W. Read, Bradley E. White, Corinna X. Chen, Paul Hayter
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Publication number: 20150338445Abstract: Electrotransport drug delivery devices, system and methods of using configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices/systems may include an off-current module to determine that any current (e.g., which may be inferred by measuring potential difference between the anode and cathode of the device) flowing between the anode and cathode is below a threshold value when the device is not supposed to be delivering drug, thereby preventing unintended delivery of drug and/or alerting a user that unintended delivery of drug may occur.Type: ApplicationFiled: July 31, 2015Publication date: November 26, 2015Inventors: Bradley E. WHITE, John LEMKE, Paul HAYTER, Corinna X. CHEN, Brian W. READ, Jason E. DOUGHERTY
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Patent number: 9095706Abstract: Electrotransport drug delivery devices, system and methods of using configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices/systems may include an off-current module to determine that any current (e.g., which may be inferred by measuring potential difference between the anode and cathode of the device) flowing between the anode and cathode is below a threshold value when the device is not supposed to be delivering drug, thereby preventing unintended delivery of drug and/or alerting a user that unintended delivery of drug may occur.Type: GrantFiled: April 19, 2013Date of Patent: August 4, 2015Assignees: Incline Therapeutics, Inc., Alza CorporationInventors: Bradley E. White, John Lemke, Paul Hayter, Corinna X. Chen, Brian W. Read, Jason E. Dougherty
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Publication number: 20150196754Abstract: Devices, systems and methods for controlling the application of current and/or voltage to deliver drug from patient contacts of an electrotransport drug delivery device by indirectly controlling and/or monitoring the applied current without directly measuring from the cathode of the patient terminal. In particular, described herein are electrotransport drug delivery systems including constant current delivery systems having a feedback current and/or voltage control module that is isolated from the patient contacts (e.g., anodes and cathodes). The feedback module may be isolated by a transistor from the patient contacts; feedback current and/or voltage control measurements may be performed at the transistor rather than at the patient contact (e.g., cathode).Type: ApplicationFiled: March 5, 2013Publication date: July 16, 2015Applicants: ALZA CORPORATION, INCLINE THERAPEUTICS, INC.Inventors: Bradley E. White, Paul Hayter, John Lemke, Scot Satre, Corinna X. Chen, Brian W. Read, Jason E. Dougherty
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Publication number: 20140288526Abstract: A switch-operated therapeutic agent delivery device is described. Embodiments of the operated therapeutic agent delivery device include a switch that can be operated by a user, a device controller connected to the switch through a switch input where the device can actuate the device when certain predetermined conditions are met, following performance of both a digital switch validation test and an analog switch validation test.Type: ApplicationFiled: June 4, 2014Publication date: September 25, 2014Inventors: John LEMKE, Scot SATRE, Corinna X. CHEN, Brian W. READ, Jason E. Dougherty, Nitin B. Joshi
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Patent number: 8781571Abstract: A switch operated therapeutic agent delivery device is described. Embodiments of the operated therapeutic agent delivery device include a switch that can be operated by a user, a device controller connected to the switch through a switch input where the device can actuate the device when certain predetermined conditions are met, and a switch integrity subcircuit which is used to detect a fault or a precursor to a fault.Type: GrantFiled: September 30, 2011Date of Patent: July 15, 2014Assignee: Incline Therapeutics, Inc.Inventors: John Lemke, Scot Satre, Corinna X. Chen, Brian W. Read
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Publication number: 20140115882Abstract: A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.Type: ApplicationFiled: March 9, 2012Publication date: May 1, 2014Inventors: Zita S. Netzel, John Lemke, David Seward, Brian W. Read, Bradley E. White, Corinna X. Chen, Paul Hayter
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Publication number: 20130310729Abstract: Electrotransport drug delivery devices, system and methods of using configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices/systems may include an off-current module to determine that any current (e.g., which may be inferred by measuring potential difference between the anode and cathode of the device) flowing between the anode and cathode is below a threshold value when the device is not supposed to be delivering drug, thereby preventing unintended delivery of drug and/or alerting a user that unintended delivery of drug may occur.Type: ApplicationFiled: April 19, 2013Publication date: November 21, 2013Inventors: Bradley E. WHITE, John LEMKE, Paul HAYTER, Corinna X. CHEN, Brian W. READ, Jason E. DOUGHERTY
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Patent number: 8428709Abstract: Devices, systems and methods for controlling the application of current and/or voltage to deliver drug from patient contacts of an electrotransport drug delivery device by indirectly controlling and/or monitoring the applied current without directly measuring from the cathode of the patient terminal. In particular, described herein are electrotransport drug delivery systems including constant current delivery systems having a feedback current and/or voltage control module that is isolated from the patient contacts (e.g., anodes and cathodes). The feedback module may be isolated by a transistor from the patient contacts; feedback current and/or voltage control measurements may be performed at the transistor rather than at the patient contact (e.g., cathode).Type: GrantFiled: June 11, 2012Date of Patent: April 23, 2013Assignees: Incline Therapeutics, Inc., Alza CorporationInventors: Bradley E. White, Paul Hayter, John Lemke, Scot Satre, Corinna X. Chen, Brian W. Read, Jason E. Dougherty
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Patent number: 8428708Abstract: Electrotransport drug delivery devices, system and methods of using configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices/systems may include an off-current module to determine that any current (e.g., which may be inferred by measuring potential difference between the anode and cathode of the device) flowing between the anode and cathode is below a threshold value when the device is not supposed to be delivering drug, thereby preventing unintended delivery of drug and/or alerting a user that unintended delivery of drug may occur.Type: GrantFiled: May 21, 2012Date of Patent: April 23, 2013Assignees: Incline Therapeutics, Inc., Alza CorporationInventors: Bradley E. White, John Lemke, Paul Hayter, Corinna X. Chen, Brian W. Read, Jason E. Dougherty
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Patent number: 8301238Abstract: A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.Type: GrantFiled: September 30, 2011Date of Patent: October 30, 2012Assignees: Incline Therapeutics, Inc., Alza CorporationInventors: Zita S. Netzel, John Lemke, David Seward, Brian W. Read, Bradley E. White, Corinna X. Chen, Paul Hayter