Patents by Inventor Corinne Bright

Corinne Bright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190216899
    Abstract: Methods, devices and systems are described for decreasing the activity of the sympathetic nervous innervation to and from the lungs and the vessels supplying the lungs to treat pulmonary medical conditions such as asthma. In one embodiment, the method may involve advancing an intravascular instrument to a target location in a blood vessel within the intercostal vasculature to ablate either or both the sympathetic afferent and efferent nerves lying within the paravertebral gutter including the visceral fibers that travel to the cardiothoracic cavity and abdominopelvic viscera and the T1 to T4/5 sympathetic chain. In another embodiment, an intravascular instrument may be advanced to the bronchial vessels to ablate either or both the sympathetic afferent and efferent nerves in and around the posterior pulmonary plexus. In one embodiment the ablative agent is a neurolytic agent delivered in a gel. This approach may be utilized to treat other cardiac and pulmonary diseases.
    Type: Application
    Filed: February 13, 2019
    Publication date: July 18, 2019
    Inventor: Corinne Bright
  • Publication number: 20190038646
    Abstract: Methods, agents, and devices to treat medical conditions through local chemical neuromodulation of the autonomic nervous system are described. Drug formulations may be injected at or near ganglia, nerve plexi, ganglionated plexi, and nerves to treat different diseases. Target sites for the treatment of cardiac and other disease conditions may include extrinsic stellate (cervicothoracic) and cervical ganglia of the sympathetic chain, and intrinsic cardiac nerves and ganglionated plexi innervating the myocardium.
    Type: Application
    Filed: February 9, 2017
    Publication date: February 7, 2019
    Inventors: Corinne Bright, Kondapavulur T. Venkateswara-Rao, Emily Stein
  • Publication number: 20180311164
    Abstract: Described here are various compositions for the delivery active agents, e.g., antifungal agents. The compositions may be beneficial due to the particular release kinetics associated with them. Various locations and methods for placement of the compositions into the tissues of the nail unit, as well as tissues surrounding the nail milt are also described.
    Type: Application
    Filed: July 2, 2018
    Publication date: November 1, 2018
    Inventors: Corinne Bright, Jinping Wan, Martin Babler, Ayse Zamboglu
  • Publication number: 20180147260
    Abstract: Methods, devices and systems are described for decreasing the activity of the sympathetic nervous innervation to and from the lungs and the vessels supplying the lungs to treat pulmonary medical conditions such as asthma. In one embodiment, the method may involve advancing an intravascular instrument to a target location in a blood vessel within the intercostal vasculature to ablate either or both the sympathetic afferent and efferent nerves lying within the paravertebral gutter including the visceral fibers that travel to the cardiothoracic cavity and abdominopelvic viscera and the T1 to T4/5 sympathetic chain. In another embodiment, an intravascular instrument may be advanced to the bronchial vessels to ablate either or both the sympathetic afferent and efferent nerves in and around the posterior pulmonary plexus. In one embodiment the ablative agent is a neurolytic agent delivered in a gel. This approach may be utilized to treat other cardiac and pulmonary diseases.
    Type: Application
    Filed: December 20, 2017
    Publication date: May 31, 2018
    Inventor: Corinne Bright
  • Publication number: 20180116960
    Abstract: Described here are various compositions for the delivery active agents, e.g., antifungal agents. The compositions may be beneficial due to the particular release kinetics associated with them. Various locations and methods for placement of the compositions into the tissues of the nail unit, as well as tissues surrounding the nail milt are also described.
    Type: Application
    Filed: December 28, 2017
    Publication date: May 3, 2018
    Inventors: Corinne Bright, Jinping Wan, Martin Babler, Ayse Zamboglu
  • Patent number: 9855317
    Abstract: Methods, devices and systems are described for decreasing the activity of the sympathetic nervous innervation to and from the lungs and the vessels supplying the lungs to treat pulmonary medical conditions such as asthma. In one embodiment, the method may involve advancing an intravascular instrument to a target location in a blood vessel within the intercostal vasculature to ablate either or both the sympathetic afferent and efferent nerves lying within the paravertebral gutter including the visceral fibers that travel to the cardiothoracic cavity and abdominopelvic viscera and the T1 to T4/5 sympathetic chain. In another embodiment, an intravascular instrument may be advanced to the bronchial vessels to ablate either or both the sympathetic afferent and efferent nerves in and around the posterior pulmonary plexus. In one embodiment the ablative agent is a neurolytic agent delivered in a gel. This approach may be utilized to treat other cardiac and pulmonary diseases.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: January 2, 2018
    Assignee: Reflex Medical, Inc.
    Inventor: Corinne Bright
  • Publication number: 20170340565
    Abstract: Described here are various compositions for the delivery active agents, e.g., antifungal agents. The compositions may be beneficial due to the particular release kinetics associated with them. Various locations and methods for placement of the compositions into the tissues of the nail unit, as well as tissues surrounding the nail milt are also described.
    Type: Application
    Filed: July 10, 2017
    Publication date: November 30, 2017
    Inventors: Corinne Bright, Jinping Wan, Martin Babler, Ayse Zamboglu
  • Patent number: 9737486
    Abstract: A method for protection of tissues subject to ischemic and/or reperfusion damage is provided. The method includes administering to the tissue a composition comprising nanodevices. The nanodevices can take the form of, for example, polymeric nanoparticles or lipidic nanoparticles. The nanodevices also find use in methods for reducing ischemic injury in tissue at risk of such injury, such as heart and brain tissue.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: August 22, 2017
    Assignees: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE JOHNS HOPKINS UNIVERSITY
    Inventors: Corinne Bright, Rachel Bright, Eric Churchill, Kam W. Leong, Daria Mochly-Rosen
  • Publication number: 20160317621
    Abstract: Methods, devices and systems are described for decreasing the activity of the sympathetic nervous innervation to and from the lungs and the vessels supplying the lungs to treat pulmonary medical conditions such as asthma. In one embodiment, the method may involve advancing an intravascular instrument to a target location in a blood vessel within the intercostal vasculature to ablate either or both the sympathetic afferent and efferent nerves lying within the paravertebral gutter including the visceral fibers that travel to the cardiothoracic cavity and abdominopelvic viscera and the T1 to T4/5 sympathetic chain. In another embodiment, an intravascular instrument may be advanced to the bronchial vessels to ablate either or both the sympathetic afferent and efferent nerves in and around the posterior pulmonary plexus. In one embodiment the ablative agent is a neurolytic agent delivered in a gel. This approach may be utilized to treat other cardiac and pulmonary diseases.
    Type: Application
    Filed: April 27, 2016
    Publication date: November 3, 2016
    Inventor: Corinne Bright
  • Patent number: 9446009
    Abstract: The biodegradable drug delivery systems described here are formulated for implantation into the nail unit and its surrounding tissues for the treatment of various nail unit conditions. The systems include non-temperature dependent phase change compositions that may be formulated as solutions, solids, semisolids, microparticles, or crystals.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: September 20, 2016
    Assignee: Hallux, Inc.
    Inventors: Frank Kochinke, Corinne Bright
  • Publication number: 20140322293
    Abstract: The biodegradable drug delivery systems described here are formulated for implantation into the nail unit and its surrounding tissues for the treatment of various nail unit conditions. The systems include non-temperature dependent phase change compositions that may be formulated as solutions, solids, semisolids, microparticles, or crystals.
    Type: Application
    Filed: April 29, 2014
    Publication date: October 30, 2014
    Applicant: Hallux, Inc.
    Inventors: Frank Kochinke, Corinne Bright
  • Publication number: 20140178465
    Abstract: A method for protection of tissues subject to ischemic and/or reperfusion damage is provided. The method includes administering to the tissue a composition comprising nanodevices. The nanodevices can take the form of, for example, polymeric nanoparticles or lipidic nanoparticles. The nanodevices also find use in methods for reducing ischemic injury in tissue at risk of such injury, such as heart and brain tissue.
    Type: Application
    Filed: February 28, 2014
    Publication date: June 26, 2014
    Applicants: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, JOHNS HOPKINS UNIVERSITY
    Inventors: Corinne Bright, Rachel Bright, Eric Churchill, Kam W. Leong, Daria Mochly-Rosen
  • Patent number: 8747820
    Abstract: The biodegradable drug delivery systems described here are formulated for implantation into the nail unit and its surrounding tissues for the treatment of various nail unit conditions. The systems include non-temperature dependent phase change compositions that may be formulated as solutions, solids, semisolids, microparticles, or crystals.
    Type: Grant
    Filed: October 23, 2013
    Date of Patent: June 10, 2014
    Assignee: Hallux, Inc.
    Inventors: Frank Kochinke, Corinne Bright
  • Patent number: 8697120
    Abstract: A method for protection of tissues subject to ischemic and/or reperfusion damage is provided. The method includes administering to the tissue a composition comprising nanodevices. The nanodevices can take the form of, for example, polymeric nanoparticles or lipidic nanoparticles. The nanodevices also find use in methods for reducing ischemic injury in tissue at risk of such injury, such as heart and brain tissue.
    Type: Grant
    Filed: May 1, 2007
    Date of Patent: April 15, 2014
    Assignees: Johns Hopkins University, The Board of Trustees of the Leland Stanford Junior University
    Inventors: Corinne Bright, Rachel Bright, Eric Churchill, Kam W. Leong, Daria Mochly-Rosen
  • Patent number: 8591870
    Abstract: The biodegradable drug delivery systems described here are formulated for implantation into the nail unit and its surrounding tissues for the treatment of various nail unit conditions. The systems include non-temperature dependent phase change compositions that may be formulated as solutions, solids, semisolids, microparticles, or crystals.
    Type: Grant
    Filed: January 6, 2011
    Date of Patent: November 26, 2013
    Assignee: Hallux, Inc.
    Inventors: Frank Kochinke, Corinne Bright
  • Publication number: 20130122097
    Abstract: Described here are various compositions for the delivery active agents, e.g., antifungal agents. The compositions may be beneficial due to the particular release kinetics associated with them. Various locations and methods for placement of the compositions into the tissues of the nail unit, as well as tissues surrounding the nail unit are also described.
    Type: Application
    Filed: December 22, 2010
    Publication date: May 16, 2013
    Applicant: HALLUX, INC.
    Inventors: Corinne Bright, Jinping Wan, Martin Babler, Ayse Zamboglu
  • Patent number: 8354095
    Abstract: The biodegradable drug delivery systems described here are formulated for implantation into the nail unit and its surrounding tissues for the treatment of various nail unit conditions. The systems include greater than 30% by weight of the active agent, and may be formulated as solutions, solids, semisolids, microparticles, or crystals. Methods related to the implantation and use of the biodegradable drug delivery systems for treating nail unit conditions are also described.
    Type: Grant
    Filed: February 11, 2008
    Date of Patent: January 15, 2013
    Assignee: Hallux, Inc.
    Inventors: Frank M. Kochinke, Corinne Bright
  • Publication number: 20110104235
    Abstract: The biodegradable drug delivery systems described here are formulated for implantation into the nail unit and its surrounding tissues for the treatment of various nail unit conditions. The systems include non-temperature dependent phase change compositions that may be formulated as solutions, solids, semisolids, microparticles, or crystals.
    Type: Application
    Filed: January 6, 2011
    Publication date: May 5, 2011
    Inventors: Frank Kochinke, Corinne Bright
  • Publication number: 20080132442
    Abstract: The biodegradable drug delivery systems described here are formulated for implantation into the nail unit and its surrounding tissues for the treatment of various nail unit conditions. The systems include greater than 30% by weight of the active agent, and may be formulated as solutions, solids, semisolids, microparticles, or crystals. Methods related to the implantation and use of the biodegradable drug delivery systems for treating nail unit conditions are also described.
    Type: Application
    Filed: February 11, 2008
    Publication date: June 5, 2008
    Inventors: Frank M. Kochinke, Corinne Bright
  • Publication number: 20070259032
    Abstract: A method for protection of tissues subject to ischemic and/or reperfusion damage is provided. The method includes administering to the tissue a composition comprising nanodevices. The nanodevices can take the form of, for example, polymeric nanoparticles or lipidic nanoparticles. The nanodevices also find use in methods for reducing ischemic injury in tissue at risk of such injury, such as heart and brain tissue.
    Type: Application
    Filed: May 1, 2007
    Publication date: November 8, 2007
    Inventors: Corinne Bright, Rachel Bright, Eric Churchill, Kam Leong, Daria Rosen