Patents by Inventor Cornelia Bengea

Cornelia Bengea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS TO CONTROL PROTEIN HETEROGENEITY
    Publication number: 20170198034
    Abstract: The instant invention relates to the field of protein production and in particular to controlled protein heterogeneity compositions and processes for controlling the heterogeneity of proteins expressed in host cells.
    Type: Application
    Filed: December 2, 2016
    Publication date: July 13, 2017
    Inventors: Lisa M. Rives, Cornelia Bengea, Xiaobei Zeng
  • METHODS TO CONTROL PROTEIN HETEROGENEITY
    Publication number: 20170137496
    Abstract: The instant invention relates to the field of protein production, and in particular to compositions and processes for controlling and limiting the heterogeneity of proteins expressed in host cells.
    Type: Application
    Filed: January 27, 2017
    Publication date: May 18, 2017
    Applicant: AbbVie Inc.
    Inventors: Lisa M. Rives, Cornelia Bengea, Xiaobei Zeng
  • METHODS FOR CONTROLLING THE GALACTOSYLATION PROFILE OF RECOMBINANTLY-EXPRESSED PROTEINS
    Publication number: 20170051052
    Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g.
    Type: Application
    Filed: November 8, 2016
    Publication date: February 23, 2017
    Inventors: Cornelia Bengea, Lisa M. Rives, Patrick Hossler
  • Methods to control protein heterogeneity
    Patent number: 9512214
    Abstract: The instant invention relates to the field of protein production and in particular to controlled protein heterogeneity compositions and processes for controlling the heterogeneity of proteins expressed in host cells.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: December 6, 2016
    Assignee: AbbVie, Inc.
    Inventors: Lisa M. Rives, Cornelia Bengea, Xiaobei Zeng
  • Methods for controlling the galactosylation profile of recombinantly-expressed proteins
    Patent number: 9505834
    Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: November 29, 2016
    Assignee: AbbVie Inc.
    Inventors: Cornelia Bengea, Lisa M. Rives, Patrick Hossler
  • METHODS FOR CONTROLLING THE GALACTOSYLATION PROFILE OF RECOMBINANTLY-EXPRESSED PROTEINS
    Publication number: 20160207992
    Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g.
    Type: Application
    Filed: March 31, 2016
    Publication date: July 21, 2016
    Inventors: Cornelia Bengea, Lisa M. Rives, Patrick Hossler
  • Methods for controlling the galactosylation profile of recombinantly-expressed proteins
    Patent number: 9365645
    Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g., a hydrolysate-based or a chemically defined medium, with manganese and/or D-galactose.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: June 14, 2016
    Assignee: AbbVie, Inc.
    Inventors: Cornelia Bengea, Lisa M. Rives, Patrick Hossler
  • METHODS FOR CONTROLLING THE GALACTOSYLATION PROFILE OF RECOMBINANTLY-EXPRESSED PROTEINS
    Publication number: 20160152702
    Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g.
    Type: Application
    Filed: February 3, 2016
    Publication date: June 2, 2016
    Inventors: Cornelia Bengea, Lisa M. Rives, Patrick Hossler
  • METHODS TO CONTROL PROTEIN HETEROGENEITY
    Publication number: 20160138064
    Abstract: The instant invention relates to the field of protein production, and in particular to compositions and processes for controlling and limiting the heterogeneity of proteins expressed in host cells.
    Type: Application
    Filed: December 3, 2015
    Publication date: May 19, 2016
    Inventors: Lisa M. Rives, Cornelia Bengea, Xiaobei Zeng
  • Methods to control protein heterogeneity
    Patent number: 9290568
    Abstract: The instant invention relates to the field of protein production and in particular to controlled protein heterogeneity compositions and processes for controlling the heterogeneity of proteins expressed in host cells.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: March 22, 2016
    Assignee: AbbVie, Inc.
    Inventors: Lisa M. Rives, Cornelia Bengea, Xiaobei Zeng
  • Methods for controlling the galactosylation profile of recombinantly-expressed proteins
    Patent number: 9255143
    Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g., a hydrolysate-based or a chemically defined medium, with manganese and/or D-galactose.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: February 9, 2016
    Assignee: AbbVie Inc.
    Inventors: Cornelia Bengea, Lisa M. Rives, Patrick Hossler
  • Methods to control protein heterogeneity
    Patent number: 9234033
    Abstract: The instant invention relates to the field of protein production and in particular to controlled protein heterogeneity compositions and processes for controlling the heterogeneity of proteins expressed in host cells.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: January 12, 2016
    Assignee: AbbVie, Inc.
    Inventors: Lisa M. Rives, Cornelia Bengea, Xiaobei Zeng
  • Methods to control protein heterogeneity
    Patent number: 9206390
    Abstract: The instant invention relates to the field of protein production, and in particular to compositions and processes for controlling and limiting the heterogeneity of proteins expressed in host cells.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 8, 2015
    Assignee: AbbVie, Inc.
    Inventors: Lisa M. Rives, Cornelia Bengea, Xiaobei Zeng
  • Methods for controlling the galactosylation profile of recombinantly-expressed proteins
    Patent number: 9090688
    Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g., a hydrolysate-based or a chemically defined medium, with manganese and/or D-galactose.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: July 28, 2015
    Assignee: AbbVie Inc.
    Inventors: Cornelia Bengea, Lisa M. Rives, Patrick Hossler
  • METHODS TO CONTROL PROTEIN HETEROGENEITY
    Publication number: 20150183866
    Abstract: The instant invention relates to the field of protein production and in particular to controlled protein heterogeneity compositions and processes for controlling the heterogeneity of proteins expressed in host cells.
    Type: Application
    Filed: February 26, 2015
    Publication date: July 2, 2015
    Inventors: Lisa M. Rives, Cornelia Bengea, Xiaobei Zeng
  • METHODS TO CONTROL PROTEIN HETEROGENEITY
    Publication number: 20150183865
    Abstract: The instant invention relates to the field of protein production and in particular to controlled protein heterogeneity compositions and processes for controlling the heterogeneity of proteins expressed in host cells.
    Type: Application
    Filed: February 26, 2015
    Publication date: July 2, 2015
    Inventors: Lisa M. Rives, Cornelia Bengea, Xiaobei Zeng
  • Methods for controlling the galactosylation profile of recombinantly-expressed proteins
    Patent number: 9062106
    Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g., a hydrolysate-based or a chemically defined medium, with manganese and/or D-galactose.
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: June 23, 2015
    Assignee: AbbVie Inc.
    Inventors: Cornelia Bengea, Lisa M. Rives, Patrick Hossler
  • METHODS FOR CONTROLLING THE GALACTOSYLATION PROFILE OF RECOMBINANTLY-EXPRESSED PROTEINS
    Publication number: 20150158944
    Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g., a hydrolysate-based or a chemically defined medium, with manganese and/or D-galactose.
    Type: Application
    Filed: February 11, 2015
    Publication date: June 11, 2015
    Inventors: Cornelia Bengea, Lisa M. Rives
  • METHODS FOR CONTROLLING THE GALACTOSYLATION PROFILE OF RECOMBINANTLY-EXPRESSED PROTEINS
    Publication number: 20150050693
    Abstract: The present invention relates to methods for modulating the glycosylation profile of recombinantly-expressed proteins. In particular, the present invention relates to methods of controlling the galactosylation profile of recombinantly-expressed proteins by supplementing production medium, e.g., a hydrolysate-based or a chemically defined medium, with manganese and/or D-galactose.
    Type: Application
    Filed: September 22, 2014
    Publication date: February 19, 2015
    Inventors: Cornelia Bengea, Lisa M. Rives
  • METHODS TO CONTROL PROTEIN HETEROGENEITY
    Publication number: 20140314745
    Abstract: The instant invention relates to the field of protein production and in particular to controlled protein heterogeneity compositions and processes for controlling the heterogeneity of proteins expressed in host cells.
    Type: Application
    Filed: February 28, 2014
    Publication date: October 23, 2014
    Applicant: ABBVIE INC.
    Inventors: Lisa M. Rives, Cornelia Bengea, Xiaobei Zeng