Patents by Inventor Cornelia Dorner-Ciossek

Cornelia Dorner-Ciossek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted ethane-1,2-diamines for the treatment of Alzheimer's disease
    Publication number: 20060025345
    Abstract: The invention relates to a compound of the formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, A, B, and Y are defined as in the specification and claims and to its use for treating or preventing Alzheimer's disease and other similar diseases.
    Type: Application
    Filed: May 20, 2005
    Publication date: February 2, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Stefan Peters, Christian Eickmeier, Klaus Fuchs, Werner Stransky, Cornelia Dorner-Ciossek, Marcus Kostka, Sandra Handschuh, Margit Bauer, Herbert Nar, Klaus Bornemann, Klaus Klinder, Joerg Rademann, Steffen Weik
  • Method of treating diseases and conditions associated with an altered level of amyloid beta peptides and new enolcarboxamide compounds
    Publication number: 20050277635
    Abstract: A method of treating or preventing of a disease or condition associated with an increased level of isoforms of amyloid ? peptides (A?) and/or with a changed ratio of levels of A? isoforms and/or with the formation of plaques containing amyloid ? peptide (A?) isoforms in a mammal comprising administering to said mammal an therapeutically effective amount of a compound selected from the formulas Ia, Ib wherein V, W, Y, R2, R3, R5, R6, L1 and i are defined as in claim 1.
    Type: Application
    Filed: May 19, 2005
    Publication date: December 15, 2005
    Applicants: Boehringer Ingelheim International GmbH, Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Klaus Bornemann, Guenter Trummlitz, Bernd Beck, Frank Sams-Dodd, Dagmar Kugler, Klaus Klinder, Cornelia Dorner-Ciossek, Marcus Kostka
  • Trisubstituted pyrimidines
    Publication number: 20050090486
    Abstract: The present invention relates to trisubstituted pyrimidines of formula wherein Ra to Re are defined as in claim 1, which are suitable for the treatment of illnesses in which ?-amyloid modulators have a therapeutic benefit, the use thereof for preparing a pharmaceutical composition with the abovementioned properties, and processes for the preparation thereof.
    Type: Application
    Filed: December 9, 2004
    Publication date: April 28, 2005
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Klaus Bornemann, Hans Briem, Cornelia Dorner-Ciossek, Katja Fechteler, Klaus Fuchs, Frank Himmelsbach, Klaus Klinder, Markus Kostka
  • Muscarinic M1 agonist as an inhibitor of beta-amyloid (A&bgr;40 and A&bgr;42)-synthesis
    Patent number: 6573276
    Abstract: Methods of lowering the levels of A&bgr;40, A&bgr;42 and tau protein in a mammal comprising administering to the mammal an effective amount of talsaclidine, or a physiologically acceptable acid addition salt thereof, and methods of treating diseases associated with the formation of diffuse and senile plaques or A&bgr;40-, A&bgr;42- and tau-containing plaques are disclosed.
    Type: Grant
    Filed: April 30, 2002
    Date of Patent: June 3, 2003
    Assignee: Boehringer Ingelheim Pharma KG
    Inventors: Christoph Hock, Andreas Raschig, Marion Wienrich, Roger Nitsch, Klaus Mendla, Dieter Horst Meier, Klaus Bornemann, Cornelia Dorner-Ciossek
  • Muscarinic M1 agonist as an inhibitor of beta-amyloid (ABeta40 and ABeta42)-synthesis
    Publication number: 20030050221
    Abstract: A method of lowering the levels of A&bgr;40, A&bgr;42, and tau protein in a mammal comprising administering to the mammal an effective amount of talsaclidine or a physiologically acceptable acid addition salt thereof and methods of treating or preventing diseases associated with the formation of diffuse and senile plaques or A&bgr;40-, A&bgr;42- and tau-containing plaques.
    Type: Application
    Filed: April 30, 2002
    Publication date: March 13, 2003
    Inventors: Christoph Hock, Andreas Raschig, Marion Wienrich, Roger Nitsch, Klaus Mendla, Dieter Horst Meier, Klaus Bornemann, Cornelia Dorner-Ciossek
  • Gamma-secretase in vitro screening assay
    Publication number: 20030022251
    Abstract: According to the screening method of the invention substances capable of modulating &ggr;-secretase activity are identified by incubating a source and a substrate of &ggr;-secretase activity with a test substance and detecting a C-terminal fragment released from said substrate.
    Type: Application
    Filed: June 26, 2002
    Publication date: January 30, 2003
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Klaus Fuchs, Cornelia Dorner-Ciossek, Marcus Kostka, Christian Haass, Harald Steiner