Patents by Inventor Cornelia KAINTZ

Cornelia KAINTZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for improving aqueous solubility of water-insoluble or slightly water-soluble drugs
    Patent number: 11510859
    Abstract: A method of increasing the solubility of a water-insoluble or slightly water-soluble hydrophobic organic compound in an aqueous solvent includes adding a saponin component selected from escin, glycyrrhizin, and Quillaya saponaria extract to the aqueous solvent in an amount sufficient to trigger the formation of micelles, wherein in a first step the hydrophobic organic compound is pre-dissolved in an organic solvent, and in a second step the organic solvent comprising the pre-dissolved compound is admixed to the aqueous solvent, whereby at least a part of the insoluble or slightly soluble hydrophobic organic compound gets solubilized and dissolved in the aqueous solvent, yielding an aqueous composition having an increased concentration of said organic compound dissolved therein. Also indicated are pharmaceutical or cosmetic compositions including a water-insoluble or slightly water-soluble organic compound dissolved in an aqueous solvent at substantially increased concentrations.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: November 29, 2022
    Assignee: MARINOMED BIOTECH AG
    Inventors: Andreas Grassauer, Eva Prieschl-Grassauer, Angelika Bodenteich, Martina Morokutti-Kurz, Sabine Nakowitsch, Cornelia Kaintz
  • METHOD FOR IMPROVING AQUEOUS SOLUBILITY OF WATER-INSOLUBLE OR SLIGHTLY WATER-SOLUBLE DRUGS
    Publication number: 20190060202
    Abstract: A method of increasing the solubility of a water-insoluble or slightly water-soluble hydrophobic organic compound in an aqueous solvent includes adding a saponin component selected from escin, glycyrrhizin, and Quillaya saponaria extract to the aqueous solvent in an amount sufficient to trigger the formation of micelles, wherein in a first step the hydrophobic organic compound is pre-dissolved in an organic solvent, and in a second step the organic solvent comprising the pre-dissolved compound is admixed to the aqueous solvent, whereby at least a part of the insoluble or slightly soluble hydrophobic organic compound gets solubilized and dissolved in the aqueous solvent, yielding an aqueous composition having an increased concentration of said organic compound dissolved therein. Also indicated are pharmaceutical or cosmetic compositions including a water-insoluble or slightly water-soluble organic compound dissolved in an aqueous solvent at substantially increased concentrations.
    Type: Application
    Filed: July 15, 2016
    Publication date: February 28, 2019
    Applicant: MARINOMED BIOTECH AG
    Inventors: Andreas GRASSAUER, Eva PRIESCHL-GRASSAUER, Angelika BODENTEICH, Martina MOROKUTTI-KURZ, Sabine NAKOWITSCH, Cornelia KAINTZ