Patents by Inventor Cornelia Kruse-Mueller

Cornelia Kruse-Mueller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100136519
    Abstract: The invention concerns a process for the immunological determination of a specific antibody in a fluid sample. The process involves incubating the fluid sample in the presence of a solid phase with two antigens directed against the antibody whose presence is to be determined; the first antigen carries at least one marker group, while the second is either (a) bonded to the solid phase or (b) present in a form in which it can bond with the solid phase, and betrays the presence of the antibody being sought by showing the presence of the marker group in the solid phase and/or in the fluid phase. The proposed process is characterised by the fact that at least one of the two antigens has several epitopic regions which react with the antibody to be determined.
    Type: Application
    Filed: October 27, 2009
    Publication date: June 3, 2010
    Applicant: Roche Diagnostics GmbH
    Inventors: Ursula-Henrike Wienhues, Cornelia Kruse-Müller, Eva Höss, Elke Faatz, Beatus Ofenloch-Hähnle, Christoph Seidel, Michael Wiedmann
  • Patent number: 7629295
    Abstract: The invention concerns a method for the immunological determination of a specific antibody in a sample liquid in which the sample liquid is incubated in the presence of a solid phase with two antigens directed against the antibody to be determined of which the first antigen carries at least one marker group and the second antigen is (a) bound to the solid phase or (b) is present in a form capable of binding to the solid phase and the antibody to be determined is detected by determining the marker group in the solid phase or/and in the liquid phase characterized in that at least one of the two antigens contains several epitope regions which react with the antibody to be determined.
    Type: Grant
    Filed: July 7, 2003
    Date of Patent: December 8, 2009
    Assignee: Roche Diagnostics GmbH
    Inventors: Ursula-Henrike Wienhues, Cornelia Kruse-Müller, Eva Höss, Elke Faatz, Beatus Ofenloch-Hähnle, Christoph Seidel, Michael Wiedmann
  • Patent number: 6613530
    Abstract: The invention concerns a method for the immunological determination of a specific antibody in a sample liquid in which the sample liquid is incubated in the presence of a solid phase with two antigens directed against the antibody to be determined of which the first antigen carries at least one marker group and the second antigen is (a) bound to the solid phase or (b) is present in a form capable of binding to the solid phase and the antibody to be determined is detected by determining the marker group in the solid phase or/and in the liquid phase characterized in that at least one of the two antigens contains several epitope regions which react with the antibody to be determined.
    Type: Grant
    Filed: January 24, 1997
    Date of Patent: September 2, 2003
    Assignee: Roche Diagnostics GmbH
    Inventors: Ursula-Henrike Wienhues, Cornelia Kruse-Müller, Eva Höss, Elke Faatz, Beatus Ofenloch-Hähnle, Christoph Seidel, Michael Wiedmann
  • Patent number: 6066455
    Abstract: Method of detecting a nucleic acid by converting the nucleic acid into a single-stranded nucleic acid under alkaline conditions, wherein at least one detergent from the group of anionic, non-ionic and zwitterionic detergents is present, adding an immobilizable or immobilized capture probe, hybridizing the capture probe with the nucleic acid under immobilization of the nucleic acid via the capture probe and detecting the amount of synthesized, immobilized hybrid.
    Type: Grant
    Filed: November 17, 1997
    Date of Patent: May 23, 2000
    Assignee: Roche Diagnostics GmbH
    Inventors: Cornelia Kruse-Mueller, Stefanie Koehler
  • Patent number: 6027885
    Abstract: Method for immobilizing nucleic acids by hybridizing the nucleic acid with a capture probe. The capture probe is protected against enzymatic extension and/or enzymatic degradation of the formed hybrid.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: February 22, 2000
    Assignee: Roche Diagnostics GmbH
    Inventors: Cornelia Kruse-Mueller, Sibylle Berner, Cortina Kaletta
  • Patent number: 5639609
    Abstract: Method for immobilizing nucleic acids by hybridizing the nucleic acid with a capture probe. The capture probe is protected against enzymatic extension and/or enzymatic degradation of the formed hybrid.
    Type: Grant
    Filed: June 9, 1994
    Date of Patent: June 17, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Cornelia Kruse-Mueller, Sibylle Berner, Cortina Kaletta