Patents by Inventor Cornelis E. Hack

Cornelis E. Hack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT HUMAN ALPHA1- ANTITRYPSIN
    Publication number: 20120214747
    Abstract: The present invention relates recombinant human ?1-antitrypsin (rhAAT) comprising N-linked glycans, wherein at least 10% of said N-linked glycans are tetra-antennary glycans; and the degree of capping with sialic acid on said N-linked glycans (Z/A) is at least 50%. The invention further relates to rhAAT for use as a medicament, in particular for use in the prevention and/or treatment of a disease associated with AAT deficiency, and/or a disease involving neutrophil-mediated tissue damage.
    Type: Application
    Filed: April 20, 2010
    Publication date: August 23, 2012
    Inventors: Elisabeth C.M. Brinkman, Cornelis E. Hack, Ingrid Van Den Nieuwenhof