Patents by Inventor Cornelis Hofman

Cornelis Hofman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Purification of Progesterone Receptor Modulators
    Publication number: 20110178311
    Abstract: Processes are provided for purifying a compound of the structure (I): wherein, A, B, T, Q and R1 are defined herein, and wherein the process includes dissolving the compound of formula I in a solution containing acetone, water and a base at about 30° C.; filtering the solution containing the compound of formula I at about 30° C.; and precipitating the purified compound of formula I by adjusting the filtered solution to an acidic pH. Desirably, the compound of formula I is 5-(2-thioxospiro[cyclohexane-1,3-[3H]indol]-5-yl)-1-methylpyrrole-2-carbonitrile or tanaproget.
    Type: Application
    Filed: April 1, 2011
    Publication date: July 21, 2011
    Applicant: Wyeth LLC
    Inventors: Mahmut Levent, Panolil Raveendranath, Bogdan Wilk, Donald Carl Boop, Marinus Cornelis Hofman
  • Purification of progesterone receptor modulators
    Publication number: 20070213526
    Abstract: Processes are provided for purifying a compound of the structure: wherein, A, B, T, Q and R1 are defined herein, and wherein the process includes dissolving the compound of formula I in a solution containing acetone, water and a base at about 30° C.; filtering the solution containing the compound of formula I at about 30° C.; and precipitating the purified compound of formula I by adjusting the filtered solution to an acidic pH. Desirably, the compound of formula I is 5-(2-thioxospiro[cyclohexane-1,3-[3H]indol]-5-yl)-1-methylpyrrole-2-carbonitrile or tanaproget.
    Type: Application
    Filed: March 5, 2007
    Publication date: September 13, 2007
    Applicant: Wyeth
    Inventors: Mahmut Levent, Panolil Raveendranath, Bogdan Wilk, Donald Carl Boop, Marinus Cornelis Hofman
  • Process for obtaining oryzanol
    Publication number: 20010047101
    Abstract: Process for the obtaining of an oryzanol concentrate from an oryzanol containing fatty substance which preferably is a crude oil, by the steps of
    Type: Application
    Filed: July 3, 2001
    Publication date: November 29, 2001
    Applicant: Lipton, Division of Conopco, Inc.
    Inventors: Marnix P. van Amerongen, Cornelis Hofman, Arend Zwanenburg
  • Flavoring food compositions
    Patent number: 6117469
    Abstract: An olive oil flavor is imparted to a bland triglyceride oil by conducting an inert gas through olive oil, the flavor donating oil, and subsequently through a preferably cooler receptor triglyceride oil in which the olive oil flavor substance is absorbed. In order to prevent off-flavor formation the temperature of the donor oil is restricted to 0.degree.-65.degree. C.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: September 12, 2000
    Assignee: Lipton, division of Conopco, Inc.
    Inventors: Keshab Lal Ganguli, Cornelis Hofman, Anton Reid Van Immerseel, Karel Petrus Van Putte
  • Modification of edible oil flavor
    Patent number: 5637338
    Abstract: A useful method for shifting the flavour balance of edible oils comprises sparging nitrogen through the oil at a temperature of 20.degree.-65.degree. C. Olive oil is preferably treated at 30.degree.-40.degree. C. The treatment may be combined with usual purification steps as are washing and filtration over a filter aid.
    Type: Grant
    Filed: September 7, 1995
    Date of Patent: June 10, 1997
    Assignee: Unilever Patent Holdings BV
    Inventors: Gerardus M. Van Aalst, Cornelis Hofman, Marcho S. Kouumdjiev, Adrianus J. Kuin, Karel P. Van Putte