Patents by Inventor Cornelius Stephan HARLACHER

Cornelius Stephan HARLACHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide
    Patent number: 11434204
    Abstract: This invention relates to a process for the preparation of Form A of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form A of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide, or pharmaceutical compositions thereof, obtainable by the process described herein.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: September 6, 2022
    Assignee: MEREO BIOPHARMA 1 LIMITED
    Inventors: Osama Suleiman, Lucia Romero Perez, Cornelius Stephan Harlacher, Stewart Jones
  • METHOD FOR PRODUCING A POLYMORPHIC FORM OF 3-[5-AMINO-4-(3-CYANOBENZOYL)-PYRAZOL-1-YL]-N-CYCLOPROPYL-4-METHYLBENZAMIDE
    Publication number: 20210206726
    Abstract: This invention relates to a process for the preparation of Form A of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form A of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide, or pharmaceutical compositions thereof, obtainable by the process described herein.
    Type: Application
    Filed: January 14, 2021
    Publication date: July 8, 2021
    Applicant: MEREO BIOPHARMA 1 LIMITED
    Inventors: Osama SULEIMAN, Lucia Romero PEREZ, Cornelius Stephan HARLACHER, Stewart JONES
  • 3'-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid and its salts formulation
    Publication number: 20210169854
    Abstract: Disclosed are novel pharmaceutical formulation containing 3?-[(2Z)-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazino]-2?-hydroxy-[1,1?-biphenyl]-3-carboxylic acid or a pharmaceutically acceptable salt thereof and processes for preparing the same.
    Type: Application
    Filed: September 18, 2020
    Publication date: June 10, 2021
    Inventors: Mangesh Sadashiv Bordawekar, Stephanie Kay Dodd, Cornelius Stephan Harlacher, Jithin K John, Pravin Karmuse, Saran Kumar, Sangeetha Kumari, Vishnu Maremanda, Parthkumar Patel, Kanhaiyalal Patidar, Kapil Patil, Alan Edward Royce, Shaikh Mohsin Shaikh Hamid, Mauro Serratoni, Henricus Lambertus Gerardus Maria Tiemessen, Daya D Verma, Sunita Yadav
  • Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide
    Patent number: 10995071
    Abstract: This invention relates to a process for the preparation of Form B of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form B of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide, or pharmaceutical compositions thereof, obtainable by the process described herein.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: May 4, 2021
    Assignee: MEREO BIOPHARMA 1 LIMITED
    Inventors: Osama Suleiman, Lucia Romero Perez, Cornelius Stephan Harlacher, Stewart Jones
  • Method for producing a polymorphic form of 3-[5-amino-4-(3- cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide
    Patent number: 10934260
    Abstract: This invention relates to a process for the preparation of Form A of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form A of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide, or pharmaceutical compositions thereof, obtainable by the process described herein.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: March 2, 2021
    Assignee: MEREO BIOPHARMA 1 LIMITED
    Inventors: Osama Suleiman, Lucia Romero Perez, Cornelius Stephan Harlacher, Stewart Jones
  • METHOD FOR PRODUCING A POLYMORPHIC FORM OF 3-[5-AMINO-4-(3- CYANOBENZOYL)-PYRAZOL-1-YL]-N-CYCLOPROPYL-4-METHYLBENZAMIDE
    Publication number: 20190352269
    Abstract: This invention relates to a process for the preparation of Form A of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form A of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide, or pharmaceutical compositions thereof, obtainable by the process described herein.
    Type: Application
    Filed: July 13, 2017
    Publication date: November 21, 2019
    Applicant: MEREO BIOPHARMA 1 LIMITED
    Inventors: Osama SULEIMAN, Lucia Romero PEREZ, Cornelius Stephan HARLACHER, Stewart JONES
  • METHOD FOR PRODUCING A POLYMORPHIC FORM OF 3-[5-AMINO-4-(3-CYANOBENZOYL)-PYRAZOL-1-YL]-N-CYCLOPROPYL-4-METHYLBENZAMIDE
    Publication number: 20190315694
    Abstract: This invention relates to a process for the preparation of Form B of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide. Also disclosed herein is Form B of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide, or pharmaceutical compositions thereof, obtainable by the process described herein.
    Type: Application
    Filed: July 13, 2017
    Publication date: October 17, 2019
    Applicant: MEREO BIOPHARMA 1 LIMITED
    Inventors: Osama SULEIMAN, Lucia Romero PEREZ, Cornelius Stephan HARLACHER, Stewart JONES